| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L033521
BDB033521
|
BDBM661051
Cn1cc(-c2ccc(CNc3ccc(F)c(NC(=O)CCc4ccsc4)c3)cc2)cn1
|
C24H23FN4OS 434.540000 |
ZCJHEWGVKGGCNZ-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM661051; PubChem:CID163286455
|
Local ready
Direct docking supported
|
|
E3L033522
BDB033522
|
BDBM661052
Cn1cc(-c2ccc(CNc3ccc(F)c(NC(=O)/C=C/c4ccco4)c3)cc2)cn1
|
C24H21FN4O2 416.456000 |
LPBCGQKTMKAFNE-PKNBQFBNSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM661052; PubChem:CID163286491
|
Local ready
Direct docking supported
|
|
E3L033523
BDB033523
|
BDBM661053
Cn1cc(-c2ccc(CNc3ccc(F)c(NC(=O)C=Cc4ccccc4)c3)cc2)cn1
|
C26H23FN4O 426.495000 |
CYXAMOMUWHZSKV-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM661053; PubChem:CID171665284
|
Local ready
Direct docking supported
|
|
E3L033524
BDB033524
|
PROTAC BTK Degrader-10
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C42H49N11O4 771.927000 |
IFISVDOJTJUTBK-WUFINQPMSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662947; PubChem:CID169081326
|
Local ready
Direct docking supported
|
|
E3L033525
BDB033525
|
US12172992, Example 2
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@H]4C)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C42H49N11O4 771.927000 |
IFISVDOJTJUTBK-VSGBNLITSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662948; PubChem:CID169081263
|
Local ready
Direct docking supported
|
|
E3L033526
BDB033526
|
US12172992, Example 3
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)CC4)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C41H47N11O4 757.900000 |
XTTYHHPEDDXLEH-HHHXNRCGSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662949; PubChem:CID169081264
|
Local ready
Direct docking supported
|
|
E3L033527
BDB033527
|
US12172992, Example 4
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)c(F)c5)C[C@@H]4C)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C42H48FN11O4 789.917000 |
XZWLTIJDAOOAOZ-RRPNLBNLSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662950; PubChem:CID169081285
|
Local ready
Direct docking supported
|
|
E3L033528
BDB033528
|
US12172992, Example 5
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)c(F)c5)C[C@H]4C)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C42H48FN11O4 789.917000 |
XZWLTIJDAOOAOZ-KAYWLYCHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662951; PubChem:CID169081270
|
Local ready
Direct docking supported
|
|
E3L033529
BDB033529
|
US12172992, Example 6
CC[C@H]1CN(CCc2ccc(N3CCC(=O)NC3=O)cc2)CCN1c1ccc(Nc2cc(-c3ccc([C@@H](C)NC(=O)c4nc(C(C)(C)C)no4)c(C)c3)ncn2)nc1
|
C43H51N11O4 785.954000 |
HJKHARHYGJCYLQ-MVSFAKPFSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662952; PubChem:CID169081318
|
Local ready
Direct docking supported
|
|
E3L033530
BDB033530
|
US12172992, Example 7
CC[C@H]1CN(CCc2ccc(N3CCC(=O)NC3=O)c(F)c2)CCN1c1ccc(Nc2cc(-c3ccc([C@@H](C)NC(=O)c4nc(C(C)(C)C)no4)c(C)c3)ncn2)nc1
|
C43H50FN11O4 803.944000 |
ZXUCGFSMGYJNRI-OFSOJUDTSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662953; PubChem:CID169081340
|
Local ready
Direct docking supported
|
|
E3L033531
BDB033531
|
US12172992, Example 8
CC[C@@H]1CN(CCc2ccc(N3CCC(=O)NC3=O)cc2)CCN1c1ccc(Nc2cc(-c3ccc([C@@H](C)NC(=O)c4nc(C(C)(C)C)no4)c(C)c3)ncn2)nc1
|
C43H51N11O4 785.954000 |
HJKHARHYGJCYLQ-GRKNLSHJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662954; PubChem:CID169081311
|
Local ready
Direct docking supported
|
|
E3L033532
BDB033532
|
US12172992, Example 9
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)CC4(C)C)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C43H51N11O4 785.954000 |
FFERLSHFMZMHLG-MUUNZHRXSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662955; PubChem:CID169081338
|
Local ready
Direct docking supported
|
|
E3L033533
BDB033533
|
US12172992, Example 10
Cc1c([C@@H](C)NC(=O)c2nc(C(C)(C)C)no2)ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)c1F
|
C42H48FN11O4 789.917000 |
HKJLLZRGVOIGSI-AHKZPQOWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662956; PubChem:CID169081341
|
Local ready
Direct docking supported
|
|
E3L033534
BDB033534
|
US12172992, Example 11
Cc1c([C@@H](C)NC(=O)c2nc(C(C)(C)C)no2)ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)CC4)cn3)ncn2)c1F
|
C41H46FN11O4 775.890000 |
DXAMCKURBGAPRL-AREMUKBSSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662957; PubChem:CID169081291
|
Local ready
Direct docking supported
|
|
E3L033535
BDB033535
|
US12172992, Example 12
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)CC4)cn3)ncn2)c(F)cc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C41H46FN11O4 775.890000 |
VCYKHFWTVADJIM-AREMUKBSSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662958; PubChem:CID169081330
|
Local ready
Direct docking supported
|
|
E3L033536
BDB033536
|
US12172992, Example 13
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C(C)C)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C44H53N11O4 799.981000 |
FJLQPZAPFKXILN-JQMWFGOGSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662959; PubChem:CID169081271
|
Local ready
Direct docking supported
|
|
E3L033537
BDB033537
|
US12172992, Example 14
C[C@@H](NC(=O)c1nc(C(C)(C)C)no1)c1ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)cc1Cl
|
C41H46ClN11O4 792.345000 |
DQWWVCQXTSHOSR-IZZNHLLZSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662960; PubChem:CID169081333
|
Local ready
Direct docking supported
|
|
E3L033538
BDB033538
|
US12172992, Example 15
COC[C@H]1CN(CCc2ccc(N3CCC(=O)NC3=O)cc2)CCN1c1ccc(Nc2cc(-c3ccc([C@@H](C)NC(=O)c4nc(C(C)(C)C)no4)c(C)c3)ncn2)nc1
|
C43H51N11O5 801.953000 |
HWIOHEPNEVRULC-LHXZUMEBSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662961; PubChem:CID169081308
|
Local ready
Direct docking supported
|
|
E3L033539
BDB033539
|
US12172992, Example 16
C[C@@H](NC(=O)c1nc(C(C)(C)C)no1)c1ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)cc1C(F)(F)F
|
C42H46F3N11O4 825.897000 |
FBCKBVQQCMIWBW-IZZNHLLZSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662962; PubChem:CID169081282
|
Local ready
Direct docking supported
|
|
E3L033540
BDB033540
|
US12172992, Example 17
C[C@@H](NC(=O)c1nc(C(C)(C)C)no1)c1ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)cc1F
|
C41H46FN11O4 775.890000 |
WCKXKIOIVQPJQO-IZZNHLLZSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662963; PubChem:CID169081268
|
Local ready
Direct docking supported
|