| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035421
BDB035421
|
BDBM710712
CCNc1cc(C2(c3nncn3C)CC(F)(F)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C29H32F5N7O 589.613000 |
LFWOSFIIDBDMCH-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710712
|
Local ready
Direct docking supported
|
|
E3L035422
BDB035422
|
BDBM710713
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@]3(c4nncn4C)C[C@H](C#N)C3)c1)C2=O
|
C32H36F3N7O 591.682000 |
AIKXFQYBAQZYOI-HVHLLGLASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710713
|
Local ready
Direct docking supported
|
|
E3L035423
BDB035423
|
BDBM710714
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@]3(c4nncn4C)C[C@@H](C#N)C3)c1)C2=O
|
C32H36F3N7O 591.682000 |
AIKXFQYBAQZYOI-KLYZNTHZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710714
|
Local ready
Direct docking supported
|
|
E3L035424
BDB035424
|
BDBM710715
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC2(COC2)C1
|
C30H32F3N5O2 551.613000 |
HCJLZDRUCWBKBD-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710715; PubChem:CID168262477
|
Local ready
Direct docking supported
|
|
E3L035425
BDB035425
|
BDBM710716
C[C@H]1CCCN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc(C4(c5nncn5C)CC5(COC5)C4)c2)C3=O)C1
|
C31H34F3N5O2 565.640000 |
KOOHGEPKDRNWTM-FQEVSTJZSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710716; PubChem:CID168263075
|
Local ready
Direct docking supported
|
|
E3L035426
BDB035426
|
BDBM710717
Cn1cnnc1[C@]1(c2cc(NC3CCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](C)C1
|
C32H38F3N7O 593.698000 |
HUWWFMIOBNQUBG-NJTBPKAJSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710717
|
Local ready
Direct docking supported
|
|
E3L035427
BDB035427
|
BDBM710718
Cn1cnnc1[C@]1(c2cc(NC3CCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](C)C1
|
C32H38F3N7O 593.698000 |
HUWWFMIOBNQUBG-HQLWIIKZSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710718
|
Local ready
Direct docking supported
|
|
E3L035428
BDB035428
|
BDBM710719
CO[C@H]1C[C@@](c2cc(NC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H40F3N7O2 623.724000 |
AIEPQAYTYHKSAX-HBPSFDQZSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710719
|
Local ready
Direct docking supported
|
|
E3L035429
BDB035429
|
BDBM710720
CO[C@H]1C[C@](c2cc(NC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H40F3N7O2 623.724000 |
AIEPQAYTYHKSAX-FVQXVRMNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710720
|
Local ready
Direct docking supported
|
|
E3L035430
BDB035430
|
BDBM710721
CC1=C[C@@](c2cc(NC3CCC3)nc(N3Cc4c(cc(CN5CCN(C)C[C@@H]5C(C)C)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C35H43F3N8O 648.778000 |
ILGMYQYCPUUOPG-ANHUGMMASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710721
|
Local ready
Direct docking supported
|
|
E3L035431
BDB035431
|
BDBM710722
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)(F)F)c1)CN(c1cc([C@]3(c4nncn4C)C[C@@H](C)C3)cc(OC3CCCC3)n1)C2=O
|
C36H46F3N7O2 665.805000 |
DHNJHSZXQFFMAJ-SBOKMITGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710722
|
Local ready
Direct docking supported
|
|
E3L035432
BDB035432
|
BDBM710723
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)(F)F)c1)CN(c1cc([C@]3(c4nncn4C)C[C@H](C)C3)cc(OC3CCCC3)n1)C2=O
|
C36H46F3N7O2 665.805000 |
DHNJHSZXQFFMAJ-SJMANEQPSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710723
|
Local ready
Direct docking supported
|
|
E3L035433
BDB035433
|
BDBM710724
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)(F)F)c1)CN(c1cc([C@]3(c4nncn4C)C[C@@H](C)C3)cc(NC3CCCC3)n1)C2=O
|
C36H47F3N8O 664.821000 |
PJLNANCIFHCOOI-SBOKMITGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710724
|
Local ready
Direct docking supported
|
|
E3L035434
BDB035434
|
BDBM710725
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)(F)F)c1)CN(c1cc([C@]3(c4nncn4C)C[C@H](C)C3)cc(NC3CCCC3)n1)C2=O
|
C36H47F3N8O 664.821000 |
PJLNANCIFHCOOI-SJMANEQPSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710725
|
Local ready
Direct docking supported
|
|
E3L035435
BDB035435
|
BDBM710726
CCOc1cc([C@]2(c3nncn3C)C[C@@H](OC)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C30H35F3N6O3 584.643000 |
JPWGQCPSIKGASG-VTNQZFKNSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710726
|
Local ready
Direct docking supported
|
|
E3L035436
BDB035436
|
BDBM710727
CCOc1cc([C@]2(c3nncn3C)C[C@H](OC)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C30H35F3N6O3 584.643000 |
JPWGQCPSIKGASG-BXJXBJKFSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710727
|
Local ready
Direct docking supported
|
|
E3L035437
BDB035437
|
BDBM710728
CO[C@H]1C[C@@](c2cc(OC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H39F3N6O3 624.708000 |
JAJJGVWYJBWVIX-HBPSFDQZSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710728
|
Local ready
Direct docking supported
|
|
E3L035438
BDB035438
|
BDBM710729
CO[C@H]1C[C@](c2cc(OC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H39F3N6O3 624.708000 |
JAJJGVWYJBWVIX-FVQXVRMNSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710729
|
Local ready
Direct docking supported
|
|
E3L035439
BDB035439
|
BDBM710730
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](CC#N)C1
|
C30H31F3N6O 548.613000 |
OQCCIANNQMEJOB-CGSFZAOMSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710730
|
Local ready
Direct docking supported
|
|
E3L035440
BDB035440
|
BDBM710731
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](CC#N)C1
|
C30H31F3N6O 548.613000 |
OQCCIANNQMEJOB-PHYNJUQWSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710731
|
Local ready
Direct docking supported
|