| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035361
BDB035361
|
BDBM710544
Cn1cnnc1[C@](O)(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CCC1
|
C29H32F3N5O2 539.602000 |
WTAQCNIHHUWNEI-MUUNZHRXSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710544; PubChem:CID168262817
|
Local ready
Direct docking supported
|
|
E3L035362
BDB035362
|
BDBM710620
Cn1cnnc1[C@@](O)(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CCC1
|
C29H32F3N5O2 539.602000 |
WTAQCNIHHUWNEI-NDEPHWFRSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710620; PubChem:CID168262939
|
Local ready
Direct docking supported
|
|
E3L035363
BDB035363
|
BDBM710654
CCOc1cc([C@]2(c3nncn3C)C[C@H](C)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C30H35F3N6O2 568.644000 |
UKFKDADMCDDXJG-QZBFGZBCSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710654
|
Local ready
Direct docking supported
|
|
E3L035364
BDB035364
|
BDBM710655
CCNc1cc([C@]2(c3nncn3C)C[C@@H](C)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C30H36F3N7O 567.660000 |
WMPCQFUYGVNZQX-HGBJFFEJSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710655
|
Local ready
Direct docking supported
|
|
E3L035365
BDB035365
|
BDBM710656
CCNc1cc([C@]2(c3nncn3C)C[C@H](C)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C30H36F3N7O 567.660000 |
WMPCQFUYGVNZQX-QZBFGZBCSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710656
|
Local ready
Direct docking supported
|
|
E3L035366
BDB035366
|
BDBM710657
CCNc1cc(C2(c3nncn3C)CC3(COC3)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C31H36F3N7O2 595.670000 |
IQTVWALDAQLAGA-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710657
|
Local ready
Direct docking supported
|
|
E3L035367
BDB035367
|
BDBM710658
CO[C@H]1C[C@@](c2cc(NC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H40F3N7O2 623.724000 |
AIEPQAYTYHKSAX-HBPSFDQZSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710658
|
Local ready
Direct docking supported
|
|
E3L035368
BDB035368
|
BDBM710659
CO[C@H]1C[C@](c2cc(NC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H40F3N7O2 623.724000 |
AIEPQAYTYHKSAX-FVQXVRMNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710659
|
Local ready
Direct docking supported
|
|
E3L035369
BDB035369
|
BDBM710660
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)F)c1)CN(c1cccc([C@H](c3nncn3C)C3COC3)c1)C2=O
|
C31H38F2N6O2 564.681000 |
JRZCPGJUGHWRQT-IZLXSDGUSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710660; PubChem:CID175664871
|
Local ready
Direct docking supported
|
|
E3L035370
BDB035370
|
BDBM710661
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O
|
C31H38F2N6O2 564.681000 |
JRZCPGJUGHWRQT-VSGBNLITSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710661; PubChem:CID175664872
|
Local ready
Direct docking supported
|
|
E3L035371
BDB035371
|
BDBM710662
COC1CC([C@H](c2cccc(N3Cc4c(cc(CN5CCN(C)C[C@@H]5C(C)C)cc4C(F)F)C3=O)c2)c2nncn2C)C1
|
C33H42F2N6O2 592.735000 |
YJMWLWKXYJRSBL-SLNMLDGESA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710662
|
Local ready
Direct docking supported
|
|
E3L035372
BDB035372
|
BDBM710663
COC1CC([C@H](c2cccc(N3Cc4c(cc(CN5CCN(C)C[C@@H]5C(C)C)cc4C(F)F)C3=O)c2)c2nncn2C)C1
|
C33H42F2N6O2 592.735000 |
YJMWLWKXYJRSBL-SLNMLDGESA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710663
|
Local ready
Direct docking supported
|
|
E3L035373
BDB035373
|
BDBM710664
COC1CC([C@@H](c2cccc(N3Cc4c(cc(CN5CCN(C)C[C@@H]5C(C)C)cc4C(F)F)C3=O)c2)c2nncn2C)C1
|
C33H42F2N6O2 592.735000 |
YJMWLWKXYJRSBL-KTXLJNIASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710664
|
Local ready
Direct docking supported
|
|
E3L035374
BDB035374
|
BDBM710665
COC1CC([C@@H](c2cccc(N3Cc4c(cc(CN5CCN(C)C[C@@H]5C(C)C)cc4C(F)F)C3=O)c2)c2nncn2C)C1
|
C33H42F2N6O2 592.735000 |
YJMWLWKXYJRSBL-KTXLJNIASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710665
|
Local ready
Direct docking supported
|
|
E3L035375
BDB035375
|
BDBM710666
Cn1cnnc1C1(c2cc(C3CC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC(F)(F)C1
|
C30H31F5N6O 586.609000 |
BKFMJUUGFQKVEV-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710666
|
Local ready
Direct docking supported
|
|
E3L035376
BDB035376
|
BDBM710667
CCNc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc(C2(c3nncn3C)CC(F)(F)C2)c1
|
C30H33F5N6O 588.625000 |
CUMCRGNQXBJWCW-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710667; PubChem:CID170038927
|
Local ready
Direct docking supported
|
|
E3L035377
BDB035377
|
BDBM710668
C=C1CC(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H30F3N5O 521.587000 |
NPQXBWUMESYMDC-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710668; PubChem:CID168262916
|
Local ready
Direct docking supported
|
|
E3L035378
BDB035378
|
BDBM710669
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC(=O)C1
|
C28H28F3N5O2 523.559000 |
IKJUHEILBKWLHF-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710669; PubChem:CID168835367
|
Local ready
Direct docking supported
|
|
E3L035379
BDB035379
|
BDBM710670
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](O)C1
|
C28H30F3N5O2 525.575000 |
HXENBONILQLPNV-DXKIZBQOSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710670
|
Local ready
Direct docking supported
|
|
E3L035380
BDB035380
|
BDBM710671
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](O)C1
|
C28H30F3N5O2 525.575000 |
HXENBONILQLPNV-GHKKRPSHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710671
|
Local ready
Direct docking supported
|