| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L036261
BDB036261
|
US12252493, Example 30
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(CNC4CCC4)nc23)n(C)n1
|
C25H28FN7O 461.545000 |
SJNXIPYOADQGQY-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727080; PubChem:CID155369126
|
Local ready
Direct docking supported
|
|
E3L036262
BDB036262
|
US12252493, Example 31
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(CN4CC(O)C4)nc23)n(C)n1
|
C24H26FN7O2 463.517000 |
GZEWCBIOBFIUKR-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727081; PubChem:CID155383022
|
Local ready
Direct docking supported
|
|
E3L036263
BDB036263
|
US12252493, Example 32
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(CNCc4ccccc4)nc23)n(C)n1
|
C28H28FN7O 497.578000 |
WUYPNCHTJRNDKQ-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727082; PubChem:CID155383025
|
Local ready
Direct docking supported
|
|
E3L036264
BDB036264
|
US12252493, Example 33
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(CNC4CC4)nc23)n(C)n1
|
C24H26FN7O 447.518000 |
SPKYLNOMUKTJPO-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727083; PubChem:CID155383019
|
Local ready
Direct docking supported
|
|
E3L036265
BDB036265
|
US12252493, Example 34
Cc1cc(S(C)(=O)=O)ccc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cc(C(C)N)nc12
|
C25H26FN5O3S 495.580000 |
MYZIPYGLTAKQIH-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727084; PubChem:CID155369236
|
Local ready
Direct docking supported
|
|
E3L036266
BDB036266
|
US12252493, Example 35
Cc1cc(C(=O)N(C)C)ncc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cc(C(C)N)nc12
|
C26H28FN7O2 489.555000 |
RCFQCFYOMONSLA-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727085; PubChem:CID155383017
|
Local ready
Direct docking supported
|
|
E3L036267
BDB036267
|
US12252493, Example 36
CC(N)c1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cc(C(F)(F)F)nn3C)c2n1
|
C22H21F4N7O 475.450000 |
BNMLZLDNWDTKQZ-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727086; PubChem:CID155383023
|
Local ready
Direct docking supported
|
|
E3L036268
BDB036268
|
US12252493, Example 37
Cc1cc(CN(C)C)ccc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cc(C(C)N)nc12
|
C27H31FN6O 474.584000 |
TZDSJUOCXJAUEP-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727087; PubChem:CID155383018
|
Local ready
Direct docking supported
|
|
E3L036269
BDB036269
|
US12252493, Example 38
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C(C)N)nc23)ccn1
|
C23H23FN6O 418.476000 |
ATTDJLYHFKMFME-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727088; PubChem:CID155383020
|
Local ready
Direct docking supported
|
|
E3L036270
BDB036270
|
US12252493, Example 39
Cc1ncccc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cc(C(C)N)nc12
|
C23H23FN6O 418.476000 |
LOBZJLAGRIYYGQ-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727089; PubChem:CID155383021
|
Local ready
Direct docking supported
|
|
E3L036271
BDB036271
|
US12252493, Example 40
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C(C)N)nc23)n(C)n1
|
C22H24FN7O 421.480000 |
CJLVIMOZCUQEAJ-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727090; PubChem:CID155369214
|
Local ready
Direct docking supported
|
|
E3L036272
BDB036272
|
US12252493, Example 41
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C(N)C4CC4)nc23)n(C)n1
|
C24H26FN7O 447.518000 |
KEXZENJSPDNQRT-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727091; PubChem:CID155369143
|
Local ready
Direct docking supported
|
|
E3L036273
BDB036273
|
US12252493, Example 42
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C(N)C(F)(F)F)nc23)n(C)n1
|
C22H21F4N7O 475.450000 |
SHHKMZXKPTUBAY-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727092; PubChem:CID155369144
|
Local ready
Direct docking supported
|
|
E3L036274
BDB036274
|
US12252493, Example 43
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(-c4nn[nH]n4)nc23)n(C)n1
|
C21H19FN10O 446.450000 |
ARVNNNAHZHBLFN-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727093; PubChem:CID155369140
|
Local ready
Direct docking supported
|
|
E3L036275
BDB036275
|
US12252493, Example 44
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(-c4nnco4)nc23)n(C)n1
|
C22H19FN8O2 446.446000 |
QSCBENZELMFGOL-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727094; PubChem:CID155369181
|
Local ready
Direct docking supported
|
|
E3L036276
BDB036276
|
US12252493, Example 45
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(-c4cnco4)nc23)n(C)n1
|
C23H20FN7O2 445.458000 |
FIABGGUWUBQLIX-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM727096; PubChem:CID155369182
|
Local ready
Direct docking supported
|
|
E3L036277
BDB036277
|
US20250092064, Example 1
CC[C@@H]1CN(Cc2cc(C(CC(=O)O)c3ccc4c(nnn4C)c3C)cc3ccsc23)S(=O)(=O)c2cc(Cl)cnc2O1
|
C29H28ClN5O5S2 626.160000 |
CHDDDULEXVACBX-FKHAVUOCSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM728814; PubChem:CID169261748
|
Local ready
Direct docking supported
|
|
E3L036278
BDB036278
|
US20250092064, Example 2
CC[C@@H]1CN(Cc2cc(C(CC(=O)O)c3ccc4c(nnn4C)c3Cl)cc3ccsc23)S(=O)(=O)c2cc(Cl)cnc2O1
|
C28H25Cl2N5O5S2 646.578000 |
JZNKDWBIKWUTGG-YMBRHYMPSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM728815; PubChem:CID169261678
|
Local ready
Direct docking supported
|
|
E3L036279
BDB036279
|
US20250092064, Example 3
CC[C@@H]1CN(Cc2cc(C(CC(=O)O)c3ccc4c(nnn4C)c3C)cc3c2CCC3)S(=O)(=O)c2cc(Cl)cnc2O1
|
C30H32ClN5O5S 610.136000 |
INIYIURZEWNDPE-UFUCKMQHSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM728816; PubChem:CID169261846
|
Local ready
Direct docking supported
|
|
E3L036280
BDB036280
|
US20250092064, Example 4
CC[C@@H]1CN(Cc2cc([C@H](CC(=O)O)c3ccc4c(nnn4C)c3C)cc3c2CCC3)S(=O)(=O)c2cc(Cl)cnc2O1
|
C30H32ClN5O5S 610.136000 |
INIYIURZEWNDPE-RDGATRHJSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM728817; PubChem:CID169261759
|
Local ready
Direct docking supported
|