| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L038761
BDB038761
|
BDBM747769
Cn1cnnc1-c1cc(C#N)ccc1-c1cc(C2CC2)nc(N2Cc3c(cc(CNCC4(O)CCC4)c(F)c3F)C2=O)c1
|
C32H29F2N7O2 581.627000 |
LUOICDDCILGBKD-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM747769; PubChem:CID167421165
|
Local ready
Direct docking supported
|
|
E3L038762
BDB038762
|
US20250186425, Example 1
CS(=O)(=O)c1ccc(C#N)cc1-c1cc(=O)c2c(Oc3ccc(Cl)cc3)cc(F)cc2[nH]1
|
C23H14ClFN2O4S 468.893000 |
UCXQPWJEIRUHMA-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM748283; PubChem:CID169182922
|
Local ready
Direct docking supported
|
|
E3L038763
BDB038763
|
US20250186425, Example 2
N#Cc1ccc(Cl)c(-c2cc(=O)c3c(Oc4ccc(Cl)cc4)cc(F)cc3[nH]2)c1
|
C22H11Cl2FN2O2 425.246000 |
COHHHXMDPRYJHR-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM748284; PubChem:CID169182917
|
Local ready
Direct docking supported
|
|
E3L038764
BDB038764
|
US20250186425, Example 3
Cn1cc(Oc2cc(F)cc3[nH]c(-c4cc(C#N)ccc4S(C)(=O)=O)cc(=O)c23)cn1
|
C21H15FN4O4S 438.440000 |
QRSGCVCSDCNFJD-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM748285; PubChem:CID169182920
|
Local ready
Direct docking supported
|
|
E3L038765
BDB038765
|
US20250186425, Example 4
Cn1cc(Oc2cc(Cl)cc3[nH]c(-c4cc(C#N)ccc4S(C)(=O)=O)cc(=O)c23)cn1
|
C21H15ClN4O4S 454.895000 |
FOPFFFSSLAQOLF-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM748286; PubChem:CID169182927
|
Local ready
Direct docking supported
|
|
E3L038766
BDB038766
|
US20250186425, Example 2
N#Cc1ccc(Cl)c(-c2cc(=O)c3c(Oc4ccc(Cl)cc4)cc(F)cc3[nH]2)c1
|
C22H11Cl2FN2O2 425.246000 |
COHHHXMDPRYJHR-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM748287; PubChem:CID169182917
|
Local ready
Direct docking supported
|
|
E3L038767
BDB038767
|
US20250186425, Example 6
N#Cc1ccc(Cl)c(-c2cc(=O)c3c(OCc4ccc(Cl)cc4)cc(F)cc3[nH]2)c1
|
C23H13Cl2FN2O2 439.273000 |
RMSPJLUETZFQRL-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM748288; PubChem:CID169182914
|
Local ready
Direct docking supported
|
|
E3L038768
BDB038768
|
US20250186425, Example 7
CS(=O)(=O)c1ccc(C#N)cc1-c1cc(=O)c2c(Cc3ccc(Cl)cc3)cc(F)cc2[nH]1
|
C24H16ClFN2O3S 466.921000 |
OAQXIJJAMUQBLZ-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM748289; PubChem:CID169182915
|
Local ready
Direct docking supported
|
|
E3L038769
BDB038769
|
H-Arg-Tyr(3-NO2)-Phe-NH2
N=C(N)NCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C24H32N8O6 528.570000 |
AGLKZPCEXKJXDE-BZSNNMDCSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748293; PubChem:CID176780166
|
Local ready
Direct docking supported
|
|
E3L038770
BDB038770
|
H-Phe(4-guanidino)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccc(N=C(N)N)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C25H35N7O3 481.601000 |
HIWLTVZFXFKVJT-ZEWNOJEFSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748295; PubChem:CID176780169
|
Local ready
Direct docking supported
|
|
E3L038771
BDB038771
|
H-Hse(guanidino)(guanidino)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCONC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C20H33N7O4 435.529000 |
MNEIZXBKPOUWNF-TUUVXOQKSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748296; PubChem:CID170209468
|
Local ready
Direct docking supported
|
|
E3L038772
BDB038772
|
H-Arg(CH2CF3)(CH2CF3)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCNC(=N)NCC(F)(F)F)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C23H36F3N7O3 515.581000 |
UUKKHWCHKBIPJL-DKIMLUQUSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748297; PubChem:CID176780168
|
Local ready
Direct docking supported
|
|
E3L038773
BDB038773
|
H-Phe(4-ureido)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccc(NC(N)=O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C25H34N6O4 482.585000 |
DOJQUDMNFNOJOJ-ZEWNOJEFSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748317; PubChem:CID170209509
|
Local ready
Direct docking supported
|
|
E3L038774
BDB038774
|
BDBM748318
CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCN(C)C(=N)NC)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C23H39N7O3 461.611000 |
UDLUCXXDMNZXIR-WNHJNPCNSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748318; PubChem:CID169180630
|
Local ready
Direct docking supported
|
|
E3L038775
BDB038775
|
BDBM748319
CNC(=N)N(C)CCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c(C)c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C27H39N7O4 525.654000 |
JQFXHNCNTRJSLJ-FKBYEOEOSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB
BindingDB:BDBM748319
|
Local ready
Direct docking supported
|
|
E3L038776
BDB038776
|
H-Ala(tetrazol-5-yl)(tetrazol-5-yl)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1nn[nH]n1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C19H28N8O3 416.486000 |
JZTNCYDQLJQSTF-PCBIJLKTSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748320; PubChem:CID176780157
|
Local ready
Direct docking supported
|
|
E3L038777
BDB038777
|
BDBM748321
CCNC(=N)N(CC)CCC[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(N)=O)[C@@H](C)CC
|
C25H43N7O3 489.665000 |
RVZUFLPPLHZCLF-VMXMFDLUSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748321; PubChem:CID176780160
|
Local ready
Direct docking supported
|
|
E3L038778
BDB038778
|
H-His(3-Me)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1cncn1C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C22H32N6O3 428.537000 |
JHXXWGIIIOPKRM-QZHFEQFPSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748322; PubChem:CID176780158
|
Local ready
Direct docking supported
|
|
E3L038779
BDB038779
|
BDBM748323
CNC(=N)N(C)CCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C26H36N8O6 556.624000 |
HQNHXIGICJGILA-UFYCRDLUSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB
BindingDB:BDBM748323
|
Local ready
Direct docking supported
|
|
E3L038780
BDB038780
|
BDBM748324
CNC(=N)N(C)CCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C26H36N8O6 556.624000 |
HQNHXIGICJGILA-UFYCRDLUSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB
BindingDB:BDBM748324
|
Local ready
Direct docking supported
|