| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L038781
BDB038781
|
H-His(1-Me)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1cn(C)cn1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C22H32N6O3 428.537000 |
RJURKSQFEQCNPE-QZHFEQFPSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748325; PubChem:CID176780154
|
Local ready
Direct docking supported
|
|
E3L038782
BDB038782
|
H-Arg(CH2CF3)(CH2CF3)-Tyr(Me)-Phe-NH2
COc1ccc(C[C@H](NC(=O)[C@@H](N)CCCNC(=N)NCC(F)(F)F)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
|
C27H36F3N7O4 579.624000 |
GQFGBSPTKCYADU-FKBYEOEOSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748326; PubChem:CID177372822
|
Local ready
Direct docking supported
|
|
E3L038783
BDB038783
|
H-Arg(Me2)-Tyr(Me)-Phe-NH2
COc1ccc(C[C@H](NC(=O)[C@@H](N)CCCNC(=N)N(C)C)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
|
C27H39N7O4 525.654000 |
DGTKNZNFSHQPEA-VABKMULXSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748327; PubChem:CID176780164
|
Local ready
Direct docking supported
|
|
E3L038784
BDB038784
|
H-D-Phe(4-guanidino)-Tyr(Me)-Phe-NH2
COc1ccc(C[C@H](NC(=O)[C@H](N)Cc2ccc(N=C(N)N)cc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
|
C29H35N7O4 545.644000 |
UVJIJLXAJPTNJM-DSITVLBTSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748328; PubChem:CID170209549
|
Local ready
Direct docking supported
|
|
E3L038785
BDB038785
|
BDBM748329
NCC(=O)N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(N)=O
|
C11H14N4O5 282.256000 |
HGFDARWBRKQDNA-ZETCQYMHSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748329; PubChem:CID169180640
|
Local ready
Direct docking supported
|
|
E3L038786
BDB038786
|
BDBM748330
NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)c([N+](=O)[O-])c1
|
C18H20N4O5 372.381000 |
MYTKKJLHGLDUJF-KBPBESRZSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748330; PubChem:CID176780162
|
Local ready
Direct docking supported
|
|
E3L038787
BDB038787
|
H-Arg(Me2)-Tyr(3-NO2)-Phe-NH2
CN(C)C(=N)NCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C26H36N8O6 556.624000 |
MVEMAQUSIJXAJW-UFYCRDLUSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748331; PubChem:CID176780163
|
Local ready
Direct docking supported
|
|
E3L038788
BDB038788
|
H-Arg(CH2CF3)(CH2CF3)-Tyr(3-Cl)-Phe-NH2
N=C(NCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c(Cl)c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)NCC(F)(F)F
|
C26H33ClF3N7O4 600.042000 |
YBKNZVIKCGFHAF-UFYCRDLUSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748332; PubChem:CID177372823
|
Local ready
Direct docking supported
|
|
E3L038789
BDB038789
|
H-2Thi-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1cccs1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C22H30N4O3S 430.574000 |
BTCMYKMDRSRZKC-QZHFEQFPSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748333; PubChem:CID176780161
|
Local ready
Direct docking supported
|
|
E3L038790
BDB038790
|
H-4Pal-Phe-Ile-NH2
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccncc1)C(N)=O
|
C23H31N5O3 425.533000 |
NCJYTFPVACXDBL-KNTRFNDTSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748334; PubChem:CID169180620
|
Local ready
Direct docking supported
|
|
E3L038791
BDB038791
|
H-4Pal-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccncc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C23H31N5O3 425.533000 |
NYJIJBKRGQVWHM-KNTRFNDTSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748335; PubChem:CID169180628
|
Local ready
Direct docking supported
|
|
E3L038792
BDB038792
|
H-Phe(4-NHAc)-xiIle-Phe-NH2
CCC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(NC(C)=O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C26H35N5O4 481.597000 |
URJLASSSOHAFDV-QVTSAZHYSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748336; PubChem:CID169180651
|
Local ready
Direct docking supported
|
|
E3L038793
BDB038793
|
H-Arg-Tyr(3-Cl)-Phe-NH2
N=C(N)NCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c(Cl)c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C24H32ClN7O4 518.018000 |
AOPLLVOEHUILGC-FHWLQOOXSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748337; PubChem:CID176780165
|
Local ready
Direct docking supported
|
|
E3L038794
BDB038794
|
BDBM748338
CC(C[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(F)(F)F
|
C21H32F3N7O3 487.527000 |
SEDUFYWKLCXXLQ-QJIWQAPWSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748338; PubChem:CID176780156
|
Local ready
Direct docking supported
|
|
E3L038795
BDB038795
|
H-Arg-DL-xiIle-Phe-NH2
CCC(C)C(NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C21H35N7O3 433.557000 |
XVVYOVGROLTMFF-DBGUYSSFSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748339; PubChem:CID169180625
|
Local ready
Direct docking supported
|
|
E3L038796
BDB038796
|
H-Arg(Me2)-Tyr(3-F)-Phe-NH2
CN(C)C(=N)NCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)c(F)c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C26H36FN7O4 529.617000 |
YWJKSRXESQEALE-ACRUOGEOSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748340; PubChem:CID169180653
|
Local ready
Direct docking supported
|
|
E3L038797
BDB038797
|
H-Arg(Me2)-Tza-Phe-NH2
CN(C)C(=N)NCCC[C@H](N)C(=O)N[C@@H](Cc1cscn1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C23H34N8O3S 502.645000 |
DHIVVRYVYJSKPY-FHWLQOOXSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748341; PubChem:CID169180634
|
Local ready
Direct docking supported
|
|
E3L038798
BDB038798
|
H-Arg(Me2)-2Thi-Phe-NH2
CN(C)C(=N)NCCC[C@H](N)C(=O)N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C24H35N7O3S 501.657000 |
JVBJWHNWEYDUKR-UFYCRDLUSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UBR1 |
BindingDB, PubChem
BindingDB:BDBM748342; PubChem:CID169180595
|
Local ready
Direct docking supported
|
|
E3L038799
BDB038799
|
H-Arg(Me2)-Pro-Phe-NH2
CN(C)C(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C22H35N7O3 445.568000 |
RLVGSUYFFHCIEO-BZSNNMDCSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748343; PubChem:CID169180644
|
Local ready
Direct docking supported
|
|
E3L038800
BDB038800
|
H-Arg(Me2)-Ile-Phe-NH2
CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCC/N=C(\N)N(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C23H39N7O3 461.611000 |
XEHSGEKOVYDRRP-WNHJNPCNSA-N | Q8IWV7, Q8IWV8 | E3 ubiquitin-protein ligase UBR1, E3 ubiquitin-protein ligase UBR2 |
BindingDB, PubChem
BindingDB:BDBM748344; PubChem:CID169180652
|
Local ready
Direct docking supported
|