| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L004481
BDB004481
|
US8618158, Ncl-00016654
O=C1c2c(Cl)cccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C21H14Cl2N2O4 429.259000 |
JYKJGOLGHPFEGJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111557; PubChem:CID58433779
|
Local ready
Direct docking supported
|
|
E3L004482
BDB004482
|
BDBM111558
CC(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C23H18ClNO3 391.854000 |
WPVMCSFCDNXBJK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111558; PubChem:CID51350115
|
Local ready
Direct docking supported
|
|
E3L004483
BDB004483
|
BDBM111559
O=C1c2ccccc2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc(I)cc1
|
C26H23ClINO3 559.831000 |
UUMATCHVJQJMCG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111559; PubChem:CID51350786
|
Local ready
Direct docking supported
|
|
E3L004484
BDB004484
|
BDBM111560
CC(=O)c1ccc(CN2C(=O)c3ccccc3C2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
|
C28H26ClNO4 475.972000 |
WULBLTKPZRXNEO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111560; PubChem:CID51351127
|
Local ready
Direct docking supported
|
|
E3L004485
BDB004485
|
BDBM111561
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1cccc2ccccc12
|
C25H18ClNO2 399.877000 |
CKAWKYGABRWDPY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111561; PubChem:CID51349839
|
Local ready
Direct docking supported
|
|
E3L004486
BDB004486
|
BDBM111563
O=C1c2ccccc2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1cccc2ccccc12
|
C30H26ClNO3 483.995000 |
HSOYSLMQKONCSZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111563; PubChem:CID51350895
|
Local ready
Direct docking supported
|
|
E3L004487
BDB004487
|
BDBM111564
O=C1c2ccccc2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1cccc(Br)c1
|
C26H23BrClNO3 512.831000 |
ZYUYGLQGFUBJPC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111564; PubChem:CID51350896
|
Local ready
Direct docking supported
|
|
E3L004488
BDB004488
|
BDBM111565
O=C1c2ccccc2C(O)(c2ccccc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C21H16N2O4 360.369000 |
JHLRZXRFMVWOLS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111565; PubChem:CID51349702
|
Local ready
Direct docking supported
|
|
E3L004489
BDB004489
|
US8618158, Ncl-00016656
O=C1c2ccccc2C(OCC2(CO)CC2)(c2ccccc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C26H24N2O5 444.487000 |
AYKWZUFNBYBYBG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111566; PubChem:CID58433791
|
Local ready
Direct docking supported
|
|
E3L004490
BDB004490
|
BDBM111567
O=C1c2ccccc2C(O)(c2ccc(F)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C21H15FN2O4 378.359000 |
JDQPEVSGVBTFKP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111567; PubChem:CID51349703
|
Local ready
Direct docking supported
|
|
E3L004491
BDB004491
|
US8618158, Ncl-00016149
O=C(O)CCC(=O)OCC1(COC2(c3ccc(Cl)cc3)c3c(Cl)cccc3C(=O)N2Cc2ccc([N+](=O)[O-])cc2)CC1
|
C30H26Cl2N2O8 613.450000 |
WGNURTQBXWVHDF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111568; PubChem:CID44551756
|
Local ready
Direct docking supported
|
|
E3L004492
BDB004492
|
US8618158, Ncl-00016659
N#Cc1ccc(CN2C(=O)c3cccc(Cl)c3C2(OCC2(COC(=O)CCC(=O)O)CC2)c2ccc(Cl)cc2)cc1
|
C31H26Cl2N2O6 593.463000 |
KVYQKFCGNUBIIU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111569; PubChem:CID58433772
|
Local ready
Direct docking supported
|
|
E3L004493
BDB004493
|
US8618158, Ncl-00016653
O=C(O)CCC(=O)OCC1(COC2(c3ccc(Cl)cc3)c3c(Cl)cccc3C(=O)N2Cc2ccc(Br)cc2)CC1
|
C30H26BrCl2NO6 647.349000 |
PNBMTSWQBLBZDE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111570; PubChem:CID58433797
|
Local ready
Direct docking supported
|
|
E3L004494
BDB004494
|
BDBM111571
Cc1ccc(CN2C(=O)c3ccccc3C2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
|
C27H26ClNO3 447.962000 |
VDXUMNSICCELMX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111571; PubChem:CID51350787
|
Local ready
Direct docking supported
|
|
E3L004495
BDB004495
|
BDBM111572
COc1ccc(CN2C(=O)c3ccccc3C2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
|
C27H26ClNO4 463.961000 |
UINYFDYJACQYJK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111572; PubChem:CID51350892
|
Local ready
Direct docking supported
|
|
E3L004496
BDB004496
|
US8618158, Ncl-00016895
C=C(CO)COC1(c2ccc(Cl)cc2)c2ccccc2C(=O)N1Cc1ccc([N+](=O)[O-])cc1
|
C25H21ClN2O5 464.905000 |
JUUBWCLTJHFFON-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111573; PubChem:CID58433782
|
Local ready
Direct docking supported
|
|
E3L004497
BDB004497
|
US8618158, Ncl-00016896
O=C1c2ccccc2C(OCC2(CO)CC2)(c2ccc(F)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C26H23FN2O5 462.477000 |
IMSAUDJGAFQJKH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111574; PubChem:CID58433786
|
Local ready
Direct docking supported
|
|
E3L004498
BDB004498
|
US8618158, Ncl-00016897
O=Nc1ccc(CN2C(=O)c3ccc(F)c(Cl)c3C2(O)c2ccc(Cl)cc2)cc1
|
C21H13Cl2FN2O3 431.250000 |
UOFQLFRBFHZASU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM111575; PubChem:CID58433813
|
Local ready
Direct docking supported
|
|
E3L004499
BDB004499
|
BDBM112735
CC1(C)N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C26H28Cl2FN3O3 520.432000 |
OWIHIJVRYXBFOS-KMTOBGAYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM112735; PubChem:CID71023085
|
Local ready
Direct docking supported
|
|
E3L004500
BDB004500
|
BDBM112736
O=C(NC1CCC(O)CC1)[C@@H]1NC2(CCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C28H30Cl2FN3O3 546.470000 |
HQXQIUHXDOQUSV-NVCNRFTOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112736
|
Local ready
Direct docking supported
|