| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L004501
BDB004501
|
BDBM112737
O=C(NC1CCC(O)CC1)[C@@H]1NC2(CCCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C30H34Cl2FN3O3 574.524000 |
UVWMOYGSAUBCGS-NGYPPSJLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112737
|
Local ready
Direct docking supported
|
|
E3L004502
BDB004502
|
BDBM112738
O=C(NC1CCC(O)CC1)[C@@H]1NC[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C24H24Cl2FN3O3 492.378000 |
QTYORMVOOUGMHF-ACHCXRFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM112738; PubChem:CID71023097
|
Local ready
Direct docking supported
|
|
E3L004503
BDB004503
|
BDBM112739
CCC1(CC)N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C28H33Cl2FN4O3 563.501000 |
ORGYNUKDWVRYBJ-ZQIDGUAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM112739; PubChem:CID71023185
|
Local ready
Direct docking supported
|
|
E3L004504
BDB004504
|
BDBM112740
O=C(NCCN1CCOCC1)[C@@H]1NC2(CCC(F)(F)CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C29H31Cl2F3N4O3 611.492000 |
DUUKXUBPZCGIEL-IQANXLHVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112740
|
Local ready
Direct docking supported
|
|
E3L004505
BDB004505
|
BDBM112741
O=C(NCCN1CCOCC1)[C@@H]1NC2(CCC(F)(F)CC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C29H31Cl2F3N4O3 611.492000 |
DUUKXUBPZCGIEL-KNAJXNNHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112741
|
Local ready
Direct docking supported
|
|
E3L004506
BDB004506
|
BDBM112742
O=C(NC1CCC(O)CC1)[C@@H]1NC2(CCC(F)(F)CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C29H30Cl2F3N3O3 596.477000 |
FQKYDCNRORPEMV-LUEMUNKUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112742
|
Local ready
Direct docking supported
|
|
E3L004507
BDB004507
|
BDBM112743
O=C(NC1CCC(O)CC1)[C@@H]1NC2(CCOCC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C28H30Cl2FN3O4 562.469000 |
PIRIGUPRWKOENE-IOOCNGBKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112743
|
Local ready
Direct docking supported
|
|
E3L004508
BDB004508
|
BDBM112744
O=C(NC1CCC(O)CC1)[C@@H]1NC2(CCOCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C28H30Cl2FN3O4 562.469000 |
PIRIGUPRWKOENE-NVCNRFTOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112744
|
Local ready
Direct docking supported
|
|
E3L004509
BDB004509
|
BDBM112745
O=C(NCCN1CCOCC1)[C@@H]1NC2(CCOCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C28H31Cl2FN4O4 577.484000 |
GUSHNQAWPAYFDT-ZQIDGUAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112745
|
Local ready
Direct docking supported
|
|
E3L004510
BDB004510
|
BDBM112746
CNC(=O)[C@@H]1NC2(CCNCC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C23H23Cl2FN4O2 477.367000 |
HVIFZQHAQKSDBI-GWJPWWOOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112746
|
Local ready
Direct docking supported
|
|
E3L004511
BDB004511
|
BDBM112747
CNC(=O)[C@@H]1NC2(CCNCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C23H23Cl2FN4O2 477.367000 |
HVIFZQHAQKSDBI-GEQKSPFYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112747
|
Local ready
Direct docking supported
|
|
E3L004512
BDB004512
|
BDBM112748
O=C(NCCN1CCOCC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C29H33Cl2FN4O3 575.512000 |
ZULOPCMLZWFEKU-ZLZBJJAKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112748
|
Local ready
Direct docking supported
|
|
E3L004513
BDB004513
|
BDBM112749
CNC(=O)[C@@H]1NC2(CCN(C)CC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C24H25Cl2FN4O2 491.394000 |
APXGCNZUGJHYPE-NRYAXDJKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112749
|
Local ready
Direct docking supported
|
|
E3L004514
BDB004514
|
BDBM112750
CNC(=O)[C@@H]1NC2(CCN(C)CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C24H25Cl2FN4O2 491.394000 |
APXGCNZUGJHYPE-MFSJNOQSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112750
|
Local ready
Direct docking supported
|
|
E3L004515
BDB004515
|
BDBM112751
CNC(=O)[C@@H]1NC2(CCN(C(C)=O)CC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C25H25Cl2FN4O3 519.404000 |
REHJJNQNQSNLAN-HWHXTQLESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112751
|
Local ready
Direct docking supported
|
|
E3L004516
BDB004516
|
BDBM112752
CNC(=O)[C@@H]1NC2(CCN(C(C)=O)CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C25H25Cl2FN4O3 519.404000 |
REHJJNQNQSNLAN-PIBDYAPNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112752
|
Local ready
Direct docking supported
|
|
E3L004517
BDB004517
|
BDBM112753
CS(=O)(=O)CCNC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C26H28Cl2FN3O4S 568.498000 |
IHBAUPOBPNAPEK-UNIVCBNLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112753
|
Local ready
Direct docking supported
|
|
E3L004518
BDB004518
|
BDBM112754
CNC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C24H24Cl2FN3O2 476.379000 |
LHBZDASUSDFFIL-MFSJNOQSSA-N | Q00987, Q96SW2 | E3 ubiquitin-protein ligase Mdm2, Protein cereblon |
BindingDB
BindingDB:BDBM112754
|
Local ready
Direct docking supported
|
|
E3L004519
BDB004519
|
BDBM112755
CS(=O)(=O)CCN1CCC(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C31H37Cl2FN4O4S 651.632000 |
DJKVIZGHBJETHE-ZRLKGHKBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112755
|
Local ready
Direct docking supported
|
|
E3L004520
BDB004520
|
BDBM112757
O=C(O)CCCNC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C27H28Cl2FN3O4 548.442000 |
FYGISHSSTLYWEA-VBANMALSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM112757
|
Local ready
Direct docking supported
|