| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L049141
BDB049141
|
BDBM50234672
CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(C(C)C)cc1
|
C25H29ClN6O2 481.000000 |
TXPYUZYXOTUIHL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234672; PubChem:CID137658881
|
Local ready
Direct docking supported
|
|
E3L049142
BDB049142
|
BDBM50234673
CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(Cl)cc1
|
C22H22Cl2N6O2 473.364000 |
BCFYSDRYJKVTJC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234673; PubChem:CID137657895
|
Local ready
Direct docking supported
|
|
E3L049143
BDB049143
|
BDBM50234674
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1
|
C24H24Cl2N6O2 499.402000 |
JBVUBUHDQUZJTO-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234674; PubChem:CID137644080
|
Local ready
Direct docking supported
|
|
E3L049144
BDB049144
|
BDBM50234675
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCCCC1)c1nnnn1-c1cccc(Oc2ccccc2)c1
|
C30H29ClN6O3 557.054000 |
FYCOPVLIRJPUPS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234675; PubChem:CID137654113
|
Local ready
Direct docking supported
|
|
E3L049145
BDB049145
|
BDBM50234676
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCC1)c1nnnn1-c1cccc(Oc2ccccc2)c1
|
C28H25ClN6O3 529.000000 |
BUDGICYOEPITJV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234676; PubChem:CID137651117
|
Local ready
Direct docking supported
|
|
E3L049146
BDB049146
|
BDBM50234677
CCCCCNC(c1c(C(=O)OCC)[nH]c2cc(Cl)ccc12)c1nnnn1Cc1ccc(OCc2ccccc2F)cc1
|
C32H34ClFN6O3 605.114000 |
DCQMGZWNCLHCIV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234677; PubChem:CID137655392
|
Local ready
Direct docking supported
|
|
E3L049147
BDB049147
|
BDBM50234678
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCC1)c1nnnn1-c1cccc(OCc2ccccc2)c1
|
C31H31ClN6O3 571.081000 |
TVJBWILQPHHDJE-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234678; PubChem:CID137662288
|
Local ready
Direct docking supported
|
|
E3L049148
BDB049148
|
BDBM50234679
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(C(C)C)cc1
|
C29H35ClN6O2 535.092000 |
RBBJXDWOGDHMSP-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234679; PubChem:CID137645068
|
Local ready
Direct docking supported
|
|
E3L049149
BDB049149
|
BDBM50234680
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1
|
C26H28Cl2N6O2 527.456000 |
CAMQOPRFLNGXAS-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234680; PubChem:CID137658613
|
Local ready
Direct docking supported
|
|
E3L049150
BDB049150
|
BDBM50234681
CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1Cc1ccc(OCc2ccccc2F)cc1
|
C30H30ClFN6O3 577.060000 |
GPPNNHAMNOFOTG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50234681; PubChem:CID137647880
|
Local ready
Direct docking supported
|
|
E3L049151
BDB049151
|
BDBM50234682
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCc1ccc(Cl)cc1)c1nnnn1Cc1ccc(OCc2ccccc2Br)cc1
|
C32H25BrCl2N6O3 692.401000 |
DVNUSPAFPVAMGN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234682; PubChem:CID137659676
|
Local ready
Direct docking supported
|
|
E3L049152
BDB049152
|
BDBM50234683
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2Br)cc1
|
C32H32BrClN6O3 664.004000 |
WVNSBUAKYBQBDP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234683; PubChem:CID137661363
|
Local ready
Direct docking supported
|
|
E3L049153
BDB049153
|
BDBM50234684
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2Cl)cc1
|
C32H32Cl2N6O3 619.553000 |
QKDVXPIFJKIYIF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234684; PubChem:CID137635847
|
Local ready
Direct docking supported
|
|
E3L049154
BDB049154
|
BDBM50234685
CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(OCc2ccc(Br)cc2)cc1
|
C29H28BrClN6O3 623.939000 |
PDHIXESMZKXDQO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234685; PubChem:CID137642818
|
Local ready
Direct docking supported
|
|
E3L049155
BDB049155
|
BDBM50234686
CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(OCc2c(Cl)cccc2Cl)cc1
|
C29H27Cl3N6O3 613.933000 |
XSKYKMLHOBETHJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234686; PubChem:CID137652895
|
Local ready
Direct docking supported
|
|
E3L049156
BDB049156
|
BDBM50234687
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(OCc2c(Cl)cccc2Cl)cc1
|
C31H29Cl3N6O3 639.971000 |
GGCQQTXHIWYNCC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234687; PubChem:CID137638774
|
Local ready
Direct docking supported
|
|
E3L049157
BDB049157
|
BDBM50234688
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCC1)c1nnnn1-c1ccc(OCc2ccccc2Br)cc1
|
C28H24BrClN6O3 607.896000 |
XXGYCJQWRSZZPH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234688; PubChem:CID137648552
|
Local ready
Direct docking supported
|
|
E3L049158
BDB049158
|
BDBM50234689
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(OCc2ccccc2Br)cc1
|
C31H30BrClN6O3 649.977000 |
PRTXKOFGIJGYMI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234689; PubChem:CID137658063
|
Local ready
Direct docking supported
|
|
E3L049159
BDB049159
|
BDBM50234690
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NC1C2CC3CC(C2)CC1C3)c1nnnn1-c1ccc(OCc2ccccc2Br)cc1
|
C34H32BrClN6O3 688.026000 |
FCUZENQVKLSHDD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234690; PubChem:CID137642157
|
Local ready
Direct docking supported
|
|
E3L049160
BDB049160
|
BDBM50234691
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCC1)c1nnnn1-c1ccc(OCc2ccccc2)cc1
|
C29H27ClN6O3 543.027000 |
BFPVZAUXDOYWFB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50234691; PubChem:CID137646423
|
Local ready
Direct docking supported
|