| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L050401
BDB050401
|
BDBM50266881
CCN(CC)CCNC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
|
C31H30Cl2FN5O 578.519000 |
QZFQCRCJNWSXST-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50266881; PubChem:CID137654973
|
Local ready
Direct docking supported
|
|
E3L050402
BDB050402
|
BDBM50266882
O=C(O)CCC(=O)OCCCCCCOC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
|
C35H32Cl2FN3O6 680.560000 |
WJVRARWEIGXDLS-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266882; PubChem:CID137647053
|
Local ready
Direct docking supported
|
|
E3L050403
BDB050403
|
BDBM50266883
O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2ccccc2Br)cc1
|
C32H22BrClFN3O3 630.901000 |
UUIUQZOIVINEJE-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50266883; PubChem:CID137631366
|
Local ready
Direct docking supported
|
|
E3L050404
BDB050404
|
BDBM50266884
O=C(c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1)N1CCC(N2CCOCC2)CC1
|
C34H32Cl2FN5O2 632.567000 |
WRMRJBLEOQAWDK-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266884; PubChem:CID137645614
|
Local ready
Direct docking supported
|
|
E3L050405
BDB050405
|
BDBM50266885
O=C(OCCN1CCOCC1)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
|
C31H27Cl2FN4O3 593.486000 |
NARYQSBNVNMWTO-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50266885; PubChem:CID137650518
|
Local ready
Direct docking supported
|
|
E3L050406
BDB050406
|
BDBM50266894
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(F)c(F)c1
|
C27H19ClF3N3O2 509.915000 |
LYJZDVDOCQJVTL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266894; PubChem:CID137634336
|
Local ready
Direct docking supported
|
|
E3L050407
BDB050407
|
BDBM50266895
O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2cc(F)cc(F)c2)cc1
|
C32H21ClF3N3O3 587.985000 |
ILPHHBNVUQDYOW-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50266895; PubChem:CID137642328
|
Local ready
Direct docking supported
|
|
E3L050408
BDB050408
|
BDBM50266896
O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2cc(F)c(F)c(F)c2)cc1
|
C32H20ClF4N3O3 605.975000 |
GCXIQFYOGSTRFW-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50266896; PubChem:CID137655254
|
Local ready
Direct docking supported
|
|
E3L050409
BDB050409
|
BDBM50266897
O=C(NCc1ccc(F)c(F)c1)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
|
C32H21Cl2F3N4O 605.447000 |
LHRBZVKCDQBOLL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266897; PubChem:CID137634453
|
Local ready
Direct docking supported
|
|
E3L050410
BDB050410
|
BDBM50266898
CCOC(=O)C1CCN(C(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccc(F)cc3)ncn2Cc2ccc(Cl)cc2)CC1
|
C33H29Cl2FN4O3 619.524000 |
WTLDZEUFKXXDSA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266898; PubChem:CID137655568
|
Local ready
Direct docking supported
|
|
E3L050411
BDB050411
|
BDBM50266899
O=C(Nc1ccc(N2CCOCC2)cc1)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
|
C35H28Cl2FN5O2 640.546000 |
YRCIECJQRSXORI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266899; PubChem:CID137660352
|
Local ready
Direct docking supported
|
|
E3L050412
BDB050412
|
BDBM50266900
O=C(NCCN1CCOCC1)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
|
C31H28Cl2FN5O2 592.502000 |
DDNOVUYKZKSFGI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266900; PubChem:CID137646904
|
Local ready
Direct docking supported
|
|
E3L050413
BDB050413
|
BDBM50266901
O=C(OCCCCCCO)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
|
C31H28Cl2FN3O3 580.487000 |
BVUMESFGNHWQSQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266901; PubChem:CID137636017
|
Local ready
Direct docking supported
|
|
E3L050414
BDB050414
|
BDBM50266902
O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2ccc(Cl)c(Cl)c2)cc1
|
C32H21Cl3FN3O3 620.895000 |
PSGZJLOFBOICNP-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50266902; PubChem:CID137657789
|
Local ready
Direct docking supported
|
|
E3L050415
BDB050415
|
BDBM50266903
COC(=O)c1ccc(CNC(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccc(F)cc3)ncn2Cc2ccc(Cl)cc2)cc1
|
C34H25Cl2FN4O3 627.503000 |
LBGDYNOYUVKANA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266903; PubChem:CID137656205
|
Local ready
Direct docking supported
|
|
E3L050416
BDB050416
|
BDBM50266906
CN1CCN(C(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccc(F)cc3)ncn2Cc2ccc(Cl)cc2)CC1
|
C30H26Cl2FN5O 562.476000 |
IIAQNOANTAONEG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50266906; PubChem:CID137660704
|
Local ready
Direct docking supported
|
|
E3L050417
BDB050417
|
BDBM50266942
COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2)c(OC(C)C)c1
|
C25H24Cl2N2O2 455.385000 |
YRGSRFXZNYCJNK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50266942; PubChem:CID10173806
|
Local ready
Direct docking supported
|
|
E3L050418
BDB050418
|
BDBM50267046
O=C(O)C[C@@H]1CCCN1c1ccc(OCc2ccc(Cl)cc2Cl)cc1
|
C19H19Cl2NO3 380.271000 |
JHSUHETWKPTXFJ-INIZCTEOSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50267046; PubChem:CID58218630
|
Local ready
Direct docking supported
|
|
E3L050419
BDB050419
|
BDBM50267047
Cc1ccccc1Oc1ccc(N2CCC[C@H]2CC(=O)O)cc1
|
C19H21NO3 311.381000 |
DGKRDKZTRUVURR-INIZCTEOSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50267047; PubChem:CID58218638
|
Local ready
Direct docking supported
|
|
E3L050420
BDB050420
|
BDBM50267295
COC(=O)N[C@H](C(=O)N[C@H](Cc1ccc(-c2ccccn2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N1CCN(Cc2cccc(C(C)(C)O)n2)C1=O)C(C)(C)C)C(C)(C)C
|
C49H65N7O7 864.101000 |
NMNZCBCNNBOZGJ-MTXKAQRHSA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50267295
|
Local ready
Direct docking supported
|