| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L053041
BDB053041
|
BDBM50339174
CC(=O)NCCCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
|
C75H108N16O21 1569.780000 |
QAXJIYGVPJNQKL-BUWQGHJSSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339174; PubChem:CID53321450
|
Local ready
Direct docking supported
|
|
E3L053042
BDB053042
|
BDBM50339175
CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
|
C72H106N18O20 1543.746000 |
XZWISHROARMELS-QVNMLGMESA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339175; PubChem:CID53322773
|
Local ready
Direct docking supported
|
|
E3L053043
BDB053043
|
BDBM50339176
CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
|
C76H108N18O19 1577.807000 |
OLXCWWYOMPHPKD-SLGGZZICSA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50339176; PubChem:CID53322772
|
Local ready
Direct docking supported
|
|
E3L053044
BDB053044
|
BDBM50339177
CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
|
C78H110N18O21 1635.843000 |
GRFZNWPXNWLSQU-SEYRRILQSA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50339177; PubChem:CID53321451
|
Local ready
Direct docking supported
|
|
E3L053045
BDB053045
|
BDBM50339178
CC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
|
C76H107N17O20 1578.791000 |
DUNRBPPAHJWCFO-SLGGZZICSA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50339178; PubChem:CID53322774
|
Local ready
Direct docking supported
|
|
E3L053046
BDB053046
|
BDBM50339179
CC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CO)C(N)=O
|
C77H108N18O20 1605.817000 |
IWIUNJXEPOJENS-DTOIXECGSA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50339179; PubChem:CID53321452
|
Local ready
Direct docking supported
|
|
E3L053047
BDB053047
|
BDBM50339351
Cc1ccc(CN2C(=O)c3ccccc3C2(O[C@H]2C=C[C@@H](O)C2)c2ccc(Cl)cc2)cc1
|
C27H24ClNO3 445.946000 |
GQWCFDLMBXJXGH-ASPAYWPZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339351; PubChem:CID44595320
|
Local ready
Direct docking supported
|
|
E3L053048
BDB053048
|
BDBM50339352
O=C1c2ccccc2C(O[C@H]2C=C[C@@H](O)C2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C26H21ClN2O5 476.916000 |
DQNTZPIUUCMFMC-SGNGHUOJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339352; PubChem:CID44594120
|
Local ready
Direct docking supported
|
|
E3L053049
BDB053049
|
BDBM50339353
O=C1c2ccccc2C(OC/C=C\CO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C25H21ClN2O5 464.905000 |
ZSXCWVPXSODIRG-ARJAWSKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339353; PubChem:CID44595462
|
Local ready
Direct docking supported
|
|
E3L053050
BDB053050
|
BDBM50339354
O=C1c2ccccc2C(OCCCO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C24H21ClN2O5 452.894000 |
GLFIMTCZHOPZNZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339354; PubChem:CID25227971
|
Local ready
Direct docking supported
|
|
E3L053051
BDB053051
|
BDBM50339355
O=C1c2ccccc2C(OCCCCO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C25H23ClN2O5 466.921000 |
MSILRQSPKGOYIL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339355; PubChem:CID25227848
|
Local ready
Direct docking supported
|
|
E3L053052
BDB053052
|
BDBM50339356
N#Cc1ccc(CN2C(=O)c3ccccc3C2(OCCCCO)c2ccc(Cl)cc2)cc1
|
C26H23ClN2O3 446.934000 |
KQQJPJXXBGQESJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339356; PubChem:CID44595461
|
Local ready
Direct docking supported
|
|
E3L053053
BDB053053
|
BDBM50339357
C[C@@H](c1ccc(Cl)cc1)N1C(=O)c2ccccc2C1(OCCCCO)c1ccc(Cl)cc1
|
C26H25Cl2NO3 470.396000 |
FZKHQGZQDYPRLF-MDYZWHIJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339357; PubChem:CID51350512
|
Local ready
Direct docking supported
|
|
E3L053054
BDB053054
|
BDBM50339358
C[C@H](c1ccc(Cl)cc1)N1C(=O)c2ccccc2C1(OCCCCO)c1ccc(Cl)cc1
|
C26H25Cl2NO3 470.396000 |
FZKHQGZQDYPRLF-QOBPCVTDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339358; PubChem:CID44595460
|
Local ready
Direct docking supported
|
|
E3L053055
BDB053055
|
BDBM50339359
O=C1c2ccccc2C(OCCCCO)(c2ccc(Cl)cc2)N1CCc1ccc([N+](=O)[O-])cc1
|
C26H25ClN2O5 480.948000 |
RKRLKEJLWMFRQZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339359; PubChem:CID44595459
|
Local ready
Direct docking supported
|
|
E3L053056
BDB053056
|
BDBM50339360
O=C1c2ccccc2C(OCCCO)(c2ccc(Br)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C24H21BrN2O5 497.345000 |
SZLBLSBKNZZFET-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339360; PubChem:CID51350513
|
Local ready
Direct docking supported
|
|
E3L053057
BDB053057
|
BDBM50339361
O=C1c2ccccc2C(OCCCCO)(c2ccc(Br)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C25H23BrN2O5 511.372000 |
RGEFVEQIUYNOMK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339361; PubChem:CID51350514
|
Local ready
Direct docking supported
|
|
E3L053058
BDB053058
|
BDBM50339362
O=C1c2ccccc2C(OCc2ccc(CO)cc2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C29H23ClN2O5 514.965000 |
GLUMFQWGVLXSJP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339362; PubChem:CID51350515
|
Local ready
Direct docking supported
|
|
E3L053059
BDB053059
|
BDBM50339363
O=C1c2ccccc2C(OC[C@H]2CC[C@H](CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C29H29ClN2O5 521.013000 |
KLCITVQDFSSVKO-FKCXMHPPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50339363
|
Local ready
Direct docking supported
|
|
E3L053060
BDB053060
|
BDBM50339364
O=C1c2ccccc2C(OCc2cccc(CO)c2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C29H23ClN2O5 514.965000 |
XWWSIFDOQOSJOX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339364; PubChem:CID51350650
|
Local ready
Direct docking supported
|