| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L053101
BDB053101
|
BDBM50339406
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1cccc([N+](=O)[O-])c1
|
C21H15ClN2O4 394.814000 |
AYKZZHMSHRUOTP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339406; PubChem:CID51349835
|
Local ready
Direct docking supported
|
|
E3L053102
BDB053102
|
BDBM50339407
O=C1c2ccccc2C(O)(c2ccc(Br)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C21H15BrN2O4 439.265000 |
WRDIZCBMKTVCSR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339407; PubChem:CID51349834
|
Local ready
Direct docking supported
|
|
E3L053103
BDB053103
|
BDBM50339408
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C21H15ClN2O4 394.814000 |
LCURVIQHVBRAPQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339408; PubChem:CID51349704
|
Local ready
Direct docking supported
|
|
E3L053104
BDB053104
|
BDBM50339409
O=C1c2ccccc2C(O)(c2ccc(F)cc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C21H15FN2O4 378.359000 |
JDQPEVSGVBTFKP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339409; PubChem:CID51349703
|
Local ready
Direct docking supported
|
|
E3L053105
BDB053105
|
BDBM50339410
O=C1c2ccccc2C(O)(c2ccccc2)N1Cc1ccc([N+](=O)[O-])cc1
|
C21H16N2O4 360.369000 |
JHLRZXRFMVWOLS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339410; PubChem:CID51349702
|
Local ready
Direct docking supported
|
|
E3L053106
BDB053106
|
BDBM50339411
N#Cc1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C22H15ClN2O2 374.827000 |
QIIYXYNIDJTHQG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339411; PubChem:CID51349701
|
Local ready
Direct docking supported
|
|
E3L053107
BDB053107
|
BDBM50339412
Cc1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C22H18ClNO2 363.844000 |
SBGUDSXIHMTBNZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339412; PubChem:CID51349700
|
Local ready
Direct docking supported
|
|
E3L053108
BDB053108
|
BDBM50339413
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccc(I)cc1
|
C21H15ClINO2 475.713000 |
UDZDEVMPNJUMBO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339413; PubChem:CID51349699
|
Local ready
Direct docking supported
|
|
E3L053109
BDB053109
|
BDBM50339414
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccc(Br)cc1
|
C21H15BrClNO2 428.713000 |
QAMBGJZBFAREOH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339414; PubChem:CID51349698
|
Local ready
Direct docking supported
|
|
E3L053110
BDB053110
|
BDBM50339415
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccc(Cl)cc1
|
C21H15Cl2NO2 384.262000 |
DGWNHIXOANURKW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339415; PubChem:CID51349563
|
Local ready
Direct docking supported
|
|
E3L053111
BDB053111
|
BDBM50339416
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccc(F)cc1
|
C21H15ClFNO2 367.807000 |
BMDQHMWITGBSNM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339416; PubChem:CID51349562
|
Local ready
Direct docking supported
|
|
E3L053112
BDB053112
|
3-(4-Chlorophenyl)-3-hydroxy-2-benzylisoindolin-1-one
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccccc1
|
C21H16ClNO2 349.817000 |
IVVYITXRAYWUAQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339417; PubChem:CID3608080
|
Local ready
Direct docking supported
|
|
E3L053113
BDB053113
|
3-(4-Chlorophenyl)-3-hydroxy-2-propylisoindolin-1-one
CCCN1C(=O)c2ccccc2C1(O)c1ccc(Cl)cc1
|
C17H16ClNO2 301.773000 |
MIDWSIDODUTCGG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339418; PubChem:CID51349561
|
Local ready
Direct docking supported
|
|
E3L053114
BDB053114
|
BDBM50339419
CSc1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C22H18ClNO2S 395.911000 |
WGSKGBMJRSMLNM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339419; PubChem:CID51349971
|
Local ready
Direct docking supported
|
|
E3L053115
BDB053115
|
BDBM50339420
C[S+]([O-])c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C22H18ClNO3S 411.910000 |
NQXKIOZJPCCROR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339420; PubChem:CID51349972
|
Local ready
Direct docking supported
|
|
E3L053116
BDB053116
|
BDBM50339421
CS(=O)(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C22H18ClNO4S 427.909000 |
QAJWJDHDAREANU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339421; PubChem:CID51349973
|
Local ready
Direct docking supported
|
|
E3L053117
BDB053117
|
BDBM50339422
NS(=O)(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C21H17ClN2O4S 428.897000 |
WFQKXJXPGWNYAI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339422; PubChem:CID51349974
|
Local ready
Direct docking supported
|
|
E3L053118
BDB053118
|
BDBM50339423
O=C1c2ccccc2C(O)(c2ccc(Cl)cc2)N1Cc1ccc(C(F)(F)F)cc1
|
C22H15ClF3NO2 417.814000 |
RVBHFDCVFGBLNI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339423; PubChem:CID51349975
|
Local ready
Direct docking supported
|
|
E3L053119
BDB053119
|
BDBM50339424
COC(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C23H18ClNO4 407.853000 |
YQGYZGTXNKOHHM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339424; PubChem:CID51349976
|
Local ready
Direct docking supported
|
|
E3L053120
BDB053120
|
BDBM50339425
O=C(O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
|
C22H16ClNO4 393.826000 |
ZPVWVZMIDHYDQP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50339425; PubChem:CID51350114
|
Local ready
Direct docking supported
|