| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L058721
BDB058721
|
BDBM50515628
CC1(C)[C@H]2CC[C@@]1(C)C(NC(=O)C(c1c(C(=O)O)[nH]c3cc(Cl)ccc13)N(C=O)Cc1ccc(OCc3ccc(Br)cc3)cc1)C2
|
C36H37BrClN3O5 707.065000 |
GEKPZAJRCLIUJV-CAIWFWNLSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50515628
|
Local ready
Direct docking supported
|
|
E3L058722
BDB058722
|
BDBM50515629
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(OCc2ccsc2)cc1
|
C30H32ClN3O5S 582.122000 |
UAJAFTNTZMVJLS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515629; PubChem:CID155559974
|
Local ready
Direct docking supported
|
|
E3L058723
BDB058723
|
BDBM50515630
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(NCc2ccc(Br)cc2)cc1
|
C30H30BrClN4O4 625.951000 |
PUBZGTJJOHSJNS-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515630; PubChem:CID155568384
|
Local ready
Direct docking supported
|
|
E3L058724
BDB058724
|
BDBM50515631
CC(C)(C)NC(=O)C(c1c(C(=O)NCCN2CCOCC2)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2Br)cc1
|
C36H41BrClN5O5 739.111000 |
QTVLYWNOEMLZCU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515631; PubChem:CID155563099
|
Local ready
Direct docking supported
|
|
E3L058725
BDB058725
|
BDBM50515632
CC(C)(C)NC(=O)C(NCc1ccc(OCc2ccccc2Br)cc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
|
C29H29BrClN3O4 598.925000 |
NNPRLGPHUYKKSB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515632; PubChem:CID155511790
|
Local ready
Direct docking supported
|
|
E3L058726
BDB058726
|
BDBM50515633
O=CN(CCc1ccccc1)C(C(=O)NC12CC3CC(CC(C3)C1)C2)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
|
C30H32ClN3O4 534.056000 |
WVLFJQVVVNIWHF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515633; PubChem:CID155559422
|
Local ready
Direct docking supported
|
|
E3L058727
BDB058727
|
BDBM50515634
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)CCCN1CCOCC1
|
C23H31ClN4O5 478.977000 |
UZAMNCFPDZQWGU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515634; PubChem:CID155526750
|
Local ready
Direct docking supported
|
|
E3L058728
BDB058728
|
BDBM50515635
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(F)cc2)cc1
|
C30H29ClFN3O5 566.029000 |
CRRNQUILJLKVMZ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515635; PubChem:CID155521620
|
Local ready
Direct docking supported
|
|
E3L058729
BDB058729
|
BDBM50515636
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2F)cc1
|
C30H29ClFN3O5 566.029000 |
XTIBFYHFGPXURQ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515636; PubChem:CID155526905
|
Local ready
Direct docking supported
|
|
E3L058730
BDB058730
|
BDBM50515637
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2C(F)(F)F)cc1
|
C31H29ClF3N3O5 616.036000 |
VAGHMOOTYBDLTJ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515637; PubChem:CID155546509
|
Local ready
Direct docking supported
|
|
E3L058731
BDB058731
|
BDBM50515638
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCC2CCCCC2)cc1
|
C30H36ClN3O5 554.087000 |
YQQCLJWZNMNSBU-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515638; PubChem:CID155554714
|
Local ready
Direct docking supported
|
|
E3L058732
BDB058732
|
BDBM50515639
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccn2)cc1
|
C29H29ClN4O5 549.027000 |
WZINJLCGRWELCA-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515639; PubChem:CID155561097
|
Local ready
Direct docking supported
|
|
E3L058733
BDB058733
|
BDBM50515640
CC1(C)[C@H]2CC[C@@]1(C)C(NC(=O)C(c1c(C(=O)O)[nH]c3cc(Cl)ccc13)N(C=O)Cc1ccc(OCc3ccccc3Br)cc1)C2
|
C36H37BrClN3O5 707.065000 |
OMUYGOGGWRFGKD-CAIWFWNLSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50515640
|
Local ready
Direct docking supported
|
|
E3L058734
BDB058734
|
BDBM50515641
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2Br)cc1
|
C30H29BrClN3O5 626.935000 |
ZYUXHGXGYZXKTO-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515641; PubChem:CID155522131
|
Local ready
Direct docking supported
|
|
E3L058735
BDB058735
|
BDBM50515642
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2)cc1
|
C30H30ClN3O5 548.039000 |
PDKBKVLVVGVSIT-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515642; PubChem:CID155558664
|
Local ready
Direct docking supported
|
|
E3L058736
BDB058736
|
BDBM50515643
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCCc2ccccc2)cc1
|
C31H32ClN3O5 562.066000 |
JVSRFYKFOWRYEA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515643; PubChem:CID155566670
|
Local ready
Direct docking supported
|
|
E3L058737
BDB058737
|
BDBM50515644
CC(=O)N(Cc1ccc(OCc2ccccc2)cc1)C(C(=O)NC12CC3CC(CC(C3)C1)C2)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
|
C37H38ClN3O5 640.180000 |
MWAGCBXSLRYTRA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515644; PubChem:CID155542750
|
Local ready
Direct docking supported
|
|
E3L058738
BDB058738
|
BDBM50515645
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Br)cc2)cc1
|
C30H29BrClN3O5 626.935000 |
DUSPZYIRSWEGJH-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515645; PubChem:CID155541655
|
Local ready
Direct docking supported
|
|
E3L058739
BDB058739
|
BDBM50515646
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(NCc2ccc(Br)cc2)cc1
|
C32H34BrClN4O4 654.005000 |
CMKXDEWFJXQZDF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515646; PubChem:CID155566162
|
Local ready
Direct docking supported
|
|
E3L058740
BDB058740
|
BDBM50515647
O=CN(CCc1ccccc1)C(C(=O)NCCc1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
|
C28H26ClN3O4 503.986000 |
QXSNPPSAVDESNR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515647; PubChem:CID155532959
|
Local ready
Direct docking supported
|