| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L058701
BDB058701
|
BDBM50515608
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cccc(Br)c2)cc1
|
C30H29BrClN3O5 626.935000 |
MYXNSCNOAFRTII-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515608; PubChem:CID155530377
|
Local ready
Direct docking supported
|
|
E3L058702
BDB058702
|
BDBM50515609
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1cc(F)c(OCc2ccccc2)c(F)c1
|
C30H28ClF2N3O5 584.019000 |
DUGKBXMLGCLZHO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515609; PubChem:CID155522379
|
Local ready
Direct docking supported
|
|
E3L058703
BDB058703
|
BDBM50515610
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(C#N)cc2)cc1
|
C31H29ClN4O5 573.049000 |
YTLMZZSMAWUXCZ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515610; PubChem:CID155532432
|
Local ready
Direct docking supported
|
|
E3L058704
BDB058704
|
BDBM50515611
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cc(F)cc(F)c2)cc1
|
C30H28ClF2N3O5 584.019000 |
UFEXLJCEZMUACH-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515611; PubChem:CID155548484
|
Local ready
Direct docking supported
|
|
E3L058705
BDB058705
|
BDBM50515612
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cccc(Cl)c2)cc1
|
C30H29Cl2N3O5 582.484000 |
WGLOAACVPHQWFB-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515612; PubChem:CID155564869
|
Local ready
Direct docking supported
|
|
E3L058706
BDB058706
|
BDBM50515613
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Cl)cc2Cl)cc1
|
C30H28Cl3N3O5 616.929000 |
FENGJNVDRAAJEM-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515613; PubChem:CID155541314
|
Local ready
Direct docking supported
|
|
E3L058707
BDB058707
|
BDBM50515614
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2c(Cl)cccc2Cl)cc1
|
C30H28Cl3N3O5 616.929000 |
BFRNRLIDPDCUSK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515614; PubChem:CID155523178
|
Local ready
Direct docking supported
|
|
E3L058708
BDB058708
|
BDBM50515615
CC(C)(C)NC(=O)[C@@H](c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2Br)cc1
|
C30H29BrClN3O5 626.935000 |
ZYUXHGXGYZXKTO-HHHXNRCGSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515615; PubChem:CID155558272
|
Local ready
Direct docking supported
|
|
E3L058709
BDB058709
|
BDBM50515616
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(I)cc2)cc1
|
C30H29ClIN3O5 673.935000 |
WVMYAEZRIHNOKR-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515616; PubChem:CID155524001
|
Local ready
Direct docking supported
|
|
E3L058710
BDB058710
|
BDBM50515617
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cccc(I)c2)cc1
|
C30H29ClIN3O5 673.935000 |
DBOBUBALPHWFKQ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515617; PubChem:CID155565604
|
Local ready
Direct docking supported
|
|
E3L058711
BDB058711
|
BDBM50515618
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2I)cc1
|
C30H29ClIN3O5 673.935000 |
UCBNIVFIPPVRSX-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515618; PubChem:CID155523379
|
Local ready
Direct docking supported
|
|
E3L058712
BDB058712
|
BDBM50515619
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1
|
C32H28ClF6N3O5 684.033000 |
IUTLFZDIWVAHED-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515619; PubChem:CID155522186
|
Local ready
Direct docking supported
|
|
E3L058713
BDB058713
|
BDBM50515620
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1
|
C36H34ClN3O5 624.137000 |
OVFVSTOSPLYTQE-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515620; PubChem:CID155554511
|
Local ready
Direct docking supported
|
|
E3L058714
BDB058714
|
BDBM50515621
COc1cccc(COc2ccc(CN(C=O)C(C(=O)NC(C)(C)C)c3c(C(=O)O)[nH]c4cc(Cl)ccc34)cc2)c1
|
C31H32ClN3O6 578.065000 |
PNXNUCBDUGINPJ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515621; PubChem:CID155523298
|
Local ready
Direct docking supported
|
|
E3L058715
BDB058715
|
BDBM50515622
COc1cccc(COc2ccc(CN(C=O)C(C(=O)NC(C)(C)C)c3c(C(=O)O)[nH]c4cc(Cl)ccc34)cc2)c1OC
|
C32H34ClN3O7 608.091000 |
YCDDWQVVYUTNJQ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515622; PubChem:CID155569673
|
Local ready
Direct docking supported
|
|
E3L058716
BDB058716
|
BDBM50515623
Cc1ccc(COc2ccc(CN(C=O)C(C(=O)NC(C)(C)C)c3c(C(=O)O)[nH]c4cc(Cl)ccc34)cc2)cc1
|
C31H32ClN3O5 562.066000 |
ACUIQAXLSNBKIL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515623; PubChem:CID155517444
|
Local ready
Direct docking supported
|
|
E3L058717
BDB058717
|
BDBM50515624
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OC2CCCC2)cc1
|
C28H32ClN3O5 526.033000 |
QDCOYXTYPWZZAC-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515624; PubChem:CID155529926
|
Local ready
Direct docking supported
|
|
E3L058718
BDB058718
|
BDBM50515625
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccncc2)cc1
|
C29H29ClN4O5 549.027000 |
JKVPBDPVHVUNQG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515625; PubChem:CID155518117
|
Local ready
Direct docking supported
|
|
E3L058719
BDB058719
|
BDBM50515626
CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)CCc1ccc(OCc2ccc(Br)cc2)cc1
|
C31H31BrClN3O5 640.962000 |
ACOCPUKWQPWQJW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50515626; PubChem:CID155522380
|
Local ready
Direct docking supported
|
|
E3L058720
BDB058720
|
BDBM50515627
O=CN(Cc1ccc(OCc2ccccc2Br)cc1)C(C(=O)NC1C2CC3CC(C2)CC1C3)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
|
C36H35BrClN3O5 705.049000 |
QUKGMHKFHDSFBM-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50515627; PubChem:CID155555639
|
Local ready
Direct docking supported
|