| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L060001
BDB060001
|
BDBM50542055
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)nc2)cn1
|
C26H24N6O 436.519000 |
ZJGMOHOOSGHFMJ-RUZDIDTESA-N | Q09472, Q92793 | Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50542055; PubChem:CID146014966
|
Local ready
Direct docking supported
|
|
E3L060002
BDB060002
|
BDBM50542056
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)cn2)cn1
|
C26H24N6O 436.519000 |
FWUKETSVGXRKEY-RUZDIDTESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50542056; PubChem:CID156013603
|
Local ready
Direct docking supported
|
|
E3L060003
BDB060003
|
BDBM50542057
Cn1cc(-c2cnc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)cn2)cn1
|
C25H23N7O 437.507000 |
BNJIGTSAPAJMFC-XMMPIXPASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50542057; PubChem:CID156013232
|
Local ready
Direct docking supported
|
|
E3L060004
BDB060004
|
BDBM50542058
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)nn2)cn1
|
C25H23N7O 437.507000 |
CDYZSDIRBQXFGC-XMMPIXPASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50542058; PubChem:CID156017058
|
Local ready
Direct docking supported
|
|
E3L060005
BDB060005
|
BDBM50542059
Cn1cc(-c2ncc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)cn2)cn1
|
C25H23N7O 437.507000 |
SHAJSBACPAWTQT-HSZRJFAPSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50542059; PubChem:CID156020071
|
Local ready
Direct docking supported
|
|
E3L060006
BDB060006
|
BDBM50542060
C[C@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(C)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C27H26N6O 450.546000 |
SEDFZSHSBUXKAC-NIYFSFCBSA-N | Q09472, Q92793 | Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50542060; PubChem:CID146014965
|
Local ready
Direct docking supported
|
|
E3L060007
BDB060007
|
BDBM50542268
CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2CC12CCOCC2
|
C30H34BrN3O4 580.523000 |
WEUSBBSVDABQAW-JDEXWRGDSA-N | P98170 | E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM50542268; PubChem:CID156014703
|
Local ready
Direct docking supported
|
|
E3L060008
BDB060008
|
BDBM50542269
CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(C#N)n(-c3ccccc3C#N)c3ccccc23)c2ccccc2CC12CCOCC2
|
C35H34N6O3 586.696000 |
RHHHIZVXCBEMRY-SZGIACGNSA-N | P98170 | E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM50542269; PubChem:CID156009481
|
Local ready
Direct docking supported
|
|
E3L060009
BDB060009
|
BDBM50542270
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C29H35Cl2FN4O3 577.528000 |
YTBYOWZWBDYLQF-ILRKGFAZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50542270; PubChem:CID156018933
|
Local ready
Direct docking supported
|
|
E3L060010
BDB060010
|
BDBM50542271
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C29H34Cl2FN3O3 562.513000 |
IDKAKZRYYDCJDU-LWBDNYSYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50542271
|
Local ready
Direct docking supported
|
|
E3L060011
BDB060011
|
BDBM50542272
Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccccc2Cl)on1
|
C18H20ClN3O4 377.828000 |
UGZKBQSCCGQTLZ-CJNGLKHVSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50542272; PubChem:CID57382178
|
Local ready
Direct docking supported
|
|
E3L060012
BDB060012
|
BDBM50542273
O=C(O)[C@H]1CCC[C@H]1C(=O)N1CCc2ccccc2[C@H]1CN1C(=O)c2ccccc2C1=O
|
C25H24N2O5 432.476000 |
VLYHLCQLLVPWJM-QHAWAJNXSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50542273; PubChem:CID145958345
|
Local ready
Direct docking supported
|
|
E3L060013
BDB060013
|
BDBM50542274
O=C(O)[C@H]1CCCC[C@H]1C(=O)N1CCc2ccccc2[C@H]1CN1C(=O)CCC1=O
|
C22H26N2O5 398.459000 |
IOTCJAZBVIBCPM-FGTMMUONSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50542274; PubChem:CID145960115
|
Local ready
Direct docking supported
|
|
E3L060014
BDB060014
|
Dyrk1A-IN-3
Cc1cccc(N(C)c2nccc(-c3cnn4ncccc34)n2)c1
|
C18H16N6 316.368000 |
XOBINHQHMGZFDI-UHFFFAOYSA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50543394; PubChem:CID156011155
|
Local ready
Direct docking supported
|
|
E3L060015
BDB060015
|
BDBM50543445
COc1cccc([C@@]2(C34CC5CC(CC(C5)C3)C4)N=C(N)N(C)C2=O)c1
|
C21H27N3O2 353.466000 |
NTEXGYXPUMXCQI-GEYGSZSDSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM50543445; PubChem:CID156021569
|
Local ready
Direct docking supported
|
|
E3L060016
BDB060016
|
BDBM50543446
CN1C(=O)[C@](c2ccccc2)(C23CC4CC(CC(C4)C2)C3)N=C1N
|
C20H25N3O 323.440000 |
BEDDENNXVBITIQ-IJWPFNNMSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM50543446; PubChem:CID156014167
|
Local ready
Direct docking supported
|
|
E3L060017
BDB060017
|
BDBM50543447
CN1C(=O)[C@](c2ccc3ccccc3c2)(C23CC4CC(CC(C4)C2)C3)N=C1N
|
C24H27N3O 373.500000 |
PEZCYCNZDMTLLQ-JJHVHIABSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM50543447; PubChem:CID156017325
|
Local ready
Direct docking supported
|
|
E3L060018
BDB060018
|
BDBM50543448
COc1ccc(C2(C34CC5CC(O)(CC(F)(C5)C3)C4)N=C(N)N(C)C2=O)cc1
|
C21H26FN3O3 387.455000 |
ZTMMGDFSHICYDN-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM50543448; PubChem:CID156021628
|
Local ready
Direct docking supported
|
|
E3L060019
BDB060019
|
BDBM50543449
COc1ccc([C@@]2(C34CC5CC(CC(O)(C5)C3)C4)N=C(N)N(C)C2=O)cc1
|
C21H27N3O3 369.465000 |
NYXCEDBEACLWMP-SCJBTZFISA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM50543449; PubChem:CID156017469
|
Local ready
Direct docking supported
|
|
E3L060020
BDB060020
|
BDBM50543450
COc1ccc(C2(C34CCC(CC3)CC4)N=C(N)N(C)C2=O)cc1
|
C19H25N3O2 327.428000 |
XHLBXTMTHYPYNB-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM50543450; PubChem:CID156011432
|
Local ready
Direct docking supported
|