| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L060781
BDB060781
|
BDBM50568968
Cn1cc(-c2cc3ncnc(Nc4ccc(CC(=O)Nc5cc(C(C)(C)C)nn5C)cc4)c3s2)cn1
|
C26H28N8OS 500.632000 |
CFAOOHPDKFUMTF-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM50568968; PubChem:CID164620237
|
Local ready
Direct docking supported
|
|
E3L060782
BDB060782
|
BDBM50569135
Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H17F3N4O4 458.396000 |
RMWKPNDZZKXTGS-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569135; PubChem:CID164626316
|
Local ready
Direct docking supported
|
|
E3L060783
BDB060783
|
BDBM50569136
Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccc(F)cc23)c1[N+](=O)[O-]
|
C22H16F4N4O4 476.386000 |
KFAZKDQUMWYVLJ-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569136; PubChem:CID164626741
|
Local ready
Direct docking supported
|
|
E3L060784
BDB060784
|
BDBM50569137
Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccc(Cl)cc23)c1[N+](=O)[O-]
|
C22H16ClF3N4O4 492.841000 |
XKHJYDVYLKFERL-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569137; PubChem:CID164612553
|
Local ready
Direct docking supported
|
|
E3L060785
BDB060785
|
BDBM50569138
Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2cc(Cl)ccc23)c1[N+](=O)[O-]
|
C22H16ClF3N4O4 492.841000 |
AVMZCRICWNQQKP-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569138; PubChem:CID164625260
|
Local ready
Direct docking supported
|
|
E3L060786
BDB060786
|
BDBM50569139
Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccc(Br)cc23)c1[N+](=O)[O-]
|
C22H16BrF3N4O4 537.292000 |
PCPBFVDYNYQVIL-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569139; PubChem:CID164624491
|
Local ready
Direct docking supported
|
|
E3L060787
BDB060787
|
BDBM50569140
Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2cc(Br)ccc23)c1[N+](=O)[O-]
|
C22H16BrF3N4O4 537.292000 |
AGHXNHYXTSTKDI-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569140; PubChem:CID164624497
|
Local ready
Direct docking supported
|
|
E3L060788
BDB060788
|
BDBM50569141
Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccc([N+](=O)[O-])cc23)c1[N+](=O)[O-]
|
C22H16F3N5O6 503.393000 |
VYZCVOJLTFWRDL-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569141; PubChem:CID164626245
|
Local ready
Direct docking supported
|
|
E3L060789
BDB060789
|
BDBM50569142
Cc1ccc2c(c1)[C@]1(N[C@@H](C(F)(F)F)[C@H](c3ccccc3)[C@H]1c1onc(C)c1[N+](=O)[O-])C(=O)N2
|
C23H19F3N4O4 472.423000 |
CKXWERFXQNWIFZ-IMLKGASGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569142; PubChem:CID164628924
|
Local ready
Direct docking supported
|
|
E3L060790
BDB060790
|
BDBM50569143
Cc1noc([C@@H]2[C@@H](c3cccc(F)c3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16F4N4O4 476.386000 |
OUDXLVMBBJQOCI-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569143; PubChem:CID164627449
|
Local ready
Direct docking supported
|
|
E3L060791
BDB060791
|
BDBM50569144
Cc1noc([C@@H]2[C@@H](c3ccc(F)cc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16F4N4O4 476.386000 |
UPRZAXNTXICKMR-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569144; PubChem:CID164621622
|
Local ready
Direct docking supported
|
|
E3L060792
BDB060792
|
BDBM50569145
Cc1noc([C@@H]2[C@@H](c3ccccc3Cl)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16ClF3N4O4 492.841000 |
ASNSHBUNUQLUPD-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569145; PubChem:CID164619211
|
Local ready
Direct docking supported
|
|
E3L060793
BDB060793
|
BDBM50569146
Cc1noc([C@@H]2[C@@H](c3ccc(Cl)cc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16ClF3N4O4 492.841000 |
SJBSKTMWEMUCQF-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569146; PubChem:CID164621535
|
Local ready
Direct docking supported
|
|
E3L060794
BDB060794
|
BDBM50569147
Cc1noc([C@@H]2[C@@H](c3ccccc3Br)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16BrF3N4O4 537.292000 |
OLZIQRQJGFDWIR-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569147; PubChem:CID164611535
|
Local ready
Direct docking supported
|
|
E3L060795
BDB060795
|
BDBM50569148
Cc1noc([C@@H]2[C@@H](c3cccc(Br)c3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16BrF3N4O4 537.292000 |
YAVHQYBPJSDLSH-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569148; PubChem:CID164609970
|
Local ready
Direct docking supported
|
|
E3L060796
BDB060796
|
BDBM50569149
Cc1noc([C@@H]2[C@@H](c3ccc(Br)cc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16BrF3N4O4 537.292000 |
OEHIVKUEIRHHSB-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569149; PubChem:CID164628709
|
Local ready
Direct docking supported
|
|
E3L060797
BDB060797
|
BDBM50569150
Cc1noc([C@@H]2[C@@H](c3ccc([N+](=O)[O-])cc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccccc23)c1[N+](=O)[O-]
|
C22H16F3N5O6 503.393000 |
KNZNUPKCTBFXRW-NNNWTRQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569150; PubChem:CID164616403
|
Local ready
Direct docking supported
|
|
E3L060798
BDB060798
|
BDBM50569151
Cc1ccccc1[C@H]1[C@H](C(F)(F)F)N[C@@]2(C(=O)Nc3ccccc32)[C@@H]1c1onc(C)c1[N+](=O)[O-]
|
C23H19F3N4O4 472.423000 |
KLEULYZMLJUWNK-IMLKGASGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569151; PubChem:CID164623589
|
Local ready
Direct docking supported
|
|
E3L060799
BDB060799
|
BDBM50569152
Cc1ccc([C@H]2[C@H](C(F)(F)F)N[C@@]3(C(=O)Nc4ccccc43)[C@@H]2c2onc(C)c2[N+](=O)[O-])cc1
|
C23H19F3N4O4 472.423000 |
OMDXGAAAXFILOG-IMLKGASGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569152; PubChem:CID164618024
|
Local ready
Direct docking supported
|
|
E3L060800
BDB060800
|
BDBM50569153
COc1ccccc1[C@H]1[C@H](C(F)(F)F)N[C@@]2(C(=O)Nc3ccccc32)[C@@H]1c1onc(C)c1[N+](=O)[O-]
|
C23H19F3N4O5 488.422000 |
DRNVAUQVGMZKNO-IMLKGASGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50569153; PubChem:CID164616221
|
Local ready
Direct docking supported
|