| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L061701
BDB061701
|
BDBM50585775
CN1CCC([C@@](C)(O)c2ccc3cnc(Nc4cc(N5CCCC5)ncc4F)cc3n2)CC1
|
C25H31FN6O 450.562000 |
HUNWQLBOLVYRMW-RUZDIDTESA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585775; PubChem:CID166631779
|
Local ready
Direct docking supported
|
|
E3L061702
BDB061702
|
BDBM50585776
CC(C)Nc1cc(Nc2cc3nc([C@](C)(O)C4CCN(C)CC4)ccc3cn2)c(F)cn1
|
C24H31FN6O 438.551000 |
UZQXPHDZFUAMQS-XMMPIXPASA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585776; PubChem:CID166627570
|
Local ready
Direct docking supported
|
|
E3L061703
BDB061703
|
BDBM50585777
CC(C)Oc1cc(Nc2cc3nc([C@](C)(O)C4CCN(C)CC4)ccc3cn2)c(F)cn1
|
C24H30FN5O2 439.535000 |
WLPDYLPFPWPYBC-XMMPIXPASA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585777; PubChem:CID166630123
|
Local ready
Direct docking supported
|
|
E3L061704
BDB061704
|
BDBM50585778
CN1CCC([C@@](C)(O)c2ccc3cnc(Nc4cc(OC5CCC5)ncc4F)cc3n2)CC1
|
C25H30FN5O2 451.546000 |
CLCKDDAPJRHFEN-RUZDIDTESA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585778; PubChem:CID166634189
|
Local ready
Direct docking supported
|
|
E3L061705
BDB061705
|
BDBM50585779
CCc1cc(Nc2cc3nc([C@](C)(O)C4CCN(C)CC4)ccc3cn2)c(F)cn1
|
C23H28FN5O 409.509000 |
QXVWBJROURLRIW-HSZRJFAPSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585779; PubChem:CID166632020
|
Local ready
Direct docking supported
|
|
E3L061706
BDB061706
|
BDBM50585780
CC(C)c1cc(Nc2cc3nc([C@](C)(O)C4CCN(C)CC4)ccc3cn2)c(F)cn1
|
C24H30FN5O 423.536000 |
HRKCERYJQXATNH-XMMPIXPASA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585780; PubChem:CID166632368
|
Local ready
Direct docking supported
|
|
E3L061707
BDB061707
|
BDBM50585781
CN1CCC([C@@](C)(O)c2ccc3cnc(Nc4cc(C(F)(F)F)ncc4F)cc3n2)CC1
|
C22H23F4N5O 449.452000 |
GHNYLVIESIGHDJ-OAQYLSRUSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585781; PubChem:CID162439673
|
Local ready
Direct docking supported
|
|
E3L061708
BDB061708
|
BDBM50585782
CC(C)c1cc(Nc2cc3nc([C@](C)(O)C4CCN(C)CC4)ccc3cn2)c(F)cc1C#N
|
C26H30FN5O 447.558000 |
MOXBYMQBYZTOJA-AREMUKBSSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585782; PubChem:CID166629073
|
Local ready
Direct docking supported
|
|
E3L061709
BDB061709
|
BDBM50585783
CC(C)Oc1cc(Nc2cc3nc([C@](C)(O)C4CCN(C)CC4)ccc3cn2)c(F)cc1C#N
|
C26H30FN5O2 463.557000 |
QRPJDQZOXSLSEK-AREMUKBSSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585783; PubChem:CID166625236
|
Local ready
Direct docking supported
|
|
E3L061710
BDB061710
|
BDBM50585784
CN1CCC([C@@](C)(O)c2ccc3cnc(Nc4cc(C(F)(F)F)c(C#N)cc4F)cc3n2)CC1
|
C24H23F4N5O 473.474000 |
WIQLQHJLURUMAP-HSZRJFAPSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585784; PubChem:CID166632292
|
Local ready
Direct docking supported
|
|
E3L061711
BDB061711
|
BDBM50585785
CN1CCC([C@@](C)(O)c2ccc3cnc(Nc4cc(N5CC6CCC(C5)O6)c(C#N)cc4F)cc3n2)CC1
|
C29H33FN6O2 516.621000 |
PHVGAEJTLZFYTO-UQIPPQJZSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585785; PubChem:CID166625947
|
Local ready
Direct docking supported
|
|
E3L061712
BDB061712
|
BDBM50585786
CN1CCC([C@@](C)(O)c2ccc3cnc(Nc4cc(C(N)=O)ncc4F)cc3n2)CC1
|
C22H25FN6O2 424.480000 |
DDPAPPCCQQJSAP-JOCHJYFZSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM50585786; PubChem:CID166629991
|
Local ready
Direct docking supported
|
|
E3L061713
BDB061713
|
BDBM50586176
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NCCCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)cc4)nc4[nH]ccc34)cn2)C1
|
C40H40N12O7S 832.904000 |
XTSGMNYQSRAKGD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586176
|
Local ready
Direct docking supported
|
|
E3L061714
BDB061714
|
BDBM50586177
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NCCCCOc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)cc4)nc4[nH]ccc34)cn2)C1
|
C40H39N11O8S 833.888000 |
RHRPJQJOBDOJKU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586177
|
Local ready
Direct docking supported
|
|
E3L061715
BDB061715
|
BDBM50586178
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NC5CCN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)cc4)nc4[nH]ccc34)cn2)C1
|
C41H40N12O7S 844.915000 |
QENXNFNQQOSOIZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586178
|
Local ready
Direct docking supported
|
|
E3L061716
BDB061716
|
BDBM50586179
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NCCN5CCN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)cc4)nc4[nH]ccc34)cn2)C1
|
C42H43N13O7S 873.957000 |
PURCRNBCKBOXFH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586179
|
Local ready
Direct docking supported
|
|
E3L061717
BDB061717
|
BDBM50586180
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NCCCCNc5cccc(C6CCC(=O)NC6=O)c5)cc4)nc4[nH]ccc34)cn2)C1
|
C38H41N11O5S 763.885000 |
YMDKCHNRIDZCIK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586180
|
Local ready
Direct docking supported
|
|
E3L061718
BDB061718
|
BDBM50586181
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NCCCCOc5ccc(C6CCC(=O)NC6=O)cc5)cc4)nc4[nH]ccc34)cn2)C1
|
C38H40N10O6S 764.869000 |
JQXUGPKGNONGRJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586181
|
Local ready
Direct docking supported
|
|
E3L061719
BDB061719
|
BDBM50586182
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NCCCCOc5cccc(C6CCC(=O)NC6=O)c5)cc4)nc4[nH]ccc34)cn2)C1
|
C38H40N10O6S 764.869000 |
CXJYSNHTGSVIBV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586182
|
Local ready
Direct docking supported
|
|
E3L061720
BDB061720
|
BDBM50586183
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NC5CCN(c6ccc(C7CCC(=O)NC7=O)cc6)CC5)cc4)nc4[nH]ccc34)cn2)C1
|
C39H41N11O5S 775.896000 |
XKYDUBODDYBCNZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50586183
|
Local ready
Direct docking supported
|