| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L062241
BDB062241
|
BDBM50594933
CN1CC=C(c2cnc(NCC3Cc4cc(F)ccc4O3)c3cncnc23)CC1
|
C22H22FN5O 391.450000 |
HQECZDLCJWLHIF-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594933; PubChem:CID168286204
|
Local ready
Direct docking supported
|
|
E3L062242
BDB062242
|
BDBM50594934
Cc1ncccc1-c1cnc(NCC2Cc3cc(F)ccc3O2)c2nncn12
|
C20H17FN6O 376.395000 |
VTPYFHCXTNEVBS-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594934; PubChem:CID168270648
|
Local ready
Direct docking supported
|
|
E3L062243
BDB062243
|
BDBM50594935
CN1CC=C(c2cnc(NCC3Cc4cc(F)ccc4O3)c3nncn23)CC1
|
C20H21FN6O 380.427000 |
XERCYUXHKUHKGH-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594935; PubChem:CID168297796
|
Local ready
Direct docking supported
|
|
E3L062244
BDB062244
|
BDBM50594936
Cc1ncccc1-c1cnc(NCC2Cc3cc(F)ccc3O2)n2cc(C#N)nc12
|
C22H17FN6O 400.417000 |
NDYGLRJTSMPXDG-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594936; PubChem:CID168295428
|
Local ready
Direct docking supported
|
|
E3L062245
BDB062245
|
BDBM50594937
Cc1cc(-c2cnc(NCC3Cc4cc(F)ccc4O3)n3cc(C#N)nc23)n(C)n1
|
C21H18FN7O 403.421000 |
CSZYOFXLRJGTGC-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594937; PubChem:CID168272326
|
Local ready
Direct docking supported
|
|
E3L062246
BDB062246
|
BDBM50594938
[2H]C([2H])(Nc1ncc(-c2cccnc2C)c(=O)n1C)c1c(F)ccc2c1CCO2
|
C20H19FN4O2 368.408204 |
LLVPYYDXFXKDQC-KBMKNGFXSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594938; PubChem:CID168290256
|
Local ready
Direct docking supported
|
|
E3L062247
BDB062247
|
BDBM50594939
Cc1nc(NCc2c(F)ccc3c2CCO3)sc1-c1ccnn1C
|
C17H17FN4OS 344.415000 |
CWTSSRABGHQCLL-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594939; PubChem:CID168278640
|
Local ready
Direct docking supported
|
|
E3L062248
BDB062248
|
BDBM50594940
Cc1ncccc1-c1sc(NCc2c(F)ccc3c2CCO3)nc1C
|
C19H18FN3OS 355.438000 |
CDFSFPATWOKGHB-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594940; PubChem:CID168273538
|
Local ready
Direct docking supported
|
|
E3L062249
BDB062249
|
BDBM50594941
Cc1nc(NCc2cccc3c2OCO3)sc1-c1ccn(C)n1
|
C16H16N4O2S 328.397000 |
VRBFSPXSSUIMQI-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594941; PubChem:CID126463397
|
Local ready
Direct docking supported
|
|
E3L062250
BDB062250
|
Q7VU9N2UO2
Cc1ncccc1-c1cc2c(n3cnnc13)NCc1c(F)ccc3c1[C@@H](CO3)CO2
|
C22H18FN5O2 403.417000 |
JQBUTSBIFNKJMW-ZDUSSCGKSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594942; PubChem:CID155286052
|
Local ready
Direct docking supported
|
|
E3L062251
BDB062251
|
BDBM50594943
CCOP(=O)(OCC)C(NC(=O)[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)/C=C/c1ccc(-c2ccccc2)cc1)P(=O)(OCC)OCC
|
C39H46N2O8P2 732.751000 |
UDORQAZNJOIXPJ-KXULKXHNSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594943; PubChem:CID168270250
|
Local ready
Direct docking supported
|
|
E3L062252
BDB062252
|
BDBM50594944
CN(C)[C@@H]1CN(C2CCc3cccc(F)c32)C[C@H]1c1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
|
C26H35FN4O2S 486.657000 |
REVJNSVNICWODC-DEWJTGPOSA-N | O75530 | Histone-lysine N-methyltransferase EZH2, Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50594944; PubChem:CID132085619
|
Local ready
Direct docking supported
|
|
E3L062253
BDB062253
|
BDBM50594945
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCNC(=O)CCc3ccc(-c4cnc(NCc5c(F)ccc6c5CCO6)n5cnnc45)c(N)n3)cc2)C(C)(C)C)cc1
|
C54H59FN12O8S 1055.207000 |
IPOBDFFCDGTMLE-GNFFXYLRSA-N | O75530 | Polycomb protein EED |
BindingDB
BindingDB:BDBM50594945
|
Local ready
Direct docking supported
|
|
E3L062254
BDB062254
|
BDBM50594967
Cc1cc(O[C@H](C)C(=O)NCC(=O)NCC(=O)O)c2c3c(c(=O)oc2c1)CCC3
|
C20H22N2O7 402.403000 |
MCVZDCFVPSXAAF-LLVKDONJSA-N | P29375 | Lysine-specific demethylase 5A |
BindingDB, PubChem
BindingDB:BDBM50594967; PubChem:CID1796097
|
Local ready
Direct docking supported
|
|
E3L062255
BDB062255
|
BDBM50594968
CCCCCCN(C)CCn1cc(-c2cc(C(=O)O)ccn2)nn1
|
C17H25N5O2 331.420000 |
CSYJKVLAIVFBBK-UHFFFAOYSA-N | P41229 | Lysine-specific demethylase 5C |
BindingDB, PubChem
BindingDB:BDBM50594968; PubChem:CID168148191
|
Local ready
Direct docking supported
|
|
E3L062256
BDB062256
|
BDBM50595876
C[C@@H](COCCC(=O)N1CCN2c3ncc(C(F)(F)F)cc3NC(=O)C2C1)Nc1cn[nH]c(=O)c1C(F)(F)F
|
C22H23F6N7O4 563.459000 |
BAYLVRHCVANSLN-VPHXOMNUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50595876
|
Local ready
Direct docking supported
|
|
E3L062257
BDB062257
|
BDBM50595938
O=C(O)c1ccc(OCc2c(-c3c(Cl)cccc3C(F)(F)F)noc2-c2cc[nH]c2)cc1
|
C22H14ClF3N2O4 462.811000 |
NZRBQNXUTCVFCO-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50595938; PubChem:CID154649072
|
Local ready
Direct docking supported
|
|
E3L062258
BDB062258
|
BDBM50595939
O=C(O)c1ccc(SCc2c(-c3c(Cl)cccc3C(F)(F)F)noc2-c2cc[nH]c2)cc1
|
C22H14ClF3N2O3S 478.879000 |
GGFPRYDHONCEPC-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50595939; PubChem:CID168296383
|
Local ready
Direct docking supported
|
|
E3L062259
BDB062259
|
BDBM50595940
CN(Cc1c(-c2c(Cl)cccc2C(F)(F)F)noc1-c1cc[nH]c1)c1ccc(C(=O)O)cc1
|
C23H17ClF3N3O3 475.854000 |
ZOLJOOYIWDJCHA-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50595940; PubChem:CID168288607
|
Local ready
Direct docking supported
|
|
E3L062260
BDB062260
|
ROR ligand FM260
O=C(O)c1ccc(/C=C/c2c(-c3c(Cl)cccc3C(F)(F)F)noc2-c2cc[nH]c2)cc1
|
C23H14ClF3N2O3 458.823000 |
WYDKQIDQSWKBHJ-RMKNXTFCSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50595941; PubChem:CID168291240
|
Local ready
Direct docking supported
|