| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L063801
BDB063801
|
BDBM50627126
C[C@H](NC1(C)CCC1)c1cc(Cl)c2c(c1)C(=O)N(c1cccc([C@]3(c4nncn4C)C[C@H](F)C3)c1)C2
|
C28H31ClFN5O 508.041000 |
OHIWAMBAFXDJCL-HPORLSDASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM50627126
|
Local ready
Direct docking supported
|
|
E3L063802
BDB063802
|
BDBM50627127
Cn1cnnc1C(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)[C@H]1C[C@H](CC#N)C1
|
C31H33F3N6O 562.640000 |
VCIZTTBXGHPRNG-OAFSWBPASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM50627127
|
Local ready
Direct docking supported
|
|
E3L063803
BDB063803
|
BDBM50627128
C[C@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O
|
C29H32F3N5O2 539.602000 |
ITCYMXGHPXIVGP-SSOJOUAXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM50627128; PubChem:CID168262735
|
Local ready
Direct docking supported
|
|
E3L063804
BDB063804
|
BDBM50627129
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5CC6CC6C5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H32F3N5O2 551.613000 |
GPZUXZGXTOGHQQ-JAHKUGPBSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM50627129
|
Local ready
Direct docking supported
|
|
E3L063805
BDB063805
|
BDBM50627130
NC1=NCC(c2cccc(Oc3ccc(Cl)cc3)c2)C1
|
C16H15ClN2O 286.762000 |
YHXWMEXRFSXVKK-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627130; PubChem:CID172458763
|
Local ready
Direct docking supported
|
|
E3L063806
BDB063806
|
BDBM50627131
Clc1ccc(C2(C3=Cc4ccccc4C4=NCCN34)CC2)cc1
|
C20H17ClN2 320.823000 |
CZAADBAXFDHOIO-UHFFFAOYSA-N | O75530, Q66K64 | Polycomb protein EED, DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627131; PubChem:CID172450222
|
Local ready
Direct docking supported
|
|
E3L063807
BDB063807
|
BDBM50627132
COc1ccc(C2(C3=Cc4ccccc4C4=NCCN34)CC2)cc1
|
C21H20N2O 316.404000 |
RGDGHDJNAVACED-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627132; PubChem:CID172442705
|
Local ready
Direct docking supported
|
|
E3L063808
BDB063808
|
BDBM50627133
COc1ccc(C2(C3=Cc4cc(N5CCN(C)CC5)ccc4C4=NCCN34)CC2)cc1
|
C26H30N4O 414.553000 |
PAHRGUYMKQCNRV-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627133; PubChem:CID168719766
|
Local ready
Direct docking supported
|
|
E3L063809
BDB063809
|
BDBM50627134
COc1ccc(C2(c3nc(NCCN)c4ccccc4n3)CC2)cc1
|
C20H22N4O 334.423000 |
MCAOYOVDOFYSLA-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627134; PubChem:CID172459016
|
Local ready
Direct docking supported
|
|
E3L063810
BDB063810
|
DCAF1 binder 2
COc1ccc(C2(c3nc(NCCN)c4ccc(N5CCN(C)CC5)cc4n3)CC2)cc1
|
C25H32N6O 432.572000 |
XTLPTSDXAUSHCD-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627135; PubChem:CID168301061
|
Local ready
Direct docking supported
|
|
E3L063811
BDB063811
|
BDBM50627136
COc1ccc(C2(c3nc(NCCN)c4ccc(N5CCN(C(C)=O)CC5)cc4n3)CC2)cc1
|
C26H32N6O2 460.582000 |
WBQVPPQTLUULPF-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627136; PubChem:CID172458287
|
Local ready
Direct docking supported
|
|
E3L063812
BDB063812
|
BDBM50627137
CN1CCN(c2ccc3c(NCCN)nc(C4(c5ccc(Cl)cc5)CCCC4)nc3c2)CC1
|
C26H33ClN6 465.045000 |
FXEZJVHAWADIRT-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627137; PubChem:CID172471026
|
Local ready
Direct docking supported
|
|
E3L063813
BDB063813
|
BDBM50627138
CC(=O)N1CCN(c2ccc3c(NCCN)nc(C4(c5ccc(Cl)cc5)CCCC4)nc3c2)CC1
|
C27H33ClN6O 493.055000 |
QNLFBABAPIXMQM-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627138; PubChem:CID168301062
|
Local ready
Direct docking supported
|
|
E3L063814
BDB063814
|
BDBM50627139
CN1CCN(c2ccc3c(NCCN)nc(C4(c5ccc(Cl)cc5)CCCCC4)nc3c2)CC1
|
C27H35ClN6 479.072000 |
HIHIQYYMMNHQQK-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627139; PubChem:CID172461368
|
Local ready
Direct docking supported
|
|
E3L063815
BDB063815
|
BDBM50627141
CC(C)(Cc1ccccc1)C1=Cc2ccccc2C2=NCCN12
|
C21H22N2 302.421000 |
NQILQDMMFJDZNW-UHFFFAOYSA-N | O75530, Q66K64 | Polycomb protein EED, DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM50627141; PubChem:CID172445163
|
Local ready
Direct docking supported
|
|
E3L063816
BDB063816
|
BDBM50627361
O=C1NC(NC2CCCCC2)=N/C1=C\c1ccc2c(c1)OCO2
|
C17H19N3O3 313.357000 |
LRPOHOOPSDHHPW-JYRVWZFOSA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50627361; PubChem:CID172440349
|
Local ready
Direct docking supported
|
|
E3L063817
BDB063817
|
BDBM50627362
O=C1NC(NC2CCCCC2)=N/C1=C\c1ccc2ncsc2c1
|
C17H18N4OS 326.425000 |
QCHDHJOEPUQALZ-ZSOIEALJSA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50627362; PubChem:CID162346660
|
Local ready
Direct docking supported
|
|
E3L063818
BDB063818
|
BDBM50627363
O=C1NC(NC2CCCCC2)=N/C1=C\c1ccc2nnsc2c1
|
C16H17N5OS 327.413000 |
UAKPWAFLNKBBFC-JYRVWZFOSA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50627363; PubChem:CID168239448
|
Local ready
Direct docking supported
|
|
E3L063819
BDB063819
|
BDBM50627364
Cc1nc2ccc(/C=C3\N=C(NC4CCCCC4)NC3=O)cc2s1
|
C18H20N4OS 340.452000 |
QQFFZFFKGFYNKB-DHDCSXOGSA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50627364; PubChem:CID166523491
|
Local ready
Direct docking supported
|
|
E3L063820
BDB063820
|
BDBM50627365
O=C1NC(NC2CCCCC2)=N/C1=C\c1ccc2scnc2c1
|
C17H18N4OS 326.425000 |
CWWGZUUBJBDHOB-ZROIWOOFSA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50627365; PubChem:CID172465821
|
Local ready
Direct docking supported
|