| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L063761
BDB063761
|
BDBM50626762
O=C(c1ccc(Cl)cc1)C(Nc1cc(F)cc(F)c1)c1ccc(Cl)cc1F
|
C20H12Cl2F3NO 410.222000 |
LLIGNHXSLVRATC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626762; PubChem:CID172445505
|
Local ready
Direct docking supported
|
|
E3L063762
BDB063762
|
BDBM50626763
O=C(c1ccc(Cl)cc1)C(Nc1cccc(Cl)c1F)c1ccc(Cl)c(Cl)c1
|
C20H12Cl4FNO 443.132000 |
MBEDERALNDFTCL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626763; PubChem:CID172449787
|
Local ready
Direct docking supported
|
|
E3L063763
BDB063763
|
BDBM50626764
O=C(c1ccc(Cl)cc1)C(Nc1cc(F)cc(F)c1)c1ccc(Cl)c(Cl)c1
|
C20H12Cl3F2NO 426.677000 |
XGEKTCWUGQWVPD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626764; PubChem:CID172470683
|
Local ready
Direct docking supported
|
|
E3L063764
BDB063764
|
BDBM50626765
O=C(c1ccc(Cl)cc1)C(Nc1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1
|
C20H12Cl5NO 459.587000 |
GKQGCLSMOMMBFX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626765; PubChem:CID172455566
|
Local ready
Direct docking supported
|
|
E3L063765
BDB063765
|
BDBM50626766
COC(=O)/C=C/C(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C25H17Cl3FNO4 520.771000 |
QTYBOOSILQXQQT-OUKQBFOZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626766; PubChem:CID172449368
|
Local ready
Direct docking supported
|
|
E3L063766
BDB063766
|
BDBM50626767
COC(=O)CCC(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C25H19Cl3FNO4 522.787000 |
JQISSLWFXJWBAV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626767; PubChem:CID172447725
|
Local ready
Direct docking supported
|
|
E3L063767
BDB063767
|
BDBM50626768
COC(=O)CCCC(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C26H21Cl3FNO4 536.814000 |
MJXDQMPONCTWAM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626768; PubChem:CID172471355
|
Local ready
Direct docking supported
|
|
E3L063768
BDB063768
|
BDBM50626769
COC(=O)CCCCC(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C27H23Cl3FNO4 550.841000 |
LJIIXLYZLDHBJU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626769; PubChem:CID172441424
|
Local ready
Direct docking supported
|
|
E3L063769
BDB063769
|
BDBM50626770
O=C(O)/C=C/C(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C24H15Cl3FNO4 506.744000 |
ABRURZQTWWTXMD-VAWYXSNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626770; PubChem:CID172459186
|
Local ready
Direct docking supported
|
|
E3L063770
BDB063770
|
BDBM50626771
O=C(O)CCC(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C24H17Cl3FNO4 508.760000 |
JKVMZIXWFMBWRS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626771; PubChem:CID172446213
|
Local ready
Direct docking supported
|
|
E3L063771
BDB063771
|
BDBM50626772
O=C(O)CCCC(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C25H19Cl3FNO4 522.787000 |
VBRBJRJBWGGVFR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626772; PubChem:CID172448842
|
Local ready
Direct docking supported
|
|
E3L063772
BDB063772
|
BDBM50626773
O=C(O)CCCCC(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl
|
C26H21Cl3FNO4 536.814000 |
LBAAHYGGTRZFDU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626773; PubChem:CID172464113
|
Local ready
Direct docking supported
|
|
E3L063773
BDB063773
|
BDBM50626774
COc1ccc(S(=O)(=O)N(c2ccc(Cl)cc2)C(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc2Cl)cc1
|
C27H19Cl3FNO4S 578.876000 |
FKULEFQVZKNARA-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50626774; PubChem:CID172465834
|
Local ready
Direct docking supported
|
|
E3L063774
BDB063774
|
BDBM50626775
CN(C)C1CCN(C(=O)CCC(=O)N(c2ccc(Cl)cc2)C(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc2Cl)CC1
|
C31H31Cl3FN3O3 618.964000 |
AOHYGLVYDHZUJK-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626775; PubChem:CID172463496
|
Local ready
Direct docking supported
|
|
E3L063775
BDB063775
|
BDBM50626776
CCN1CCN(C(=O)CCC(=O)N(c2ccc(Cl)cc2)C(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc2Cl)CC1
|
C30H29Cl3FN3O3 604.937000 |
NCOGAYWUUOMMOT-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626776; PubChem:CID172469083
|
Local ready
Direct docking supported
|
|
E3L063776
BDB063776
|
BDBM50626777
CC(=O)N1CCN(C(=O)CCC(=O)N(c2ccc(Cl)cc2)C(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc2Cl)CC1
|
C30H27Cl3FN3O4 618.920000 |
AUGFYXYOVBERIH-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626777; PubChem:CID172463652
|
Local ready
Direct docking supported
|
|
E3L063777
BDB063777
|
BDBM50626778
O=C(c1ccc(Cl)cc1)C(c1ccc(F)cc1Cl)N(C(=O)CCC(=O)N1CCN(CCO)CC1)c1ccc(Cl)cc1
|
C30H29Cl3FN3O4 620.936000 |
ZHYYRUGADOQDEY-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626778; PubChem:CID172458124
|
Local ready
Direct docking supported
|
|
E3L063778
BDB063778
|
BDBM50626779
O=C(CCC(=O)N(c1ccc(Cl)cc1)C(C(=O)c1ccc(Cl)cc1)c1ccc(F)cc1Cl)NCCN1CCOCC1
|
C30H29Cl3FN3O4 620.936000 |
MJTVUWRKXUZRDZ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50626779; PubChem:CID172456537
|
Local ready
Direct docking supported
|
|
E3L063779
BDB063779
|
BDBM50626780
CC(C)(C)OC(=O)N1CCN(C(=O)CCC(=O)N(c2ccc(Cl)cc2)C(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc2Cl)CC1
|
C33H33Cl3FN3O5 677.000000 |
IHPSXZQBUYPFCW-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626780; PubChem:CID172439028
|
Local ready
Direct docking supported
|
|
E3L063780
BDB063780
|
Mdmx/mdm2-IN-2
O=C(c1ccc(Cl)cc1)C(c1ccc(F)cc1Cl)N(C(=O)CCC(=O)N1CCNCC1)c1ccc(Cl)cc1
|
C28H25Cl3FN3O3 576.883000 |
POLUTPKUGFNVJI-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626781; PubChem:CID168355523
|
Local ready
Direct docking supported
|