| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L065041
BDB065041
|
BDBM50646118
Cc1cc(C(=O)Nc2cccc([C@]3(C4CC4)CCNC(=O)O3)c2)nc(C2CC2)n1
|
C22H24N4O3 392.459000 |
LSHOZLJIDDUIQL-JOCHJYFZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646118; PubChem:CID177377725
|
Local ready
Direct docking supported
|
|
E3L065042
BDB065042
|
BDBM50646119
Cc1cc(C(=O)Nc2cccc([C@@]3(C4CC4)CCNC(=O)O3)c2)nc(C2CC2)n1
|
C22H24N4O3 392.459000 |
LSHOZLJIDDUIQL-QFIPXVFZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646119; PubChem:CID177377726
|
Local ready
Direct docking supported
|
|
E3L065043
BDB065043
|
Cbl-b-IN-27
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3nn(-c4cccc([C@]5(C6CC6)CCNC(=O)O5)c4)c(=O)n3c2)C1
|
C27H30F3N5O3 529.563000 |
UFYSXVVCYZMHCI-MRDQGFSESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646120; PubChem:CID172636052
|
Local ready
Direct docking supported
|
|
E3L065044
BDB065044
|
BDBM50646121
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3nn(-c4cccc([C@@]5(C6CC6)CCNC(=O)O5)c4)c(=O)n3c2)C1
|
C27H30F3N5O3 529.563000 |
UFYSXVVCYZMHCI-QLXKLKPCSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646121; PubChem:CID177377727
|
Local ready
Direct docking supported
|
|
E3L065045
BDB065045
|
BDBM50646122
O=C1NCC[C@](c2cccc(-c3cc(C(F)(F)F)c[nH]c3=O)c2)(C2CC2)O1
|
C19H17F3N2O3 378.350000 |
KEOPXKYXXMEWQZ-GOSISDBHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646122; PubChem:CID177377728
|
Local ready
Direct docking supported
|
|
E3L065046
BDB065046
|
BDBM50646123
O=C1NCC[C@@](c2cccc(-c3cc(C(F)(F)F)c[nH]c3=O)c2)(C2CC2)O1
|
C19H17F3N2O3 378.350000 |
KEOPXKYXXMEWQZ-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646123; PubChem:CID177377729
|
Local ready
Direct docking supported
|
|
E3L065047
BDB065047
|
BDBM50646353
Cc1cccc2cc(C(=O)NC3CCC(N)CC3)[nH]c12
|
C16H21N3O 271.364000 |
HUECPDIVYYQQOT-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM50646353; PubChem:CID132227631
|
Local ready
Direct docking supported
|
|
E3L065048
BDB065048
|
7-Methyl-N-phenyl-1H-indole-2-carboxamide
Cc1cccc2cc(C(=O)Nc3ccccc3)[nH]c12
|
C16H14N2O 250.301000 |
IEEMQZYPIOENMT-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM50646354; PubChem:CID166168015
|
Local ready
Direct docking supported
|
|
E3L065049
BDB065049
|
BDBM50646355
CCC(C)N[C@@H](CC[C@H](N)C(=O)O)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O
|
C19H31N7O5 437.501000 |
WFUIXHLNJVJPQY-DKCJOWAZSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM50646355; PubChem:CID177377858
|
Local ready
Direct docking supported
|
|
E3L065050
BDB065050
|
Tubulin/PARP-IN-2
O=c1cc(-c2ccc(F)cc2)oc2cc(-c3ccoc3)ccc12
|
C19H11FO3 306.292000 |
HSICEIFWMLSUPK-UHFFFAOYSA-N | P09874 | Poly [ADP-ribose] polymerase 1 |
BindingDB, PubChem
BindingDB:BDBM50646371; PubChem:CID169494241
|
Local ready
Direct docking supported
|
|
E3L065051
BDB065051
|
BDBM50646500
CC(C)c1ccccc1-c1ncc2ccc(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C(C)C)cc3)c2n1
|
C30H28F3N5O 531.582000 |
VGAZPJKGOOKEAC-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646500; PubChem:CID175999195
|
Local ready
Direct docking supported
|
|
E3L065052
BDB065052
|
BDBM50646501
COc1ccccc1-c1ncc2ccc(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C(C)C)cc3)c2n1
|
C28H24F3N5O2 519.527000 |
RNGZMNNDDVNYJZ-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646501; PubChem:CID177377969
|
Local ready
Direct docking supported
|
|
E3L065053
BDB065053
|
BDBM50646502
CC(C)n1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)ccc3cnc(-c4ccccc4OC(F)(F)F)nc32)cc1
|
C28H21F6N5O2 573.497000 |
QVMLBEDORILBMR-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646502; PubChem:CID177377970
|
Local ready
Direct docking supported
|
|
E3L065054
BDB065054
|
BDBM50646503
Cc1ccccc1-c1ncc2ccc(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C(C)C)cc3)c2n1
|
C28H24F3N5O 503.528000 |
NUFGEWLSWVHTLI-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646503; PubChem:CID177377971
|
Local ready
Direct docking supported
|
|
E3L065055
BDB065055
|
BDBM50646504
CC(C)n1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)ccc3cnc(-c4ccccc4C(F)(F)F)nc32)cc1
|
C28H21F6N5O 557.498000 |
QQNWJEKULQKUQP-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646504; PubChem:CID177377972
|
Local ready
Direct docking supported
|
|
E3L065056
BDB065056
|
BDBM50646505
CC(C)n1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)ccc3cnc(-c4ccccc4F)nc32)cc1
|
C27H21F4N5O 507.491000 |
PDXPUIPJFARYOQ-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646505; PubChem:CID177377973
|
Local ready
Direct docking supported
|
|
E3L065057
BDB065057
|
BDBM50646506
CC(C)n1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)ccc3cnc(-c4ccccc4Cl)nc32)cc1
|
C27H21ClF3N5O 523.946000 |
RHJQUHYQQPCYCZ-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646506; PubChem:CID177377974
|
Local ready
Direct docking supported
|
|
E3L065058
BDB065058
|
BDBM50646507
CC(C)n1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)ccc3cnc(-c4c(F)cccc4Cl)nc32)cc1
|
C27H20ClF4N5O 541.936000 |
LLSHXMXIFDLOLI-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646507; PubChem:CID177377975
|
Local ready
Direct docking supported
|
|
E3L065059
BDB065059
|
BDBM50646508
CC(C)n1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)ccc3cnc(-c4c(Cl)cccc4Cl)nc32)cc1
|
C27H20Cl2F3N5O 558.391000 |
JGUQTQJAOHIDBT-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646508; PubChem:CID177377976
|
Local ready
Direct docking supported
|
|
E3L065060
BDB065060
|
BDBM50646509
COc1cccc(F)c1-c1ncc2ccc(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C(C)C)cc3)c2n1
|
C28H23F4N5O2 537.517000 |
CKWBMDPUPBWUGR-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50646509; PubChem:CID177377977
|
Local ready
Direct docking supported
|