| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L065021
BDB065021
|
BDBM50645685
C#CCCCNC(=O)c1ccc(-n2cnc(NC(=O)[C@H]3CCN(C#N)C3)c2)cc1
|
C21H22N6O2 390.447000 |
LSHAYFDZIOIKII-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM50645685; PubChem:CID168355575
|
Local ready
Direct docking supported
|
|
E3L065022
BDB065022
|
BDBM50645686
Cc1nn(C)c2cc(-c3ccc(-n4cnc(NC(=O)[C@H]5CCN(C#N)C5)c4)cc3)ccc12
|
C24H23N7O 425.496000 |
MEYYPLAULVPYIK-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM50645686; PubChem:CID177377446
|
Local ready
Direct docking supported
|
|
E3L065023
BDB065023
|
BDBM50646099
CN1Cc2cc3c(cc2C1)C(=O)N(C1CCC(=O)NC1=O)C3
|
C16H17N3O3 299.330000 |
PRTGVDSIUYJKFP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM50646099; PubChem:CID170390722
|
Local ready
Direct docking supported
|
|
E3L065024
BDB065024
|
BDBM50646101
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3nn(-c4cccc([C@]5(c6nncn6C)C[C@@H](C)C5)c4)c(=O)n3c2)C1
|
C28H32F3N7O 539.606000 |
MIDJBXBDZRDWNR-RWYJCYHVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50646101
|
Local ready
Direct docking supported
|
|
E3L065025
BDB065025
|
BDBM50646102
Cn1cnnc1[C@]1(c2cccc(-n3nc4c(C(F)(F)F)cccn4c3=O)c2)C[C@H](C)C1
|
C21H19F3N6O 428.418000 |
FNXVMILWZUOFQU-NXHRWCDGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50646102
|
Local ready
Direct docking supported
|
|
E3L065026
BDB065026
|
BDBM50646103
CC1CC(c2cccc(-n3nc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cn4c3=O)c2)(n2cccn2)C1
|
C28H31F3N6O 524.591000 |
UEJHKAMQNRQSOJ-DIQZNMANSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646103; PubChem:CID177377712
|
Local ready
Direct docking supported
|
|
E3L065027
BDB065027
|
BDBM50646104
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3nn(-c4cccc([C@]5(C(=O)N(C)C)C[C@@H](C)C5)c4)c(=O)n3c2)C1
|
C28H34F3N5O2 529.607000 |
XMTBDAFJNXLGDP-RWYJCYHVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50646104
|
Local ready
Direct docking supported
|
|
E3L065028
BDB065028
|
BDBM50646105
CNC(=O)[C@]1(c2cccc(-n3nc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cn4c3=O)c2)C[C@H](C)C1
|
C27H32F3N5O2 515.580000 |
YRMLHYLVPLNXCV-QSAFDGGLSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50646105
|
Local ready
Direct docking supported
|
|
E3L065029
BDB065029
|
BDBM50646106
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3nn(-c4cccc(C5(C)CC(=O)NC(=O)C5)c4)c(=O)n3c2)C1
|
C26H28F3N5O3 515.536000 |
PJMGLEDIZLGUTG-INIZCTEOSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646106; PubChem:CID177377715
|
Local ready
Direct docking supported
|
|
E3L065030
BDB065030
|
BDBM50646107
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3nn(-c4cccc([C@]5(C)CCNC(=O)C5)c4)c(=O)n3c2)C1
|
C26H30F3N5O2 501.553000 |
RNNGOKAOZYGEFA-SSOJOUAXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646107; PubChem:CID171902331
|
Local ready
Direct docking supported
|
|
E3L065031
BDB065031
|
BDBM50646108
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3nn(-c4cccc([C@@]5(C)CCNC(=O)C5)c4)c(=O)n3c2)C1
|
C26H30F3N5O2 501.553000 |
RNNGOKAOZYGEFA-GKVSMKOHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646108; PubChem:CID177377716
|
Local ready
Direct docking supported
|
|
E3L065032
BDB065032
|
BDBM50646109
Cc1cc(C(=O)Nc2cccc([C@]3(C)CCNC(=O)C3)c2)nc(C2CC2)n1
|
C21H24N4O2 364.449000 |
MJHAVQLUTIGEJB-OAQYLSRUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646109; PubChem:CID177377717
|
Local ready
Direct docking supported
|
|
E3L065033
BDB065033
|
BDBM50646110
Cc1cc(C(=O)Nc2cccc([C@@]3(C)CCNC(=O)C3)c2)nc(C2CC2)n1
|
C21H24N4O2 364.449000 |
MJHAVQLUTIGEJB-NRFANRHFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646110; PubChem:CID177377718
|
Local ready
Direct docking supported
|
|
E3L065034
BDB065034
|
BDBM50646111
Cc1cc(C(=O)Nc2cccc([C@]3(C)CCNC(=O)O3)c2)nc(C2CC2)n1
|
C20H22N4O3 366.421000 |
GEVKVDLYMGMTDW-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646111; PubChem:CID171902332
|
Local ready
Direct docking supported
|
|
E3L065035
BDB065035
|
BDBM50646112
Cc1cc(C(=O)Nc2cccc([C@@]3(C)CCNC(=O)O3)c2)nc(C2CC2)n1
|
C20H22N4O3 366.421000 |
GEVKVDLYMGMTDW-HXUWFJFHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646112; PubChem:CID177377719
|
Local ready
Direct docking supported
|
|
E3L065036
BDB065036
|
BDBM50646113
Cc1cc(C(=O)Nc2cccc(C3(C)CNC(=O)O3)c2)nc(C2CC2)n1
|
C19H20N4O3 352.394000 |
GNDVMQABSPDLHM-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646113; PubChem:CID177377720
|
Local ready
Direct docking supported
|
|
E3L065037
BDB065037
|
BDBM50646114
Cc1cc(C(=O)Nc2cccc(C3(C)CCNC(=O)N3)c2)nc(C2CC2)n1
|
C20H23N5O2 365.437000 |
RSEGYDPUVGSPSI-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646114; PubChem:CID177377721
|
Local ready
Direct docking supported
|
|
E3L065038
BDB065038
|
BDBM50646115
Cc1cc(C(=O)Nc2cccc(C3(C)CCNC(=O)N3C)c2)nc(C2CC2)n1
|
C21H25N5O2 379.464000 |
RDBOXUQBSWYKLE-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646115; PubChem:CID177377722
|
Local ready
Direct docking supported
|
|
E3L065039
BDB065039
|
BDBM50646116
CC[C@@]1(c2cccc(NC(=O)c3cc(C)nc(C4CC4)n3)c2)CCNC(=O)O1
|
C21H24N4O3 380.448000 |
PVCBVOSRDBMIPM-NRFANRHFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646116; PubChem:CID177377723
|
Local ready
Direct docking supported
|
|
E3L065040
BDB065040
|
BDBM50646117
CC[C@]1(c2cccc(NC(=O)c3cc(C)nc(C4CC4)n3)c2)CCNC(=O)O1
|
C21H24N4O3 380.448000 |
PVCBVOSRDBMIPM-OAQYLSRUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50646117; PubChem:CID177377724
|
Local ready
Direct docking supported
|