| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L065577
LIG000147
|
10
O=C1CCC(N2C(=O)c3ccc(CNC(=O)Nc4ccccc4Cl)cc3C2=O)C(=O)N1
|
C21H17ClN4O5 440.843000 |
BTMAGCJFZAIFOH-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1000
|
Local ready
Direct docking supported
|
|
E3L065578
LIG000148
|
46
CC(C)(C)OC(=O)N1CCN(c2cc3c(cc2F)C(=O)N(C2CCC(=O)NC2=O)C3=O)CC1
|
C22H25FN4O6 460.462000 |
BTQQJBNIFLRMDS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB110
|
Local ready
Direct docking supported
|
|
E3L065579
LIG000149
|
ZXH-2-138
O=C1CCC(N2Cc3c(NC4=NC(c5ccc(-c6ccccc6)cc5)Nc5[nH]cnc54)cccc3C2=O)C(=O)N1
|
C30H25N7O3 531.576000 |
BTRMMFYJMZLSTF-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1148
|
Local ready
Direct docking supported
|
|
E3L065580
LIG000150
|
79
O=C1CCC(N2Cc3cc(NC(=O)C4=Cc5ccc(C(F)(F)F)cc5OC4)ccc3C2=O)C(=O)N1
|
C24H18F3N3O5 485.418000 |
BTYAHFGEMWWMRT-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1205
|
Local ready
Direct docking supported
|
|
E3L065581
LIG000151
|
LIG000151
CNC(=O)C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](c1cc(C)no1)C(C)C)c1ccc(-c2scnc2C)cc1
|
C28H35N5O5S 553.685000 |
BUFJKORGWVCZBG-HXKBJWFLSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, e3_ligand
BindingDB:BDBM50615679; e3_ligand:24
|
Local ready
Direct docking supported
|
|
E3L065582
LIG000152
|
61
O=C1CCC(N2Cc3cc(NC(=O)c4ccc5ncsc5c4)ccc3C2=O)C(=O)N1
|
C21H16N4O4S 420.450000 |
BUKXXJVKMXZXHH-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1196
|
Local ready
Direct docking supported
|
|
E3L065583
LIG000153
|
LL-K12-17
CCn1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(N3CCN(C(=O)[C@H](C)NC(C)=O)CC3)nc21
|
C24H28Cl2N10O2 559.462000 |
BULCSZAPIUXBHD-ZDUSSCGKSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB466
|
Local ready
Direct docking supported
|
|
E3L065584
LIG000154
|
MGD-15
Cc1ccc(CNc2cccc3c2CN(C)N(C2CCC(=O)NC2=O)C3=O)cc1
|
C22H24N4O3 392.459000 |
BUNLELBHVDUDPW-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB322
|
Local ready
Direct docking supported
|
|
E3L065585
LIG000155
|
11c
Cc1cc(N)ccc1C(=O)NC1CCC(=O)NC1=O
|
C13H15N3O3 261.281000 |
BUTHFOQUICVORE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630598; MolGlueDB:MGDB305
|
Local ready
Direct docking supported
|
|
E3L065586
LIG000156
|
EST1089
COc1ccc(C(=O)/C=C/C(=O)N2CCN(c3ccc(Nc4ncc5c(C)c(C(C)=O)c(=O)n(C6CCCC6)c5n4)nc3)CC2)cc1
|
C35H37N7O5 635.725000 |
BVBLSFMBNBIVMI-FYWRMAATSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB657
|
Local ready
Direct docking supported
|
|
E3L065587
LIG000157
|
LIG000157
CC[C@H](C)C(N)C(=O)N[C@H]1CC(=O)NC1=O
|
C10H17N3O3 227.264000 |
BVZSZYYFCDLUEQ-AJFZSALYSA-N | Q96SW2 | - |
e3_ligand
e3_ligand:117
|
Local ready
Direct docking supported
|
|
E3L065588
LIG000158
|
45
COc1cc2ccc(C(=O)Nc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc2cn1
|
C24H20N4O5 444.447000 |
BWEJJXAXDRVATO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB750
|
Local ready
Direct docking supported
|
|
E3L065589
LIG000159
|
EM12-SO2Tr1
O=C1CCC(N2Cc3ccc(S(=O)(=O)n4nccn4)cc3C2=O)C(=O)N1
|
C15H13N5O5S 375.366000 |
BWKROUZQCPJHCS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630769; MolGlueDB:MGDB1255
|
Local ready
Direct docking supported
|
|
E3L065590
LIG000160
|
20
CCCCNc1ccc2c(=O)n(C3CCC(=O)NC3=O)nnc2c1
|
C16H19N5O3 329.360000 |
BWYRJHMYILLTOI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630606; MolGlueDB:MGDB449
|
Local ready
Direct docking supported
|
|
E3L065591
LIG000161
|
8
O=C1CCC(N2Cc3cc(-c4cc(CN5CCCC5)c5[nH]nc(C6CC6)c5n4)ccc3C2=O)C(=O)N1
|
C27H28N6O3 484.560000 |
BXYIZAXLXHKKNJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1499
|
Local ready
Direct docking supported
|
|
E3L065592
LIG000162
|
8e
Nc1ccccc1C(=O)NC1CCC(=O)NC1=O
|
C12H13N3O3 247.254000 |
BXYYCADYTWTGMG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630594; MolGlueDB:MGDB821
|
Local ready
Direct docking supported
|
|
E3L065593
LIG000163
|
7d
COc1cc2onc(C)c2cc1NS(=O)(=O)c1cc(Br)ccc1OCC(=O)NCCCCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C35H35BrN6O10S 811.668000 |
BYMCDZYPLRVPJY-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB729
|
Local ready
Direct docking supported
|
|
E3L065594
LIG000164
|
LL-K12-15
CCn1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(N3CCN(Cc4ccncc4)CC3)nc21
|
C25H26Cl2N10 537.459000 |
BYVSCKPDCFRSML-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB474
|
Local ready
Direct docking supported
|
|
E3L065595
LIG000165
|
LYG-409
O=C1CCC(N2Cc3cc(CNC(=O)C4=Cc5cc(OC(F)(F)F)ccc5OC4)ccc3C2=O)C(=O)N1
|
C25H20F3N3O6 515.444000 |
BYWKZOLIKCQOGA-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1352
|
Local ready
Direct docking supported
|
|
E3L065596
LIG000166
|
6F
Cc1c(C#CCNC(=O)OC(C)(C)C)cccc1N1CCC(=O)NC1=O
|
C19H23N3O4 357.410000 |
BYYNQPPTKWNBOG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB234
|
Local ready
Direct docking supported
|