| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007041
BDB007041
|
BDBM156204
CC[C@@H]1COCCN1C[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ncc(C(F)(F)CC)cc21
|
C26H41F2N5O2 493.643000 |
AQXBHZMJBDZCFT-HMXCVIKNSA-N | Q13490 | Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM156204; PubChem:CID90232131
|
Local ready
Direct docking supported
|
|
E3L007042
BDB007042
|
BDBM156205
CCC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCOC[C@H]1COC)CC2(C)C
|
C26H41F2N5O3 509.642000 |
GBGYKSSIYCEMCL-HMXCVIKNSA-N | P98170, Q13490 | Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP |
BindingDB
BindingDB:BDBM156205
|
Local ready
Direct docking supported
|
|
E3L007043
BDB007043
|
BDBM156206
COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(Cc3ccccc3)nc21
|
C25H34N4O2 422.573000 |
XFAYZDLDIOLAFU-WIYYLYMNSA-N | P98170, Q13490 | E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM156206; PubChem:CID71003218
|
Local ready
Direct docking supported
|
|
E3L007044
BDB007044
|
BDBM156212
C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)CCN1
|
C23H29FN4O 396.510000 |
QRILDYVZZITLEI-MRXNPFEDSA-N | P98170, Q13490 | E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM156212; PubChem:CID71003497
|
Local ready
Direct docking supported
|
|
E3L007045
BDB007045
|
Cambridge id 7011428
COc1ccc(C(Nc2cc(C)ccn2)c2ccc3cccnc3c2O)cc1O
|
C23H21N3O3 387.439000 |
FCTHDIWMHUZDNV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156414; PubChem:CID2923415
|
Local ready
Direct docking supported
|
|
E3L007046
BDB007046
|
BDBM156415
Cc1cccc(NC(c2ccc(OC(F)(F)F)cc2)c2ccc3cccnc3c2O)n1
|
C23H18F3N3O2 425.410000 |
OGZDISPFPXWYMT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156415; PubChem:CID67987468
|
Local ready
Direct docking supported
|
|
E3L007047
BDB007047
|
BDBM156416
Cc1cccc(NC(c2cccc(C(F)(F)F)c2)c2ccc3cccnc3c2O)n1
|
C23H18F3N3O 409.411000 |
FYPUIPYMWVYSSE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156416; PubChem:CID54673784
|
Local ready
Direct docking supported
|
|
E3L007048
BDB007048
|
BDBM156418
Cc1cccc(NC(c2cccc(Cl)c2Cl)c2ccc3cccnc3c2O)n1
|
C22H17Cl2N3O 410.304000 |
QSZFNQFVVDPJNS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156418; PubChem:CID58542818
|
Local ready
Direct docking supported
|
|
E3L007049
BDB007049
|
BDBM156419
Cc1ccnc(NC(c2cccc(Cl)c2Cl)c2ccc3cccnc3c2O)c1
|
C22H17Cl2N3O 410.304000 |
HQICAVDTVBACIN-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM156419; PubChem:CID2907163
|
Local ready
Direct docking supported
|
|
E3L007050
BDB007050
|
BDBM156420
Cc1ccnc(NC(c2ccccc2Cl)c2ccc3cccnc3c2O)c1
|
C22H18ClN3O 375.859000 |
BKOLRAXMMXDABH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156420; PubChem:CID15998359
|
Local ready
Direct docking supported
|
|
E3L007051
BDB007051
|
BDBM156422
COc1ccc(C(Nc2cccc(C)n2)c2ccc3cccnc3c2O)cc1O
|
C23H21N3O3 387.439000 |
GBVYRUWUOYSPSL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156422; PubChem:CID53307498
|
Local ready
Direct docking supported
|
|
E3L007052
BDB007052
|
BDBM156423
Oc1c(C(Nc2ccccn2)c2cc(Cl)ccc2Cl)ccc2cccnc12
|
C21H15Cl2N3O 396.277000 |
HIQGIODAOSUAIJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156423; PubChem:CID53307499
|
Local ready
Direct docking supported
|
|
E3L007053
BDB007053
|
BDBM156430
Cc1cccc(NC(c2ccc3cccnc3c2O)c2c(F)c(F)cc(F)c2F)n1
|
C22H15F4N3O 413.374000 |
YDCZODYBERKOLC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156430; PubChem:CID58542811
|
Local ready
Direct docking supported
|
|
E3L007054
BDB007054
|
BDBM156478
Oc1c(C(Nc2ccc(Cl)cn2)c2ccc(C(F)(F)F)cc2)ccc2cccnc12
|
C22H15ClF3N3O 429.829000 |
QUZWUSZETMJLKQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156478; PubChem:CID67987447
|
Local ready
Direct docking supported
|
|
E3L007055
BDB007055
|
BDBM156479
Oc1c(C(Nc2ccc(Cl)cn2)c2ccc(Cl)c(Cl)c2)ccc2cccnc12
|
C21H14Cl3N3O 430.722000 |
VFGQAVMHLLILFS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156479; PubChem:CID58543186
|
Local ready
Direct docking supported
|
|
E3L007056
BDB007056
|
BDBM156483
Cc1cc(Cl)cnc1NC(c1cc(C(F)(F)F)ccc1Cl)c1ccc2cccnc2c1O
|
C23H16Cl2F3N3O 478.301000 |
RCGJZGRXRZVCHV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156483; PubChem:CID67987469
|
Local ready
Direct docking supported
|
|
E3L007057
BDB007057
|
BDBM156487
Oc1c(C(Nc2ccc(C(F)(F)F)nc2)c2cc(C(F)(F)F)ccc2Cl)ccc2cccnc12
|
C23H14ClF6N3O 497.826000 |
MHXDFMCFQCOGME-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156487; PubChem:CID88542921
|
Local ready
Direct docking supported
|
|
E3L007058
BDB007058
|
BDBM156492
Oc1c(C(Nc2ccc(Cl)cn2)c2ccc(Cl)c(C(F)(F)F)c2)ccc2cccnc12
|
C22H14Cl2F3N3O 464.274000 |
SMNLKPREGGTNNA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156492; PubChem:CID58543184
|
Local ready
Direct docking supported
|
|
E3L007059
BDB007059
|
BDBM156495
Oc1c(C(Nc2ccc(F)cn2)c2c(F)c(F)cc(F)c2F)ccc2cccnc12
|
C21H12F5N3O 417.337000 |
LFKSHSSIYOGROD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156495; PubChem:CID58542892
|
Local ready
Direct docking supported
|
|
E3L007060
BDB007060
|
BDBM156506
Cc1cccc(NC(c2ccc(Cl)c(Cl)c2)c2ccc3ccc(C)nc3c2O)n1
|
C23H19Cl2N3O 424.331000 |
RDXYXFSMJLWUDK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156506; PubChem:CID58542735
|
Local ready
Direct docking supported
|