| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007061
BDB007061
|
BDBM156517
Cc1cccc(NC(c2ccc3ccc(C)nc3c2O)c2c(Cl)cccc2Cl)n1
|
C23H19Cl2N3O 424.331000 |
QLDMGYSSFOUUNR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156517; PubChem:CID58542963
|
Local ready
Direct docking supported
|
|
E3L007062
BDB007062
|
BDBM156527
Oc1c(C(Nc2ccc(F)cn2)c2ccc(F)cc2Cl)ccc2cccnc12
|
C21H14ClF2N3O 397.812000 |
WAXACFSQQUNXME-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156527; PubChem:CID58542727
|
Local ready
Direct docking supported
|
|
E3L007063
BDB007063
|
BDBM156528
Cc1ccc2ccc(C(Nc3cccnc3)c3c(F)c(F)c(OCC(F)(F)F)c(F)c3F)c(O)c2n1
|
C24H16F7N3O2 511.397000 |
DTLSGZWDANMNFV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156528; PubChem:CID88542939
|
Local ready
Direct docking supported
|
|
E3L007064
BDB007064
|
BDBM156540
Oc1c(C(Nc2ccc(F)cn2)c2ccc(Cl)c(Cl)c2)ccc2cccnc12
|
C21H14Cl2FN3O 414.267000 |
XVOHRENASVMKSR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156540; PubChem:CID58542865
|
Local ready
Direct docking supported
|
|
E3L007065
BDB007065
|
BDBM156543
Cc1cc(NC(c2ccccc2Cl)c2ccc3cccnc3c2O)ncc1F
|
C22H17ClFN3O 393.849000 |
GUYSNDUVUVJUKP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156543; PubChem:CID58543085
|
Local ready
Direct docking supported
|
|
E3L007066
BDB007066
|
BDBM156545
Cc1cc(NC(c2cc(Cl)ccc2Cl)c2ccc3cccnc3c2O)ncc1F
|
C22H16Cl2FN3O 428.294000 |
CFWLIDOHUBPDBN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156545; PubChem:CID58542740
|
Local ready
Direct docking supported
|
|
E3L007067
BDB007067
|
BDBM156617
COc1ccc(C(Nc2ncc(Cl)cc2C)c2ccc3cccnc3c2O)cc1OC
|
C24H22ClN3O3 435.911000 |
MVUOHRYXDQYLSF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156617; PubChem:CID67987496
|
Local ready
Direct docking supported
|
|
E3L007068
BDB007068
|
BDBM156618
COc1ccc(C(Nc2cc(C)c(Cl)cn2)c2ccc3cccnc3c2O)cc1OC
|
C24H22ClN3O3 435.911000 |
NPDAPYIBNMGBAK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156618; PubChem:CID67987490
|
Local ready
Direct docking supported
|
|
E3L007069
BDB007069
|
BDBM156619
COc1ccc(C(Nc2cc(Cl)c(Cl)cn2)c2ccc3cccnc3c2O)cc1OC
|
C23H19Cl2N3O3 456.329000 |
VPXBDNVUYCFBMU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156619; PubChem:CID67987489
|
Local ready
Direct docking supported
|
|
E3L007070
BDB007070
|
BDBM156620
COc1ccc(C(Nc2cc(C)c(Cl)cn2)c2ccc3cccnc3c2O)c(OC)c1OC
|
C25H24ClN3O4 465.937000 |
XBEHCOBNEHDJGX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156620; PubChem:CID67987461
|
Local ready
Direct docking supported
|
|
E3L007071
BDB007071
|
BDBM156621
COc1ccc(C(Nc2cc(Cl)c(Cl)cn2)c2ccc3cccnc3c2O)c(OC)c1OC
|
C24H21Cl2N3O4 486.355000 |
UPCSPJGTUWHCAE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156621; PubChem:CID67987486
|
Local ready
Direct docking supported
|
|
E3L007072
BDB007072
|
BDBM156626
Cc1nc(NC(c2ccc(Cl)c(Cl)c2)c2ccc3cccnc3c2O)c(Cl)cc1Cl
|
C22H15Cl4N3O 479.194000 |
HZGVFSASJNRQAV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156626; PubChem:CID58543088
|
Local ready
Direct docking supported
|
|
E3L007073
BDB007073
|
BDBM156632
COc1ccc(C(Nc2ncc(Cl)cc2C)c2ccc3cccnc3c2O)c(OC)c1OC
|
C25H24ClN3O4 465.937000 |
CMWKCNRKEDLALP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156632; PubChem:CID67987467
|
Local ready
Direct docking supported
|
|
E3L007074
BDB007074
|
BDBM156635
COc1ccc(C(Nc2nc(C)c(Cl)cc2Cl)c2ccc3cccnc3c2O)c(OC)c1OC
|
C25H23Cl2N3O4 500.382000 |
OYGCVJIFXAIWEU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156635; PubChem:CID67987495
|
Local ready
Direct docking supported
|
|
E3L007075
BDB007075
|
BDBM156639
COc1cc(Cl)cnc1NC(c1ccc(OC)c(OC)c1OC)c1ccc2cccnc2c1O
|
C25H24ClN3O5 481.936000 |
SEBJYFDXYMHRMP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156639; PubChem:CID67987492
|
Local ready
Direct docking supported
|
|
E3L007076
BDB007076
|
BDBM156644
CCc1c(Cl)cnc(NC(c2ccc(OC)c(OC)c2OC)c2ccc3cccnc3c2O)c1F
|
C26H25ClFN3O4 497.954000 |
SLKFGGXLYSGJIS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156644; PubChem:CID67987498
|
Local ready
Direct docking supported
|
|
E3L007077
BDB007077
|
BDBM156654
Oc1c(C(Nc2ccccn2)c2ccc(Cl)cc2Cl)ccc2cccnc12
|
C21H15Cl2N3O 396.277000 |
ZQNSVWDKNCLXET-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156654; PubChem:CID2895914
|
Local ready
Direct docking supported
|
|
E3L007078
BDB007078
|
BDBM156655
Oc1c(C(Nc2cccnc2)c2cccs2)ccc2cccnc12
|
C19H15N3OS 333.416000 |
YXIFQESPJHWOSI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156655; PubChem:CID2977733
|
Local ready
Direct docking supported
|
|
E3L007079
BDB007079
|
BDBM156660
Cc1ccnc(NC(c2ccc3cccnc3c2O)c2sccc2C)c1
|
C21H19N3OS 361.470000 |
HMRFJTICBMUXDH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM156660; PubChem:CID2895553
|
Local ready
Direct docking supported
|
|
E3L007080
BDB007080
|
Entrectinib
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1
|
C31H34F2N6O2 560.649000 |
HAYYBYPASCDWEQ-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM158154; PubChem:CID25141092
|
Local ready
Direct docking supported
|