| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L008081
BDB008081
|
BDBM192235
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(N[C@H](CC(C)C)C(=O)NCCO)C(=O)NCc1ccccc1
|
C28H35ClN4O5 543.064000 |
YSLXSHNOVDKRBA-LETIRJCYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192235; PubChem:CID56941382
|
Local ready
Direct docking supported
|
|
E3L008082
BDB008082
|
BDBM192236
CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12)C(=O)NCCO
|
C26H31ClN4O5 515.010000 |
HQYGMJJJRLYSAC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192236; PubChem:CID56941530
|
Local ready
Direct docking supported
|
|
E3L008083
BDB008083
|
BDBM192237
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(N[C@H](CC(C)C)C(=O)NCCCN1CCOCC1)C(=O)NCc1ccccc1
|
C33H44ClN5O5 626.198000 |
YGHPSLPKTNEEMH-SCBLGKRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192237; PubChem:CID56941383
|
Local ready
Direct docking supported
|
|
E3L008084
BDB008084
|
BDBM192238
CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12)C(=O)NCCCN1CCOCC1
|
C31H40ClN5O5 598.144000 |
BXMBQDSQLPJRKK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192238; PubChem:CID56941531
|
Local ready
Direct docking supported
|
|
E3L008085
BDB008085
|
BDBM192239
CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)NO)[nH]c2cc(Cl)ccc12)C(=O)NO
|
C24H28ClN5O5 501.971000 |
VRQFWSWBTGHUMK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192239; PubChem:CID56941384
|
Local ready
Direct docking supported
|
|
E3L008086
BDB008086
|
BDBM192240
CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12)C(=O)NCCN1CCOCC1
|
C30H38ClN5O5 584.117000 |
CZXLKXIBENLKBB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192240; PubChem:CID56941532
|
Local ready
Direct docking supported
|
|
E3L008087
BDB008087
|
BDBM192241
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccccc1
|
C25H28ClN3O4 469.969000 |
LQMQDLYPMZBDEL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192241; PubChem:CID121596252
|
Local ready
Direct docking supported
|
|
E3L008088
BDB008088
|
BDBM192242
CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NCc1ccccc1)C(=O)NC1CCCCC1
|
C26H30ClN3O3 467.997000 |
RLBMFFMCMZEVKG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192242; PubChem:CID56942533
|
Local ready
Direct docking supported
|
|
E3L008089
BDB008089
|
BDBM192243
O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCc1ccccc1)C(=O)NC1CCCCC1
|
C24H26ClN3O3 439.943000 |
XDUGSDDMLYOUOG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192243; PubChem:CID56942534
|
Local ready
Direct docking supported
|
|
E3L008090
BDB008090
|
BDBM192244
CC(C)(C)NC(=O)C(NCc1ccc(Cl)cc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
|
C22H23Cl2N3O3 448.350000 |
DDXQPBIVXUVPLH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192244; PubChem:CID56941080
|
Local ready
Direct docking supported
|
|
E3L008091
BDB008091
|
BDBM192245
CC(=O)N(Cc1ccccc1)C(C(=O)NC1CCCCC1)c1c(C(=O)NCCc2ccncc2)[nH]c2cc(Cl)ccc12
|
C33H36ClN5O3 586.136000 |
NUDOFPZNMCFUGO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192245; PubChem:CID56941081
|
Local ready
Direct docking supported
|
|
E3L008092
BDB008092
|
BDBM192246
COCCNC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC1CCCCC1)N(Cc1ccccc1)C(C)=O
|
C29H35ClN4O4 539.076000 |
AVSQQXFFLKCQAA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM192246; PubChem:CID56941236
|
Local ready
Direct docking supported
|
|
E3L008093
BDB008093
|
BDBM193080
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC(N4CCN(c5ccc(NC6CCC(=O)NC6=O)cc5F)CC4)CC3)nc2)N1CC(F)F
|
C38H44F3N9O2 715.825000 |
VKXBICAYRASHLV-SDYXXRSESA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM193080
|
Local ready
Direct docking supported
|
|
E3L008094
BDB008094
|
BDBM193082
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC(N4CCN(c5ccc(NC6CCC(=O)NC6=O)cc5F)CC4)CC3)nc2)N1CC(C)(C)F
|
C40H49F2N9O2 725.889000 |
ZTWCGKQCSGYWQV-COGRHDQJSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM193082
|
Local ready
Direct docking supported
|
|
E3L008095
BDB008095
|
BDBM193083
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC(N4CCC(c5ccc(NC6CCC(=O)NC6=O)cc5F)CC4)CC3)nc2)N1CC(F)F
|
C39H45F3N8O2 714.837000 |
MHLAGDGKSQVFQO-UXLHZAISSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM193083
|
Local ready
Direct docking supported
|
|
E3L008096
BDB008096
|
BDBM193084
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3C[C@@H]4[C@@H](CN5CCN6c7cc8c(cc7OC[C@@H]6C5)C(=O)N(C5CCC(=O)NC5=O)C8)[C@@H]4C3)nc2)N1CC(F)F
|
C42H45F2N9O4 777.877000 |
XWLHEKLYOZIHSW-BDYXAUMISA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM193084
|
Local ready
Direct docking supported
|
|
E3L008097
BDB008097
|
BDBM193085
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)nc2)N1CC(F)F
|
C42H47F2N9O4 779.893000 |
HIPYCPSIFQICFX-ZELNDKNYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM193085
|
Local ready
Direct docking supported
|
|
E3L008098
BDB008098
|
BDBM195608
CC(C)c1c(-c2ccccc2)[nH]c2c(C#N)cnn2c1=O
|
C16H14N4O 278.315000 |
DHXKRMSKXLDZGY-UHFFFAOYSA-N | P29375, P41229, Q8NHM5, Q9BY66 | Lysine-specific demethylase 5C, Lysine-specific demethylase 2B, Lysine-specific demethylase 5A, Lysine-specific demethylase 5D |
BindingDB
BindingDB:BDBM195608
|
Local ready
Direct docking supported
|
|
E3L008099
BDB008099
|
BDBM195609
CCc1c(-c2ccccc2C)[nH]c2c(C#N)cnn2c1=O
|
C16H14N4O 278.315000 |
OXELDRCVUWWSFZ-UHFFFAOYSA-N | P29375, P41229, Q8NHM5 | Lysine-specific demethylase 5A, Lysine-specific demethylase 5C, Lysine-specific demethylase 2B |
BindingDB
BindingDB:BDBM195609
|
Local ready
Direct docking supported
|
|
E3L008100
BDB008100
|
BDBM195610
CCc1c(C)[nH]c2c(C#N)cnn2c1=O
|
C10H10N4O 202.217000 |
AEGZTINJBDVGEP-UHFFFAOYSA-N | P29375 | Lysine-specific demethylase 5A |
BindingDB
BindingDB:BDBM195610
|
Local ready
Direct docking supported
|