| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010521
BDB010521
|
BDBM224086
C[C@@](CO)(Nc1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)c1ccccc1
|
C30H32ClN7O3 574.085000 |
SVMLACNQIJTXAA-SZUZZLPFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224086
|
Local ready
Direct docking supported
|
|
E3L010522
BDB010522
|
BDBM224087
C[C@@H]1COCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H30ClN7O3 524.025000 |
LELBPLJNZGDRFT-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224087
|
Local ready
Direct docking supported
|
|
E3L010523
BDB010523
|
BDBM224088
C[C@@H]1COCCN1c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H30ClN7O3 524.025000 |
NHYSNEQKOZESPI-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224088
|
Local ready
Direct docking supported
|
|
E3L010524
BDB010524
|
BDBM224089
C[C@H](O)[C@H](Nc1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)c1ccccc1
|
C30H32ClN7O3 574.085000 |
OAOIGKKHTADXJZ-KGYLXKDPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224089
|
Local ready
Direct docking supported
|
|
E3L010525
BDB010525
|
BDBM224090
C[C@@H]1OC(=O)N(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C31H30ClN7O4 600.079000 |
MVEFUPIHUPANCP-LYXWCMDISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224090
|
Local ready
Direct docking supported
|
|
E3L010526
BDB010526
|
BDBM224091
C[C@@H]1COCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H29ClN8O3 525.013000 |
KRJQMWNXJOJKQA-BZUAXINKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224091
|
Local ready
Direct docking supported
|
|
E3L010527
BDB010527
|
BDBM224092
C[C@@H]1COCCN1c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H29ClN8O3 525.013000 |
NJUOBEJLWSSCOV-BZUAXINKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224092
|
Local ready
Direct docking supported
|
|
E3L010528
BDB010528
|
BDBM224093
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4ccccc4)c32)CC1
|
C31H33N7O3 551.651000 |
GVEIZUGDSOLIAE-HFMPRLQTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224093
|
Local ready
Direct docking supported
|
|
E3L010529
BDB010529
|
BDBM224094
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(-c4ccc(F)cc4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C28H30FN5O2 487.579000 |
AWQNQMVNCBAOBG-IYARVYRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224094
|
Local ready
Direct docking supported
|
|
E3L010530
BDB010530
|
BDBM224095
Cc1cccc(-c2nc(C(=O)O)nc3nc(-c4cc(C(C)C)ccn4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C29H33N5O2 483.616000 |
DVGGJUSCBZFQEM-KESTWPANSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224095
|
Local ready
Direct docking supported
|
|
E3L010531
BDB010531
|
BDBM224096
Cc1cccc(-c2nc(-c3noc(=O)[nH]3)nc3nc(-c4cc(C(C)C)ccn4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C30H33N7O2 523.641000 |
VEFQMMPSVGUIND-KESTWPANSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224096
|
Local ready
Direct docking supported
|
|
E3L010532
BDB010532
|
BDBM224097
CC(C)c1ccnc(-c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C29H30ClN7O2 544.059000 |
MCTIXWMZWXXPLA-IYARVYRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224097
|
Local ready
Direct docking supported
|
|
E3L010533
BDB010533
|
BDBM224098
Cc1cccc(-c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C32H35N7O3 565.678000 |
YIUVKQLYTYPAFD-XTJBDQBJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224098
|
Local ready
Direct docking supported
|
|
E3L010534
BDB010534
|
BDBM224099
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C31H32ClN7O3 586.096000 |
NEZCECGQAZLKFH-SKPFHBQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224099
|
Local ready
Direct docking supported
|
|
E3L010535
BDB010535
|
BDBM224100
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)cc(Cl)c4)c32)CC1
|
C31H31Cl2N7O3 620.541000 |
HXWHSOWBRQOGLC-JXQFQVJHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224100
|
Local ready
Direct docking supported
|
|
E3L010536
BDB010536
|
BDBM224101
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cc(F)cc(Cl)c4)c32)CC1
|
C31H31ClFN7O3 604.086000 |
OBRROBAIPHQGER-JXQFQVJHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224101
|
Local ready
Direct docking supported
|
|
E3L010537
BDB010537
|
BDBM224102
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c32)CC1
|
C31H32ClN7O3 586.096000 |
BTMUCHQZAAVPMT-SKPFHBQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224102
|
Local ready
Direct docking supported
|
|
E3L010538
BDB010538
|
BDBM224103
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(C(=O)O)nc(-c4cccc(Cl)c4)c32)CC1
|
C30H32ClN5O3 546.071000 |
VWJDPKRHKJMTOW-SKPFHBQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224103
|
Local ready
Direct docking supported
|
|
E3L010539
BDB010539
|
BDBM224104
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4F)c32)CC1
|
C31H31ClFN7O3 604.086000 |
XCILUJUNKRQDNG-YDHSSHFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224104
|
Local ready
Direct docking supported
|
|
E3L010540
BDB010540
|
BDBM224105
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4ccc(F)c(Cl)c4)c32)CC1
|
C31H31ClFN7O3 604.086000 |
POFWJWBVFZZSAW-JXQFQVJHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224105
|
Local ready
Direct docking supported
|