| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010461
BDB010461
|
BDBM223771
C[C@@H](Nc1nc(CO)nc2nc(N3CCOC[C@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H33F3N6O2 566.628000 |
OOVPUEWKLXVJIU-DVECYGJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223771; PubChem:CID90325104
|
Local ready
Direct docking supported
|
|
E3L010462
BDB010462
|
BDBM223772
CC(C)c1ccnc(-c2nc3nc(CO)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C28H40N6O 476.669000 |
YMKOTNFGKLOUIP-VAMGGRTRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223772
|
Local ready
Direct docking supported
|
|
E3L010463
BDB010463
|
BDBM223773
C[C@@H](Nc1nc(NCCO)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H45N7O2 547.748000 |
LNSPGHSHFLQZHF-FCBCXNLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223773
|
Local ready
Direct docking supported
|
|
E3L010464
BDB010464
|
BDBM223774
C[C@@H](Nc1nc(N2CCC[C@H]2C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C34H47N7O3 601.796000 |
RLQICMIEIRSMIZ-WSCKULIASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223774
|
Local ready
Direct docking supported
|
|
E3L010465
BDB010465
|
BDBM223775
CNc1nc(N[C@H](C)C2CCC2)c2c(n1)nc(N1CCOC[C@H]1c1ccccc1)n2C[C@H]1CC[C@H](C)CC1
|
C30H43N7O 517.722000 |
NCYCMEAXMFMBJM-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223775
|
Local ready
Direct docking supported
|
|
E3L010466
BDB010466
|
BDBM223776
C[C@@H](Nc1nc(N2CCC[C@@H]2C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C34H47N7O3 601.796000 |
RLQICMIEIRSMIZ-FXECQFNTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223776
|
Local ready
Direct docking supported
|
|
E3L010467
BDB010467
|
BDBM223777
C[C@@H](Nc1nc(NC(C)(C)C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C33H47N7O3 589.785000 |
RWYMWEVVXBKHEJ-FCBCXNLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223777
|
Local ready
Direct docking supported
|
|
E3L010468
BDB010468
|
BDBM223983
C[C@@H](Nc1nc(NCC(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H43N7O3 561.731000 |
OKHBNLFQXUKICA-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223983
|
Local ready
Direct docking supported
|
|
E3L010469
BDB010469
|
BDBM223984
COc1ccccc1CN1C[C@H](c2cn(C)c3ccccc23)[C@@H](N(C)C)C1
|
C23H29N3O 363.505000 |
CXQQECCQTKSQKN-IRLDBZIGSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM223984; PubChem:CID124037093
|
Local ready
Direct docking supported
|
|
E3L010470
BDB010470
|
BDBM223985
Cc1cccc(F)c1CN1C[C@H](c2cn(C)c3ccccc23)[C@@H](N(C)C)C1
|
C23H28FN3 365.496000 |
MJNFUMWCOKCILM-OFNKIYASSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM223985; PubChem:CID126962003
|
Local ready
Direct docking supported
|
|
E3L010471
BDB010471
|
BDBM223986
CN(C)[C@H]1CN([C@H]2CCc3cccc(F)c32)C[C@@H]1c1cn(C)c2ccccc12
|
C24H28FN3 377.507000 |
XAWMNFFOVCNWGF-OIBXWCBGSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM223986; PubChem:CID123132216
|
Local ready
Direct docking supported
|
|
E3L010472
BDB010472
|
BDBM223987
CN(C)[C@H]1CN(C2CCc3cccc(F)c32)C[C@@H]1c1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
|
C26H35FN4O2S 486.657000 |
REVJNSVNICWODC-KIDMSAQOSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM223987; PubChem:CID123132213
|
Local ready
Direct docking supported
|
|
E3L010473
BDB010473
|
A-395N
CN(C)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
|
C24H34N4O2S 442.629000 |
VEABDKBNQNHHCB-BJKOFHAPSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM223989; PubChem:CID123132222
|
Local ready
Direct docking supported
|
|
E3L010474
BDB010474
|
BDBM224012
O=C(NCCc1nccs1)c1cnc2c(S)cccc2c1
|
C15H13N3OS2 315.423000 |
MYNGHZGMRXNEEH-UHFFFAOYSA-N | O95630 | STAM-binding protein |
BindingDB, PubChem
BindingDB:BDBM224012; PubChem:CID124081114
|
Local ready
Direct docking supported
|
|
E3L010475
BDB010475
|
BDBM224034
C[C@@H](Nc1nc(N2CCC[C@]2(C)C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C35H49N7O3 615.823000 |
WNIBMAXGDSAJLG-NRWAZYHSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224034
|
Local ready
Direct docking supported
|
|
E3L010476
BDB010476
|
BDBM224035
C[C@@H](Nc1nc(N(C)CC(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H45N7O3 575.758000 |
CCUZMHJLHJDCDO-FCBCXNLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224035
|
Local ready
Direct docking supported
|
|
E3L010477
BDB010477
|
BDBM224036
C[C@@H](Nc1nc(N2CCC(C(=O)O)C2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C34H47N7O3 601.796000 |
WDBSWWOZCDLABO-FYYRUIDDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224036
|
Local ready
Direct docking supported
|
|
E3L010478
BDB010478
|
BDBM224037
CSC1(C(=O)O)CCN(c2nc(N[C@H](C)C3CCC3)c3c(n2)nc(N2CCOC[C@H]2c2ccccc2)n3C[C@H]2CC[C@H](C)CC2)C1
|
C35H49N7O3S 647.890000 |
XEWHEMWKQFHALJ-RAHVYMLLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224037
|
Local ready
Direct docking supported
|
|
E3L010479
BDB010479
|
BDBM224038
C[C@@H](Nc1nc(N2CC(C(=O)O)C(C)(C)C2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C36H51N7O3 629.850000 |
DCPXBYIIAIBMNP-XUZSMEQTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224038
|
Local ready
Direct docking supported
|
|
E3L010480
BDB010480
|
BDBM224039
C[C@@H](Nc1nc(S(C)(=O)=O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C30H42N6O3S 566.772000 |
LIKFDTZPTBZJAW-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224039
|
Local ready
Direct docking supported
|