| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L016621
BDB016621
|
US10246467, Example I-30
C[C@@H]1Oc2c3ccc(C(=O)O)cc3nn2[C@@H]2[C@H]1N(CC1CC1)[C@@]1(C(=O)Nc3cc(Cl)ccc31)[C@H]2c1cccc(Cl)c1F
|
C31H25Cl2FN4O4 607.469000 |
SDVAEDVASKNSQX-ATUJTIGVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374748; PubChem:CID130376447
|
Local ready
Direct docking supported
|
|
E3L016622
BDB016622
|
US10246467, Example I-31
C[C@@H]1Oc2c3ccc(C(=O)O)cc3nn2[C@H]2[C@@H]1N(CC1CC1)[C@]1(C(=O)Nc3cc(Cl)ccc31)[C@@H]2c1cccc(Cl)c1F
|
C31H25Cl2FN4O4 607.469000 |
SDVAEDVASKNSQX-LTUPPYKUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374749; PubChem:CID130376449
|
Local ready
Direct docking supported
|
|
E3L016623
BDB016623
|
US10246467, Example I-32
CC(C)(C)CN1[C@H]2COc3c4ccc(C(=O)O)cc4nn3[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C31H27Cl2FN4O4 609.485000 |
XDVHTKVLJNJURH-ISKXDESKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374750; PubChem:CID130376448
|
Local ready
Direct docking supported
|
|
E3L016624
BDB016624
|
US10246467, Example I-34
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CCC2CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H25Cl2FN4O4 607.469000 |
MHHRAGZRYUZXQG-NCRFVDKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374752; PubChem:CID130376450
|
Local ready
Direct docking supported
|
|
E3L016625
BDB016625
|
US10246467, Example I-36
CC(C)CN1[C@H]2COc3c4ccc(C(=O)O)cc4nn3[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C30H25Cl2FN4O4 595.458000 |
BFYPYKNJQADWEI-HLNVOFQHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374753; PubChem:CID130376451
|
Local ready
Direct docking supported
|
|
E3L016626
BDB016626
|
US10246467, Example I-38
CC(C)CN1[C@@H]2COc3c4ccc(C(=O)O)cc4nn3[C@@H]2[C@@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C30H25Cl2FN4O4 595.458000 |
BFYPYKNJQADWEI-NFDQLLMUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374755; PubChem:CID130376452
|
Local ready
Direct docking supported
|
|
E3L016627
BDB016627
|
US10246467, Example I-39
CC(C)CCN1[C@H]2COc3c4ccc(C(=O)O)cc4nn3[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C31H27Cl2FN4O4 609.485000 |
RQPNXVDALDRZEU-NCRFVDKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374756; PubChem:CID130376453
|
Local ready
Direct docking supported
|
|
E3L016628
BDB016628
|
BDBM374757
[C]C([C])=[C][C]N1[C@H]2[C]Oc3c4ccc(C([O])=O)cc4nn3[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)[N]c1cc(Cl)ccc12
|
C31H12Cl2FN4O4 594.365000 |
SRYQBEOZBPUUAU-NCRFVDKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM374757
|
Local ready
Direct docking supported
|
|
E3L016629
BDB016629
|
US10246467, Example I-43
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CC2CCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H25Cl2FN4O4 607.469000 |
QTSMRTNOGFBVTO-NCRFVDKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374758; PubChem:CID130376455
|
Local ready
Direct docking supported
|
|
E3L016630
BDB016630
|
US10246467, Example I-45
CC1CC1CN1[C@H]2COc3c4ccc(C(=O)O)cc4nn3[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C31H25Cl2FN4O4 607.469000 |
IIMKYIXMERGUPL-MPLCTNQTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374759; PubChem:CID130376456
|
Local ready
Direct docking supported
|
|
E3L016631
BDB016631
|
US10246467, Example I-47
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CC2CC2(F)F)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C30H21Cl2F3N4O4 629.422000 |
RLUCXXWXLKLQLP-UPKXIKCVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374760; PubChem:CID130376457
|
Local ready
Direct docking supported
|
|
E3L016632
BDB016632
|
US10246467, Example I-49
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CC2CCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C32H27Cl2FN4O4 621.496000 |
BUHMVSNQRFYGLY-CKHSQSCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374761; PubChem:CID130376458
|
Local ready
Direct docking supported
|
|
E3L016633
BDB016633
|
US10246467, Example I-51
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CC2CCOC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H25Cl2FN4O5 623.468000 |
YIWFNWHPCSUTPI-BATIDXRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374762; PubChem:CID130376461
|
Local ready
Direct docking supported
|
|
E3L016634
BDB016634
|
US10246467, Example I-53
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CC2CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C33H29Cl2FN4O4 635.523000 |
MNVZMEAGKBVOJJ-LMFMZMNVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374763; PubChem:CID130376459
|
Local ready
Direct docking supported
|
|
E3L016635
BDB016635
|
US10246467, Example I-55
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(C2CCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H25Cl2FN4O4 607.469000 |
UNARVQRBYFEWAI-NCRFVDKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374764; PubChem:CID130376460
|
Local ready
Direct docking supported
|
|
E3L016636
BDB016636
|
US10246467, Example I-57
C[C@H]1CC(N2[C@H]3COc4c5ccc(C(=O)O)cc5nn4[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)C[C@@H]1C
|
C33H29Cl2FN4O4 635.523000 |
KPYXMBNMDIMBLZ-LTBSGKJHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374765; PubChem:CID130376465
|
Local ready
Direct docking supported
|
|
E3L016637
BDB016637
|
US10246467, Example I-59
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(C2CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C32H27Cl2FN4O4 621.496000 |
WYGAHHDMOLTFMI-CKHSQSCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374766; PubChem:CID130376463
|
Local ready
Direct docking supported
|
|
E3L016638
BDB016638
|
US10246467, Example I-61
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(C2CCCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C33H29Cl2FN4O4 635.523000 |
RNOLLUXAEDHXDC-LMFMZMNVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374767; PubChem:CID130376462
|
Local ready
Direct docking supported
|
|
E3L016639
BDB016639
|
US10246467, Example I-63
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CC2CCCOC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C32H27Cl2FN4O5 637.495000 |
JHYFYTRJNSSZAS-LUJRYGLYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374768; PubChem:CID130376464
|
Local ready
Direct docking supported
|
|
E3L016640
BDB016640
|
US10246467, Example I-65
O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](CO3)N(CC2CCOCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C32H27Cl2FN4O5 637.495000 |
WFZLRDBQPDMPPE-CKHSQSCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM374769; PubChem:CID130376466
|
Local ready
Direct docking supported
|