| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L018801
BDB018801
|
US10669234, Example 11
COc1ccccc1-c1cccc2c1CCN2C(=O)[C@@H]1CCCN1C#N
|
C21H21N3O2 347.418000 |
LMVCADKTOPZYBN-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445072; PubChem:CID140885151
|
Local ready
Direct docking supported
|
|
E3L018802
BDB018802
|
3-(1-(cyano-L-prolyl)indolin-4-yl)-N-methylbenzamide
CNC(=O)c1cccc(-c2cccc3c2CCN3C(=O)[C@@H]2CCCN2C#N)c1
|
C22H22N4O2 374.444000 |
CRDCHCGQXWFHMG-FQEVSTJZSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445073; PubChem:CID140885159
|
Local ready
Direct docking supported
|
|
E3L018803
BDB018803
|
BDBM445074
N#CN1CCC[C@H]1C(=O)N1CCc2c(C3CC3)cccc21
|
C17H19N3O 281.359000 |
AHXHFWKYIYXQMV-INIZCTEOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445074; PubChem:CID140885139
|
Local ready
Direct docking supported
|
|
E3L018804
BDB018804
|
US10669234, Example 14
CO[C@H]1C[C@@H](C(=O)N2CCc3c(-c4ccccc4)cccc32)N(C#N)C1
|
C21H21N3O2 347.418000 |
DJQHWGVEXLMBAZ-JXFKEZNVSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445075; PubChem:CID124197518
|
Local ready
Direct docking supported
|
|
E3L018805
BDB018805
|
US10669234, Example 15
CO[C@@H]1C[C@@H](C(=O)N2CCc3c(-c4ccccc4)cccc32)N(C#N)C1
|
C21H21N3O2 347.418000 |
DJQHWGVEXLMBAZ-UZLBHIALSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445076; PubChem:CID140318280
|
Local ready
Direct docking supported
|
|
E3L018806
BDB018806
|
US10669234, Example 16
Cc1oncc1-c1ccc2c(c1)CCN2C(=O)[C@@H]1CCCN1C#N
|
C18H18N4O2 322.368000 |
VQXZQBLOCQIOOC-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445077; PubChem:CID140885166
|
Local ready
Direct docking supported
|
|
E3L018807
BDB018807
|
BDBM445078
N#CN1CCC[C@H]1C(=O)N1CCc2cc(-c3ccccc3)ccc21
|
C20H19N3O 317.392000 |
PTEPIQYGZOAPCJ-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445078; PubChem:CID140885165
|
Local ready
Direct docking supported
|
|
E3L018808
BDB018808
|
BDBM445079
N#CN1CCC[C@H]1C(=O)N1CCc2cc(-c3cn[nH]c3C(F)(F)F)ccc21
|
C18H16F3N5O 375.354000 |
FYIRZBLRACCKNX-HNNXBMFYSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445079; PubChem:CID135205527
|
Local ready
Direct docking supported
|
|
E3L018809
BDB018809
|
US10669234, Example 19
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3cn[nH]c3C(F)(F)F)cccc21
|
C18H16F3N5O 375.354000 |
AIDJSSPSMPDBMV-HNNXBMFYSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445080; PubChem:CID124197627
|
Local ready
Direct docking supported
|
|
E3L018810
BDB018810
|
US10669234, Example 20
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3cn[nH]c3)cccc21
|
C17H17N5O 307.357000 |
AZVYCCRALWFRRD-INIZCTEOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445081; PubChem:CID124197479
|
Local ready
Direct docking supported
|
|
E3L018811
BDB018811
|
US10669234, Example 21
Cc1[nH]ncc1-c1cccc2c1CCN2C(=O)[C@@H]1CCCN1C#N
|
C18H19N5O 321.384000 |
FVZXOSYEKUHRSU-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445082; PubChem:CID124197482
|
Local ready
Direct docking supported
|
|
E3L018812
BDB018812
|
US10669234, Example 22
N#Cc1ccc(-c2cccc3c2CCN3C(=O)[C@@H]2CCCN2C#N)cc1
|
C21H18N4O 342.402000 |
LURHVDXFRRUNIS-FQEVSTJZSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445083; PubChem:CID140885137
|
Local ready
Direct docking supported
|
|
E3L018813
BDB018813
|
US10669234, Example 23
N#Cc1cccc(-c2cccc3c2CCN3C(=O)[C@@H]2CCCN2C#N)c1
|
C21H18N4O 342.402000 |
WNYLPSCEQVXVEU-FQEVSTJZSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445084; PubChem:CID140885174
|
Local ready
Direct docking supported
|
|
E3L018814
BDB018814
|
US10669234, Example 24
N#Cc1ccccc1-c1cccc2c1CCN2C(=O)[C@@H]1CCCN1C#N
|
C21H18N4O 342.402000 |
WLUCIYYGHLKLSV-FQEVSTJZSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445085; PubChem:CID140885148
|
Local ready
Direct docking supported
|
|
E3L018815
BDB018815
|
BDBM445086
Cc1n[nH]c(C)c1-c1cccc2c1CCN2C(=O)[C@@H]1CCCN1C#N
|
C19H21N5O 335.411000 |
SAJCGIOIIFCNBN-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445086; PubChem:CID135204464
|
Local ready
Direct docking supported
|
|
E3L018816
BDB018816
|
BDBM445087
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3cc[nH]n3)cccc21
|
C17H17N5O 307.357000 |
IBZCVKYHIYJHBO-INIZCTEOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445087; PubChem:CID135205530
|
Local ready
Direct docking supported
|
|
E3L018817
BDB018817
|
US10669234, Example 27
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3c[nH]c4ncccc34)cccc21
|
C21H19N5O 357.417000 |
PJYJFXAKGZEDNG-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445088; PubChem:CID135205943
|
Local ready
Direct docking supported
|
|
E3L018818
BDB018818
|
US10669234, Example 28
N#CN1CC(F)(F)C[C@H]1C(=O)N1CCc2c(-c3cn[nH]c3C(F)(F)F)cccc21
|
C18H14F5N5O 411.334000 |
BHILSXATFZMXGG-AWEZNQCLSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445089; PubChem:CID135205478
|
Local ready
Direct docking supported
|
|
E3L018819
BDB018819
|
US10669234, Example 29
N#CN1C[C@@H](F)C[C@H]1C(=O)N1CCc2c(-c3cn[nH]c3C(F)(F)F)cccc21
|
C18H15F4N5O 393.344000 |
AHCBJXSHVXHGHF-BONVTDFDSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445090; PubChem:CID135204674
|
Local ready
Direct docking supported
|
|
E3L018820
BDB018820
|
US10669234, Example 30
Cc1[nH]ncc1-c1cccc2c1CCN2C(=O)[C@@H]1CC(F)(F)CN1C#N
|
C18H17F2N5O 357.364000 |
XOANBZMRYZSVBZ-INIZCTEOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445091; PubChem:CID135205376
|
Local ready
Direct docking supported
|