| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L018881
BDB018881
|
US10669234, Example 103
CNC(=O)c1cc(-c2ccccc2Cl)c2c(c1)N(C(=O)[C@@H]1CCCN1C#N)CC2
|
C22H21ClN4O2 408.889000 |
WHFKIEYBBULDCZ-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445152; PubChem:CID135205222
|
Local ready
Direct docking supported
|
|
E3L018882
BDB018882
|
US10669234, Example 104
CNC(=O)c1cc(-c2ccc(Cl)c(Cl)c2)c2c(c1)N(C(=O)[C@@H]1CCCN1C#N)CC2
|
C22H20Cl2N4O2 443.334000 |
HMDPLQQUMZHZRG-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445153; PubChem:CID135205151
|
Local ready
Direct docking supported
|
|
E3L018883
BDB018883
|
US10669234, Example 105
CNC(=O)c1cc(-c2ccc3c(c2)OCO3)c2c(c1)N(C(=O)[C@@H]1CCCN1C#N)CC2
|
C23H22N4O4 418.453000 |
FTDLODJAIMNALU-SFHVURJKSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445154; PubChem:CID135205264
|
Local ready
Direct docking supported
|
|
E3L018884
BDB018884
|
US10669234, Example 109
CCN(C(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)c1nc(-c2cccc(Cl)c2)cs1
|
C21H26ClN3O3S 435.977000 |
IDGCQIKYYGMWLZ-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445155; PubChem:CID124197549
|
Local ready
Direct docking supported
|
|
E3L018885
BDB018885
|
US10669234, Example 110
CN(C(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)c1nc(-c2cncc(Br)c2)cs1
|
C19H23BrN4O3S 467.389000 |
MNTABRMUKGDYMT-HNNXBMFYSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445156; PubChem:CID124197544
|
Local ready
Direct docking supported
|
|
E3L018886
BDB018886
|
US10669234, Example 112
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3cccc(Cl)c3)cccc21
|
C20H18ClN3O 351.837000 |
VMYMUPNFTDKDMR-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445157; PubChem:CID140885134
|
Local ready
Direct docking supported
|
|
E3L018887
BDB018887
|
BDBM445158
N#CN1CCC[C@H]1C(=O)N1Cc2ccc(-c3c[nH]nc3C(F)(F)F)cc2C1
|
C18H16F3N5O 375.354000 |
UJEGNFZIQZQITK-HNNXBMFYSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445158; PubChem:CID135205260
|
Local ready
Direct docking supported
|
|
E3L018888
BDB018888
|
4-(1-(cyano-L-prolyl)indolin-4-yl)nicotinonitrile
N#Cc1cnccc1-c1cccc2c1CCN2C(=O)[C@@H]1CCCN1C#N
|
C20H17N5O 343.390000 |
YXXMBPGLQFRQLH-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445159; PubChem:CID140885157
|
Local ready
Direct docking supported
|
|
E3L018889
BDB018889
|
US10669234, Example 117
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3ccnc4[nH]ccc34)cccc21
|
C21H19N5O 357.417000 |
CRINRUDDKSBHIM-IBGZPJMESA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445160; PubChem:CID135205131
|
Local ready
Direct docking supported
|
|
E3L018890
BDB018890
|
US10669234, Example 118
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3cccc(N)n3)cccc21
|
C19H19N5O 333.395000 |
QWXLOTOMNSXTBW-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445161; PubChem:CID140885147
|
Local ready
Direct docking supported
|
|
E3L018891
BDB018891
|
US10669234, Example 119
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3cncc(N)n3)cccc21
|
C18H18N6O 334.383000 |
YOGAXMPPMMXAEY-INIZCTEOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445162; PubChem:CID140885146
|
Local ready
Direct docking supported
|
|
E3L018892
BDB018892
|
US10669234, Example 120
CNc1nccc(-c2cccc3c2CCN3C(=O)[C@@H]2CCCN2C#N)n1
|
C19H20N6O 348.410000 |
QXXVNRVLJDODMU-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445163; PubChem:CID140885138
|
Local ready
Direct docking supported
|
|
E3L018893
BDB018893
|
US10669234, Example 121
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3cnc(N)nc3)cccc21
|
C18H18N6O 334.383000 |
PGWVBDMLLJFVDO-INIZCTEOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445164; PubChem:CID140885173
|
Local ready
Direct docking supported
|
|
E3L018894
BDB018894
|
US10669234, Example 122
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3n[nH]c4ncccc34)cccc21
|
C20H18N6O 358.405000 |
ITVHSCOFHWBGHL-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445165; PubChem:CID135205141
|
Local ready
Direct docking supported
|
|
E3L018895
BDB018895
|
US10669234, Example 123
N#CN1CCC[C@H]1C(=O)N1CCc2c(-c3c[nH]c4nccnc34)cccc21
|
C20H18N6O 358.405000 |
HFYHHCUUAZHVOR-KRWDZBQOSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445166; PubChem:CID140885162
|
Local ready
Direct docking supported
|
|
E3L018896
BDB018896
|
US10669234, Example 124
CN(C(=O)[C@@H]1CCCN1C#N)c1nc(-c2ccc(F)c(Cl)c2)cs1
|
C16H14ClFN4OS 364.833000 |
HLYWOXLKZGUNLZ-AWEZNQCLSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445167; PubChem:CID135205657
|
Local ready
Direct docking supported
|
|
E3L018897
BDB018897
|
US10669234, Example 125
CN(C(=O)[C@@H]1CCCN1C#N)c1nc(-c2cccc(C(F)(F)F)c2)cs1
|
C17H15F3N4OS 380.395000 |
JQYNODAUGQIMPL-AWEZNQCLSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445168; PubChem:CID135204760
|
Local ready
Direct docking supported
|
|
E3L018898
BDB018898
|
US10669234, Example 126
CN(C(=O)[C@@H]1CCCN1C#N)c1nc(-c2cccc(C#N)c2)cs1
|
C17H15N5OS 337.408000 |
LJALYPZMAKFPSM-HNNXBMFYSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM445169; PubChem:CID135204796
|
Local ready
Direct docking supported
|
|
E3L018899
BDB018899
|
US10696655, Example 1
CNC(=O)N1CCOc2ccc(-c3nccc4ccccc34)cc2C1
|
C20H19N3O2 333.391000 |
DTVDVNBQAJTARO-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM448528; PubChem:CID132169488
|
Local ready
Direct docking supported
|
|
E3L018900
BDB018900
|
US10696655, Example 2
CNC(=O)N1CCOc2ccc(-c3nc(N)cc4cnccc34)cc2C1
|
C19H19N5O2 349.394000 |
CTSRZBZJYQPTNA-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM448529; PubChem:CID132181510
|
Local ready
Direct docking supported
|