| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L002281
BDB002281
|
BDBM43488
Cc1cc(C)nc(S/C=C/C(=O)c2ccccc2F)n1
|
C15H13FN2OS 288.347000 |
OGBFBWFKVLKSIE-BQYQJAHWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43488; PubChem:CID5713206
|
Local ready
Direct docking supported
|
|
E3L002282
BDB002282
|
BDBM43489
Cc1cc(C)nc(S/C=C/C(=O)c2ccccc2)n1
|
C15H14N2OS 270.357000 |
MKKFBMMVSZMAGN-CMDGGOBGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43489; PubChem:CID5713202
|
Local ready
Direct docking supported
|
|
E3L002283
BDB002283
|
BDBM43490
Cc1cc(C)nc(S/C=C/C(=O)c2ccc(F)cc2)n1
|
C15H13FN2OS 288.347000 |
IIDUVXPAMLZRAI-BQYQJAHWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43490; PubChem:CID5713207
|
Local ready
Direct docking supported
|
|
E3L002284
BDB002284
|
BDBM43491
COc1cc(/C=C2\COC/C(=C\c3cc(OC)c(OC)c(OC)c3)C2=O)cc(OC)c1OC
|
C25H28O8 456.491000 |
WDUOPQZLRWPGTF-ZEELXFFVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43491; PubChem:CID5703458
|
Local ready
Direct docking supported
|
|
E3L002285
BDB002285
|
BDBM43492
O=C1CN(c2cc(Cl)cc(Cl)c2)C(=O)CN1N=Cc1cccnc1
|
C16H12Cl2N4O2 363.204000 |
BANGKJLPWMUBFY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM43492
|
Local ready
Direct docking supported
|
|
E3L002286
BDB002286
|
N-[4-(thiadiazol-4-yl)phenyl]cyclopropanecarboxamide
O=C(Nc1ccc(-c2csnn2)cc1)C1CC1
|
C12H11N3OS 245.307000 |
GEBZKAGTZLMKSR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43493; PubChem:CID2739181
|
Local ready
Direct docking supported
|
|
E3L002287
BDB002287
|
BDBM43494
O=C(CSC1=NNC(c2ccccn2)S1)Nc1ccc(C(F)(F)F)cc1
|
C16H13F3N4OS2 398.435000 |
DHPJRZFBJOWYTH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43494; PubChem:CID2746661
|
Local ready
Direct docking supported
|
|
E3L002288
BDB002288
|
BDBM43495
c1ccc(CSC2=NNC(c3ccccn3)S2)cc1
|
C14H13N3S2 287.413000 |
IQZPEFTWPLGMGB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43495; PubChem:CID2746653
|
Local ready
Direct docking supported
|
|
E3L002289
BDB002289
|
BDBM43496
CN1C(C(=O)NCc2cccc(Br)c2)CC2Cn3c(nc4cc5ccccc5cc43)C21
|
C25H23BrN4O 475.390000 |
IHBDJYMHOLWISV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43496; PubChem:CID16745983
|
Local ready
Direct docking supported
|
|
E3L002290
BDB002290
|
BDBM43497
CC(C)n1cnc2c(N(C)c3ccccc3)nc(N(CCN(C)C)Cc3ccccc3)nc21
|
C26H33N7 443.599000 |
NODXLMGAZSOUEJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43497; PubChem:CID16746000
|
Local ready
Direct docking supported
|
|
E3L002291
BDB002291
|
BDBM43498
O=C1CCN(Cc2ccccc2)S(=O)(=O)c2ccccc21
|
C16H15NO3S 301.367000 |
GKJYNLWSBFLPRT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43498; PubChem:CID16060207
|
Local ready
Direct docking supported
|
|
E3L002292
BDB002292
|
BDBM43499
C=C1CCN(C(C(=O)OC)C(C)C)S(=O)(=O)c2ccccc21
|
C16H21NO4S 323.414000 |
SSSFJPMLEMOLRG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43499; PubChem:CID16746545
|
Local ready
Direct docking supported
|
|
E3L002293
BDB002293
|
1H-Benzo(a)carbazole-1,4-dione, 8,11-dimethyl-
Cc1ccc2c(c1)c1ccc3c(c1n2C)C(=O)C=CC3=O
|
C18H13NO2 275.307000 |
XDWNNOGYJWNAAV-UHFFFAOYSA-N | O14727, Q00987 | E3 ubiquitin-protein ligase Mdm2, Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM43500; PubChem:CID378581
|
Local ready
Direct docking supported
|
|
E3L002294
BDB002294
|
BDBM43779
O=C(O)[C@H](Cc1ccccc1)N1Cc2ccccc2C1=O
|
C17H15NO3 281.311000 |
FZEBPJBRDFXKIH-HNNXBMFYSA-N | P98170 | E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM43779; PubChem:CID5309580
|
Local ready
Direct docking supported
|
|
E3L002295
BDB002295
|
2-(4-Fluorophenyl)-2-(1-oxoisoindolin-2-YL)acetic acid
O=C(O)C(c1ccc(F)cc1)N1Cc2ccccc2C1=O
|
C16H12FNO3 285.274000 |
DUIUKBXBDVBIDC-UHFFFAOYSA-N | P98170 | E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM43781; PubChem:CID20855134
|
Local ready
Direct docking supported
|
|
E3L002296
BDB002296
|
2-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CC(C(=O)O)N1Cc2ccccc2C1=O
|
C11H11NO3 205.213000 |
XBPWPQBDGZFHQI-UHFFFAOYSA-N | P98170 | E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM43782; PubChem:CID2764373
|
Local ready
Direct docking supported
|
|
E3L002297
BDB002297
|
BDBM43833
CC1(C)CC(=O)C=C(NNC(=O)c2ccccc2O)C1
|
C15H18N2O3 274.320000 |
KFDZBIOHUZHVNU-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM43833; PubChem:CID749340
|
Local ready
Direct docking supported
|
|
E3L002298
BDB002298
|
BDBM43838
COC(=O)CCC(=O)OC1(C)C(=O)C2=CN(C3CC3)C(c3ccc(OC)cc3)=CC2=C(Br)C1=O
|
C25H24BrNO7 530.371000 |
ZWILRIIIGUBNDA-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM43838; PubChem:CID16759689
|
Local ready
Direct docking supported
|
|
E3L002299
BDB002299
|
BDBM44254
CNC(C)C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NCCCCCNC(=O)C(NC(=O)C1CCCN1C(=O)C(NC(=O)C(C)NC)C1CCCCC1)C(c1ccccc1)c1ccccc1)C(c1ccccc1)c1ccccc1)C1CCCCC1
|
C69H94N10O8 1191.573000 |
IUINTNIAONPYCX-UHFFFAOYSA-N | P98170 | E3 ubiquitin-protein ligase XIAP |
BindingDB
BindingDB:BDBM44254
|
Local ready
Direct docking supported
|
|
E3L002300
BDB002300
|
BDBM44255
CNC(C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1)C(C)(C)C
|
C28H38N4O3 478.637000 |
IJVMSMRIOSLRIP-DGUFBMEBSA-N | P98170 | E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM44255; PubChem:CID25181251
|
Local ready
Direct docking supported
|