| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L002241
BDB002241
|
BDBM43448
Cc1cc2cc(C)c(SCC(=O)NCc3ccco3)nc2cc1C
|
C19H20N2O2S 340.448000 |
NCEHYJDQRHAKDJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43448; PubChem:CID857007
|
Local ready
Direct docking supported
|
|
E3L002242
BDB002242
|
BDBM43449
COc1cc2c(cc1OC)CN(C(=O)c1ccco1)CC2
|
C16H17NO4 287.315000 |
CECGSVVPTWTPAP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43449; PubChem:CID751492
|
Local ready
Direct docking supported
|
|
E3L002243
BDB002243
|
BDBM43450
O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)c1ccc(Cl)nc1)C1CCCCC1
|
C25H31ClN4O2 455.002000 |
CMIUDBSUFRSZNC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43450; PubChem:CID3231070
|
Local ready
Direct docking supported
|
|
E3L002244
BDB002244
|
BDBM43451
CCOC(=O)c1sc(=S)n(-c2ccccc2)c1N(C(C)=O)C(C)=O
|
C16H16N2O4S2 364.448000 |
XNEXLEGCYIIAHF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43451; PubChem:CID3100036
|
Local ready
Direct docking supported
|
|
E3L002245
BDB002245
|
BDBM43452
COc1ccc(C2C(C(=O)N3CCN(C)CC3)c3cc(OC)c(OC)cc3C(=O)N2C)cc1
|
C25H31N3O5 453.539000 |
SBKJWGWXFWYUEX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43452; PubChem:CID4220985
|
Local ready
Direct docking supported
|
|
E3L002246
BDB002246
|
BDBM43453
COc1ccc(-c2cc(C(F)(F)F)nc(S(=O)(=O)CCCC(=O)Nc3cccnc3Cl)n2)cc1OC
|
C22H20ClF3N4O5S 544.939000 |
ZVJBPVOVKFEUJZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43453; PubChem:CID5080789
|
Local ready
Direct docking supported
|
|
E3L002247
BDB002247
|
BDBM43454
COc1ccccc1-c1cc(C(F)(F)F)nc(S(=O)(=O)CCCC(=O)Nc2cccnc2Cl)n1
|
C21H18ClF3N4O4S 514.913000 |
RGEBHFBBSLVSRR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43454; PubChem:CID3441150
|
Local ready
Direct docking supported
|
|
E3L002248
BDB002248
|
BDBM43455
CC1=C(C(=O)NC(C)CCc2ccccc2)C2(CCC(C)CC2)OC1=O
|
C22H29NO3 355.478000 |
KMYCZKWWYWTWHE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43455; PubChem:CID16193326
|
Local ready
Direct docking supported
|
|
E3L002249
BDB002249
|
BDBM43456
Cc1cc(C(=O)Nc2cccc3ccccc23)n(-c2ccccc2)n1
|
C21H17N3O 327.387000 |
BFOPHTONFPIIPJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43456; PubChem:CID16193366
|
Local ready
Direct docking supported
|
|
E3L002250
BDB002250
|
BDBM43457
O=C(/C=C/c1cccc([N+](=O)[O-])c1)n1cnc2ccccc21
|
C16H11N3O3 293.282000 |
VYEZXHFIAHYAAP-CMDGGOBGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43457; PubChem:CID5757382
|
Local ready
Direct docking supported
|
|
E3L002251
BDB002251
|
BDBM43458
O=C(CSc1ccc(-c2ccco2)nn1)NC1CCCC1
|
C15H17N3O2S 303.387000 |
NDAJURCJZUVTDG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43458; PubChem:CID7207106
|
Local ready
Direct docking supported
|
|
E3L002252
BDB002252
|
BDBM43459
COC(=O)c1c(-c2ccccc2Cl)noc1/C=C/N(C)C
|
C15H15ClN2O3 306.749000 |
SRHXBSJTLUSGKP-CMDGGOBGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43459; PubChem:CID1476895
|
Local ready
Direct docking supported
|
|
E3L002253
BDB002253
|
6-(methoxymethyl)-2-phenyl-N-propyl-4-pyrimidinamine
CCCNc1cc(COC)nc(-c2ccccc2)n1
|
C15H19N3O 257.337000 |
XCZWBMGZDSGDRI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43460; PubChem:CID4314667
|
Local ready
Direct docking supported
|
|
E3L002254
BDB002254
|
BDBM43461
Cc1nc(CSc2nsc(/C=C/N(C)C)c2C#N)cs1
|
C13H14N4S3 322.484000 |
XYBRJWVFFYKABN-SNAWJCMRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43461; PubChem:CID5773281
|
Local ready
Direct docking supported
|
|
E3L002255
BDB002255
|
BDBM43462
Cn1cc/c(=N\C=C(C#N)C#N)c2ccccc21
|
C14H10N4 234.262000 |
ORVZFBOINIDDAY-GHRIWEEISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM43462
|
Local ready
Direct docking supported
|
|
E3L002256
BDB002256
|
BDBM43463
COc1ccc(C[S+]([O-])C(Cl)=C(Cl)C(=O)Nc2ccc(OC)nc2)cc1
|
C17H16Cl2N2O4S 415.298000 |
SFXGKNBNDTZBEW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43463; PubChem:CID3755871
|
Local ready
Direct docking supported
|
|
E3L002257
BDB002257
|
BDBM43464
COc1ccc(S(=O)(=O)NN(C)c2ncc(C(F)(F)F)cc2Cl)cc1
|
C14H13ClF3N3O3S 395.790000 |
IKHPFBACYMOZSP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43464; PubChem:CID1476492
|
Local ready
Direct docking supported
|
|
E3L002258
BDB002258
|
BDBM43465
COc1ccc(NC(=O)C(Cl)=C(Cl)[S+]([O-])Cc2ccc(Cl)cc2)cn1
|
C16H13Cl3N2O3S 419.717000 |
YHPGXJXWMDNSDU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43465; PubChem:CID3709819
|
Local ready
Direct docking supported
|
|
E3L002259
BDB002259
|
BDBM43466
CSc1nsc(CC=Nc2ccc(F)cc2)c1C#N
|
C13H10FN3S2 291.376000 |
WJMOSRXFIFJMFS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43466; PubChem:CID91896565
|
Local ready
Direct docking supported
|
|
E3L002260
BDB002260
|
BDBM43467
CCOC(=O)C1C(c2ccccc2)N(C)OC1(O)C(F)(F)F
|
C14H16F3NO4 319.279000 |
GLBJBXFOTOHOLE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43467; PubChem:CID2766902
|
Local ready
Direct docking supported
|