| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L002261
BDB002261
|
BDBM43468
O=C(Cc1ccc(-n2c(=O)c3ccccc3n(Cc3ccccc3Cl)c2=O)cc1)NCC1CCCO1
|
C28H26ClN3O4 503.986000 |
HIMUGHHKLHWEQM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43468; PubChem:CID16195160
|
Local ready
Direct docking supported
|
|
E3L002262
BDB002262
|
N,N'-Di-4-pyridinylurea
O=C(Nc1ccncc1)Nc1ccncc1
|
C11H10N4O 214.228000 |
QRRGJASIECDXQW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43469; PubChem:CID1082704
|
Local ready
Direct docking supported
|
|
E3L002263
BDB002263
|
BDBM43470
COc1ccc(OCC(=O)N[N-][C+](C)CC(=O)Nc2cccc([N+](=O)[O-])c2)cc1
|
C19H20N4O6 400.391000 |
PNNWIGBZTXOBMC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM43470
|
Local ready
Direct docking supported
|
|
E3L002264
BDB002264
|
BDBM43471
CCOc1ccc(NC(=O)CN(C)S(=O)(=O)c2c[nH]cn2)cc1
|
C14H18N4O4S 338.389000 |
SXJOGNYDYHHABL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43471; PubChem:CID16011827
|
Local ready
Direct docking supported
|
|
E3L002265
BDB002265
|
BDBM43472
O=C1NC(=O)c2cc(NC(=O)C3COc4ccccc4O3)ccc21
|
C17H12N2O5 324.292000 |
UTADGGLIHPQPNU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43472; PubChem:CID4641353
|
Local ready
Direct docking supported
|
|
E3L002266
BDB002266
|
(5-Phenyl-1,3,4-oxadiazol-2-yl)-thiophen-2-ylmethanol
OC(c1nnc(-c2ccccc2)o1)c1cccs1
|
C13H10N2O2S 258.302000 |
OTYYVUDRHQDNBY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43473; PubChem:CID4964129
|
Local ready
Direct docking supported
|
|
E3L002267
BDB002267
|
BDBM43474
CCN1C/C(=C/c2ccc(OC)c(O)c2)C(=O)/C(=C/c2ccc(OC)c(O)c2)C1
|
C23H25NO5 395.455000 |
UDVWXXKUVFFLEB-BUOZRGFLSA-N | O15151, Q00987, Q99728 | BRCA1-associated RING domain protein 1, E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM43474; PubChem:CID2376815
|
Local ready
Direct docking supported
|
|
E3L002268
BDB002268
|
BDBM43475
Nc1cccc2c1C(=O)N(C(=O)/C=C/c1cccc(Br)c1)C2=O
|
C17H11BrN2O3 371.190000 |
DGFNGIZXCZHTQK-BQYQJAHWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43475; PubChem:CID5854374
|
Local ready
Direct docking supported
|
|
E3L002269
BDB002269
|
BDBM43476
Cc1ccc(C=C2C(Cl)=C(Cl)C(Cl)=C2Cl)cc1
|
C13H8Cl4 306.019000 |
GLCNSQWOANYMNW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43476; PubChem:CID230812
|
Local ready
Direct docking supported
|
|
E3L002270
BDB002270
|
1,5-Dipyridin-3-ylpenta-1,4-dien-3-one
O=C(C=Cc1cccnc1)C=Cc1cccnc1
|
C15H12N2O 236.274000 |
UWILVEPRHIRCJK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43477; PubChem:CID288321
|
Local ready
Direct docking supported
|
|
E3L002271
BDB002271
|
BDBM43478
CN(C)c1n/c(=N/Cc2ccco2)ss1
|
C9H11N3OS2 241.341000 |
IIINLXGWSVXPIL-NTMALXAHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM43478
|
Local ready
Direct docking supported
|
|
E3L002272
BDB002272
|
Ethyl 3,5-dibenzylidene-4-oxopiperidine-1-carboxylate
CCOC(=O)N1CC(=Cc2ccccc2)C(=O)C(=Cc2ccccc2)C1
|
C22H21NO3 347.414000 |
DJIOYGAIBLADNB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43479; PubChem:CID364404
|
Local ready
Direct docking supported
|
|
E3L002273
BDB002273
|
11H-Benzo[a]carbazole-1,4-dione, 7,11-dimethyl-
Cc1cccc2c1c1ccc3c(c1n2C)C(=O)C=CC3=O
|
C18H13NO2 275.307000 |
HYPOPXGVJOVIPH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43480; PubChem:CID371271
|
Local ready
Direct docking supported
|
|
E3L002274
BDB002274
|
BDBM43481
O=C1N=c2ccccc2=C1NNC(=S)N1CCOCC1
|
C13H14N4O2S 290.348000 |
BOPKOOPFDUKJCB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM43481
|
Local ready
Direct docking supported
|
|
E3L002275
BDB002275
|
6-O-Acetylhelenalin
C=C1C(=O)O[C@@H]2C[C@@H](C)[C@@H]3C=CC(=O)[C@@]3(C)[C@@H](OC(C)=O)[C@H]12
|
C17H20O5 304.342000 |
DCNRYQODUSSOKC-HKHYKUHTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43482; PubChem:CID442142
|
Local ready
Direct docking supported
|
|
E3L002276
BDB002276
|
Aromaticin
C=C1C(=O)O[C@H]2C[C@@H](C)[C@@H]3C=CC(=O)[C@@]3(C)C[C@H]12
|
C15H18O3 246.306000 |
OSSDUQKWVVZIGP-SCGWIAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43483; PubChem:CID282529
|
Local ready
Direct docking supported
|
|
E3L002277
BDB002277
|
Helenalin
C=C1C(=O)O[C@@H]2C[C@@H](C)[C@@H]3C=CC(=O)[C@@]3(C)[C@@H](O)[C@H]12
|
C15H18O4 262.305000 |
ZVLOPMNVFLSSAA-XEPQRQSNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43484; PubChem:CID23205
|
Local ready
Direct docking supported
|
|
E3L002278
BDB002278
|
2,3-Epoxy-helenalin
C=C1C(=O)O[C@@H]2C[C@@H](C)[C@@H]3C4OC4C(=O)[C@@]3(C)[C@@H](O)[C@H]12
|
C15H18O5 278.304000 |
QVBODYCYOLPPMA-NNIVYTCXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43485; PubChem:CID16745538
|
Local ready
Direct docking supported
|
|
E3L002279
BDB002279
|
BDBM43486
COC(=O)C1=C(C(=O)OC)[C@@H]2N(C)c3ccc(OC)cc3[C@@]23C[C@@H](C(=O)OC)N=C3N1
|
C21H23N3O7 429.429000 |
YLGLBGPCVQKLMK-SAZGQGMLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43486; PubChem:CID16759750
|
Local ready
Direct docking supported
|
|
E3L002280
BDB002280
|
BDBM43487
COc1cc(NC(=O)c2cnc(N)s2)cc(C(=O)Nc2cccc(C(F)(F)F)c2)c1
|
C19H15F3N4O3S 436.415000 |
HZCWSBQOFBJTKS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43487; PubChem:CID16745806
|
Local ready
Direct docking supported
|