| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L025521
BDB025521
|
US11312723, Example 204
Cc1cccc2c1NCC[C@@H]2C(=O)n1nc2c(c1N)CCN(CCO)C2
|
C19H25N5O2 355.442000 |
PZWQMRHZXWXBJD-AWEZNQCLSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM552028; PubChem:CID155643098
|
Local ready
Direct docking supported
|
|
E3L025522
BDB025522
|
US11312723, Example 205
Cc1cccc2c1NCC[C@H]2C(=O)n1nc2c(c1N)CCN(CCO)C2
|
C19H25N5O2 355.442000 |
PZWQMRHZXWXBJD-CQSZACIVSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM552029; PubChem:CID155330732
|
Local ready
Direct docking supported
|
|
E3L025523
BDB025523
|
WO2022103411, Example S1
CC(C)[C@@H](C(=O)N1C[C@H](O)CC1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C2CC2)nn1
|
C30H36N6O4 544.656000 |
ONVKLPZAABEJOY-ZVAIXIBVSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552683; PubChem:CID164607730
|
Local ready
Direct docking supported
|
|
E3L025524
BDB025524
|
WO2022103411, Example S3
CC(C)(C)[C@@H](C(=O)N1C[C@H](O)CC1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C2CC2)nn1
|
C31H38N6O4 558.683000 |
DPJOJCHWMWBSKQ-JXPRAFDXSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552684; PubChem:CID164607731
|
Local ready
Direct docking supported
|
|
E3L025525
BDB025525
|
WO2022103411, Example S14
CC(=O)NCCOCc1cn([C@H](C(=O)N2C[C@H](O)CC2C(=O)N[C@H](Cc2ccc(-c3ccccc3)cc2)C(N)=O)C(C)(C)C)nn1
|
C33H43N7O6 633.750000 |
ZZWDGXXZRUGUSA-HWMCGDIZSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552685; PubChem:CID164607732
|
Local ready
Direct docking supported
|
|
E3L025526
BDB025526
|
WO2022103411, Example S24
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(C3CC3)nn2)C(C)(C)C)cc1
|
C27H34N6O3S 522.675000 |
KTXIDFFZCOJFLJ-JCTONOIOSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552686; PubChem:CID146151217
|
Local ready
Direct docking supported
|
|
E3L025527
BDB025527
|
WO2022103411, Example S27
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(Cc3ccccc3)nn2)C(C)(C)C)cc1
|
C31H36N6O3S 572.735000 |
HTIYTKHOMNYAKR-FULLSBAXSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552687; PubChem:CID163300581
|
Local ready
Direct docking supported
|
|
E3L025528
BDB025528
|
WO2022103411, Example S2
C[C@@H](C(=O)N1C[C@H](O)CC1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C2CC2)nn1
|
C28H32N6O4 516.602000 |
RCUWCPGQGZBXIJ-KKFMQVGYSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552688; PubChem:CID164607733
|
Local ready
Direct docking supported
|
|
E3L025529
BDB025529
|
WO2022103411, Example S4
NC(=O)[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)C1C[C@@H](O)CN1C(=O)[C@H](C1CCC1)n1cc(C2CC2)nn1
|
C31H36N6O4 556.667000 |
DXCFMJMLSKBAGH-VFLSMOPBSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552689; PubChem:CID164607734
|
Local ready
Direct docking supported
|
|
E3L025530
BDB025530
|
WO2022103411, Example S5
CCC(C)[C@@H](C(=O)N1C[C@H](O)CC1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C2CC2)nn1
|
C31H38N6O4 558.683000 |
GGVMIEIIPMPQOR-VVQZKFCISA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552690; PubChem:CID164607735
|
Local ready
Direct docking supported
|
|
E3L025531
BDB025531
|
WO2022103411, Example S6
CCC(C)(C)[C@@H](C(=O)N1C[C@H](O)CC1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C2CC2)nn1
|
C32H40N6O4 572.710000 |
YANFJUZPCPHVNG-UWXXIFDUSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552691; PubChem:CID164607736
|
Local ready
Direct docking supported
|
|
E3L025532
BDB025532
|
WO2022103411, Example S7
C=CC(C)(C)[C@@H](C(=O)N1C[C@H](O)CC1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C2CC2)nn1
|
C32H38N6O4 570.694000 |
OIQDXSNETXYIIJ-UWXXIFDUSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552692; PubChem:CID164607737
|
Local ready
Direct docking supported
|
|
E3L025533
BDB025533
|
WO2022103411, Example S8
NC(=O)[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)C1C[C@@H](O)CN1C(=O)[C@H](C1C2CC3CC(C2)CC1C3)n1cc(C2CC2)nn1
|
C37H44N6O4 636.797000 |
PMYQGLYLBPCRDP-VSNSSFDBSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552693; PubChem:CID164607738
|
Local ready
Direct docking supported
|
|
E3L025534
BDB025534
|
WO2022103411, Example S9
CC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1ccnn1
|
C28H34N6O4 518.618000 |
SFONCPIWPDSZRH-JLLPCOHGSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552694; PubChem:CID164607739
|
Local ready
Direct docking supported
|
|
E3L025535
BDB025535
|
WO2022103411, Example S10
COCc1cn([C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@H](Cc2ccc(-c3ccccc3)cc2)C(N)=O)C(C)(C)C)nn1
|
C30H38N6O5 562.671000 |
KNYWAKZMVVONRX-FXSWLTOZSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552695; PubChem:CID163300687
|
Local ready
Direct docking supported
|
|
E3L025536
BDB025536
|
WO2022103411, Example S11
CC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(Cc2ccccc2)nn1
|
C35H40N6O4 608.743000 |
CVCDUVOUMONHJI-LTXXGDHTSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552696; PubChem:CID163300723
|
Local ready
Direct docking supported
|
|
E3L025537
BDB025537
|
WO2022103411, Example S12
CC(=O)NCC1(c2cn([C@@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N[C@H](Cc3ccc(-c4ccccc4)cc3)C(N)=O)C(C)(C)C)nn2)CC1
|
C34H43N7O5 629.762000 |
CWWVAMCMVVGTPN-DIBLIPFTSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552697; PubChem:CID163300651
|
Local ready
Direct docking supported
|
|
E3L025538
BDB025538
|
WO2022103411, Example S13
CC(=O)NCC1(c2cn([C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N[C@H](Cc3ccc(-c4ccccc4)cc3)C(N)=O)C(C)(C)C)nn2)CC1
|
C34H43N7O5 629.762000 |
CWWVAMCMVVGTPN-CITHKVLSSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552698; PubChem:CID163300612
|
Local ready
Direct docking supported
|
|
E3L025539
BDB025539
|
WO2022103411, Example S15
CC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C(=O)O)nn1
|
C29H34N6O6 562.627000 |
FYOISBUPTLVIMN-CJTFWIGWSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552699; PubChem:CID163300714
|
Local ready
Direct docking supported
|
|
E3L025540
BDB025540
|
WO2022103411, Example S16
CC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1cc(C(N)=O)nn1
|
C29H35N7O5 561.643000 |
YDQCNPGWFYTEAH-CJTFWIGWSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552700; PubChem:CID163300658
|
Local ready
Direct docking supported
|