| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L025541
BDB025541
|
WO2022103411, Example S17
CNC(=O)c1cn([C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@H](Cc2ccc(-c3ccccc3)cc2)C(N)=O)C(C)(C)C)nn1
|
C30H37N7O5 575.670000 |
JIFYGNWBOUYLMM-YQIMAOPZSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552701; PubChem:CID163300628
|
Local ready
Direct docking supported
|
|
E3L025542
BDB025542
|
WO2022103411, Example S18
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(C3CC3)nn2)C(C)(C)C)cc1
|
C28H36N6O3S 536.702000 |
VPVWYAMEFQFVQS-HFONSACISA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552702; PubChem:CID163300702
|
Local ready
Direct docking supported
|
|
E3L025543
BDB025543
|
WO2022103411, Example S19
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C2CCCCC2)n2cc(C3CC3)nn2)cc1
|
C30H38N6O3S 562.740000 |
CRONOEXIBVALGH-PWXWPJMESA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552703; PubChem:CID163300650
|
Local ready
Direct docking supported
|
|
E3L025544
BDB025544
|
WO2022103411, Example S20
Cc1ncsc1-c1ccc([C@H](C)NC(=O)C2C[C@@H](O)CN2C(=O)[C@H](C2C3CC4CC(C3)CC2C4)n2cc(C3CC3)nn2)cc1
|
C34H42N6O3S 614.816000 |
CNTOTQTYVRMHJR-XHKQKVOQSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552704; PubChem:CID164607740
|
Local ready
Direct docking supported
|
|
E3L025545
BDB025545
|
WO2022103411, Example S21
CCC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(-c2scnc2C)cc1)n1cc(C2CC2)nn1
|
C29H38N6O3S 550.729000 |
WJBFFPMKJCJAHU-HEIHPFCESA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552705; PubChem:CID163300697
|
Local ready
Direct docking supported
|
|
E3L025546
BDB025546
|
WO2022103411, Example S22
Cc1ncsc1-c1ccc(C(C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(C3CC3)nn2)C(C)(C)C)c(Cl)c1
|
C28H35ClN6O3S 571.147000 |
QTGJVZWACMFXDO-BRKKJYDJSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552706; PubChem:CID163300584
|
Local ready
Direct docking supported
|
|
E3L025547
BDB025547
|
WO2022103411, Example S23
Cc1ncsc1-c1ccc(C(C)NC(=O)C2C[C@@H](O)CN2C(=O)[C@H](C2C3CC4CC(C3)CC2C4)n2cc(C3CC3)nn2)c(Cl)c1
|
C34H41ClN6O3S 649.261000 |
DYJLPMZYSNVISA-IILCGFKCSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552707; PubChem:CID164607741
|
Local ready
Direct docking supported
|
|
E3L025548
BDB025548
|
WO2022103411, Example S25
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C2CCCCC2)n2cc(C3CC3)nn2)cc1
|
C29H36N6O3S 548.713000 |
ABLSLRVVJAAZQW-AFESJLNVSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552708; PubChem:CID163300648
|
Local ready
Direct docking supported
|
|
E3L025549
BDB025549
|
WO2022103411, Example S26
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(C3CC3)nn2)C(C)(C)c2ccccc2)cc1
|
C32H36N6O3S 584.746000 |
AIUZLJUPLJVZOV-WGHVJBFBSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552709; PubChem:CID163300613
|
Local ready
Direct docking supported
|
|
E3L025550
BDB025550
|
WO2022103411, Example S28
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(C3(C(F)(F)F)CC3)nn2)C(C)(C)C)cc1
|
C28H33F3N6O3S 590.672000 |
PPDADZSODOQSCQ-ZRCGQRJVSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552710; PubChem:CID163300592
|
Local ready
Direct docking supported
|
|
E3L025551
BDB025551
|
WO2022103411, Example S29
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(C3(C)CC3)nn2)C(C)(C)C)cc1
|
C28H36N6O3S 536.702000 |
JBTOFOFMEKQDIQ-ZFGGDYGUSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552711; PubChem:CID163300653
|
Local ready
Direct docking supported
|
|
E3L025552
BDB025552
|
WO2022103411, Example S30A
C#CC1(c2cn([C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(-c4scnc4C)cc3)C(C)(C)C)nn2)CC1
|
C29H34N6O3S 546.697000 |
LJUZMAPWBQHHSY-OTNCWRBYSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552712; PubChem:CID164607742
|
Local ready
Direct docking supported
|
|
E3L025553
BDB025553
|
WO2022103411, Example S30B
Cc1ncsc1-c1ccc(CNC(=O)C2C[C@H](O)CN2C(=O)[C@@H](n2cc(C3(c4cn([C@H](C(=O)N5C[C@H](O)C[C@H]5C(=O)NCc5ccc(-c6scnc6C)cc5)C(C)(C)C)nn4)CC3)nn2)C(C)(C)C)cc1
|
C51H62N12O6S2 1003.269000 |
VLVSRCRLXUJKJW-NSIITZEYSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552713; PubChem:CID164607743
|
Local ready
Direct docking supported
|
|
E3L025554
BDB025554
|
WO2022103411, Example S31
Cc1cn([C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@H](Cc2ccc(-c3ccccc3)cc2)C(N)=O)C(C)C)nn1
|
C28H34N6O4 518.618000 |
BJTNDMJUEGKMQJ-NGSHPTGOSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552714; PubChem:CID164607744
|
Local ready
Direct docking supported
|
|
E3L025555
BDB025555
|
WO2022103411, Example S32
Cc1cnnn1[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)C(C)C
|
C28H34N6O4 518.618000 |
BZTVJVSBWHFDKV-NGSHPTGOSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552715; PubChem:CID164607745
|
Local ready
Direct docking supported
|
|
E3L025556
BDB025556
|
WO2022103411, Example S33A
COC(=O)c1nnn([C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@H](Cc2ccc(-c3ccccc3)cc2)C(N)=O)C(C)C)c1C
|
C30H36N6O6 576.654000 |
JNIPXVOIXDHQRS-BIATYSSJSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552716; PubChem:CID164607746
|
Local ready
Direct docking supported
|
|
E3L025557
BDB025557
|
WO2022103411, Example S33B
COC(=O)c1nnn([C@@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@H](Cc2ccc(-c3ccccc3)cc2)C(N)=O)C(C)C)c1C
|
C30H36N6O6 576.654000 |
JNIPXVOIXDHQRS-QJXQVQFTSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552717; PubChem:CID163300531
|
Local ready
Direct docking supported
|
|
E3L025558
BDB025558
|
WO2022103411, Example S34
Cc1c(C(=O)O)nnn1[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)C(C)C
|
C29H34N6O6 562.627000 |
AGXHVFFIZNQYNV-AHCIIZGASA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552718; PubChem:CID164607747
|
Local ready
Direct docking supported
|
|
E3L025559
BDB025559
|
WO2022103411, Example S35
Cc1c(C(=O)O)nnn1[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)C(C)C
|
C29H34N6O6 562.627000 |
AGXHVFFIZNQYNV-AGDMDRQQSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552719; PubChem:CID163300512
|
Local ready
Direct docking supported
|
|
E3L025560
BDB025560
|
WO2022103411, Example S36A
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(N)=O)n1nnc2ccccc21
|
C31H34N6O4 554.651000 |
ZZSWGKMAOURNGP-VXGLHPTQSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM552720; PubChem:CID163300749
|
Local ready
Direct docking supported
|