| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L026361
BDB026361
|
US11325921, Example 4
O=C([C@H]1N[C@H]2CC[C@@H]1C(F)(F)C2)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C23H22F8N4OS 554.507000 |
ZXKYRAQRTUGVRY-PJODQICGSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554113; PubChem:CID152730110
|
Local ready
Direct docking supported
|
|
E3L026362
BDB026362
|
US11325921, Example 6
O=C([C@H]1N[C@H]2CC[C@@H]1C[C@@H]2O)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C23H24F6N4O2S 534.526000 |
SGSKCUULBFTJTH-HSHDSVGOSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554116; PubChem:CID151841342
|
Local ready
Direct docking supported
|
|
E3L026363
BDB026363
|
US11325921, Example 7
O=C([C@H]1N[C@H]2CC[C@@H]1[C@@H](O)C2)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C23H24F6N4O2S 534.526000 |
KAHJAGWFBUHJQJ-LPOXYFBYSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554120; PubChem:CID164885564
|
Local ready
Direct docking supported
|
|
E3L026364
BDB026364
|
US11325921, Example 8
O=C1C[C@@H]2CC[C@H]1[C@@H](C(=O)N1CC3(C1)CN(c1c(C(F)(F)F)cnc4sc(CC(F)(F)F)cc14)C3)N2
|
C23H22F6N4O2S 532.510000 |
AVGRXABHJJNRNY-PPHDSNJXSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554121; PubChem:CID149711707
|
Local ready
Direct docking supported
|
|
E3L026365
BDB026365
|
US11325921, Example 10
O=C([C@H]1N[C@H]2C[C@@H]1C[C@H]2F)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C22H21F7N4OS 522.490000 |
UPIPNZWTALWOSN-YVFQKMDQSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554125; PubChem:CID164885565
|
Local ready
Direct docking supported
|
|
E3L026366
BDB026366
|
US11325921, Example 11
C=CCO[C@H]1C[C@H]2C[C@@H]1N[C@@H]2C(=O)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C25H26F6N4O2S 560.564000 |
VJMSEJCFUWKXQR-RPTUDFQQSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554126; PubChem:CID164885566
|
Local ready
Direct docking supported
|
|
E3L026367
BDB026367
|
US11325921, Example 12
C=CCO[C@H]1C[C@H]2C[C@@H]1N[C@H]2C(=O)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C25H26F6N4O2S 560.564000 |
VJMSEJCFUWKXQR-WEZQJLTASA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554127; PubChem:CID164885567
|
Local ready
Direct docking supported
|
|
E3L026368
BDB026368
|
US11325921, Example 13
O=C([C@H]1N[C@H]2C[C@@H]1C[C@@H]2OCc1ccccc1)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C29H28F6N4O2S 610.624000 |
VCGGKAFSZXGDJK-SZOBAZRNSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554128; PubChem:CID164885568
|
Local ready
Direct docking supported
|
|
E3L026369
BDB026369
|
US11325921, Example 14
O=C([C@@H]1N[C@H]2C[C@@H]1C[C@@H]2OCc1ccccc1)N1CC2(C1)CN(c1c(C(F)(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C29H28F6N4O2S 610.624000 |
VCGGKAFSZXGDJK-LMDOGRNLSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554131; PubChem:CID164885569
|
Local ready
Direct docking supported
|
|
E3L026370
BDB026370
|
US11325921, Example 20
N#Cc1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C2)C1
|
C22H22F3N5OS 461.513000 |
ZYADRCWVQPCKIY-QEORTHHSSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554133; PubChem:CID152733024
|
Local ready
Direct docking supported
|
|
E3L026371
BDB026371
|
US11325921, Example 21
N#Cc1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C(=O)[C@@H]3N[C@@H]4CC[C@H]3C4)C2)C1
|
C22H22F3N5OS 461.513000 |
ZYADRCWVQPCKIY-DXCKQFNASA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554134; PubChem:CID164885570
|
Local ready
Direct docking supported
|
|
E3L026372
BDB026372
|
US11325921, Example 22
N#Cc1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C(=O)[C@H]3N[C@H]4C[C@@H]3[C@@H](F)C4)C2)C1
|
C22H21F4N5OS 479.503000 |
NTHBHLVHEBDGDP-YVVXQTMVSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554135; PubChem:CID164885571
|
Local ready
Direct docking supported
|
|
E3L026373
BDB026373
|
US11325921, Example 23
N#Cc1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C(=O)[C@H]3N[C@H]4C[C@@H]3C(F)(F)C4)C2)C1
|
C22H20F5N5OS 497.493000 |
OZMZCHUIKIJUJP-RCBQFDQVSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554136; PubChem:CID164885572
|
Local ready
Direct docking supported
|
|
E3L026374
BDB026374
|
US11325921, Example 25
N#Cc1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C(=O)[C@H]3N[C@@H]4CC(=O)[C@H]3C4)C2)C1
|
C22H20F3N5O2S 475.496000 |
WXYILIFTWPRGQC-QEORTHHSSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554138; PubChem:CID164885573
|
Local ready
Direct docking supported
|
|
E3L026375
BDB026375
|
US11325921, Example 26
O=C([C@H]1N[C@@H]2CC[C@H]1C2)N1CC2(C1)CN(c1c(C(F)F)cnc3sc(CC(F)(F)F)cc13)C2
|
C22H23F5N4OS 486.510000 |
JGYZPBXCLTVSLG-OZVIIMIRSA-N | Q03164 | Menin |
BindingDB, PubChem
BindingDB:BDBM554139; PubChem:CID150676383
|
Local ready
Direct docking supported
|
|
E3L026376
BDB026376
|
3-(2,3-Dihydro-2-oxo-1H-indol-1-yl)-2,6-piperidinedione
O=C1CCC(N2C(=O)Cc3ccccc32)C(=O)N1
|
C13H12N2O3 244.250000 |
MHJRQTYKWMYTQA-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1, Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM557573; PubChem:CID138467349
|
Local ready
Direct docking supported
|
|
E3L026377
BDB026377
|
3-(2-Oxo-4-phenylpyrrolidin-1-yl)piperidine-2,6-dione
O=C1CCC(N2CC(c3ccccc3)CC2=O)C(=O)N1
|
C15H16N2O3 272.304000 |
KBGHRGPBDAUOPL-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1, Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM557620; PubChem:CID138467079
|
Local ready
Direct docking supported
|
|
E3L026378
BDB026378
|
BDBM557621
CN(C)Cc1ccc2c(c1)n(C)c(=O)n2C1CCC(=O)NC1=O
|
C16H20N4O3 316.361000 |
MFCKZYOMPCLDHK-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB, PubChem
BindingDB:BDBM557621; PubChem:CID138491613
|
Local ready
Direct docking supported
|
|
E3L026379
BDB026379
|
BDBM557622
CC(=O)Nc1ccc2c(c1)n(C)c(=O)n2C1CCC(=O)NC1=O
|
C15H16N4O4 316.317000 |
CSZPGTRROXXITP-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB, PubChem
BindingDB:BDBM557622; PubChem:CID138491543
|
Local ready
Direct docking supported
|
|
E3L026380
BDB026380
|
BDBM557623
Cc1ccc2c(c1)n(C)c(=O)n2C1CCC(=O)NC1=O
|
C14H15N3O3 273.292000 |
CYPBVBOKRKWRIH-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB, PubChem
BindingDB:BDBM557623; PubChem:CID138496332
|
Local ready
Direct docking supported
|