| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027661
BDB027661
|
US11458138, Example 62
FC(F)(F)C1(Nc2nc(-c3ccncc3)nc3cnccc23)CCC1
|
C17H14F3N5 345.328000 |
RGIKJUZEMMTILQ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574231; PubChem:CID135368396
|
Local ready
Direct docking supported
|
|
E3L027662
BDB027662
|
US11458138, Example 63
CCC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5 293.374000 |
VCWNZJZLJJLTBZ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574232; PubChem:CID135368317
|
Local ready
Direct docking supported
|
|
E3L027663
BDB027663
|
US11458138, Example 64
FC(F)(F)C1(Nc2nc(-c3ccncc3)nc3cnccc23)CC1
|
C16H12F3N5 331.301000 |
ACTDLFQRJKPKFQ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574233; PubChem:CID135368375
|
Local ready
Direct docking supported
|
|
E3L027664
BDB027664
|
US11458138, Example 65
c1cc(-c2nc(NC3CCCC3)c3ccncc3n2)ccn1
|
C17H17N5 291.358000 |
OCRGFIAWWYJUTP-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574234; PubChem:CID135368704
|
Local ready
Direct docking supported
|
|
E3L027665
BDB027665
|
US11458138, Example 66
CC(C)(CO)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5O 295.346000 |
DCIPFXLSLUFVQA-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574235; PubChem:CID135368371
|
Local ready
Direct docking supported
|
|
E3L027666
BDB027666
|
US11458138, Example 67
COC(=O)C(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C17H14F3N5O2 377.326000 |
QQZBTGFGBCVAAZ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574236; PubChem:CID135368553
|
Local ready
Direct docking supported
|
|
E3L027667
BDB027667
|
US11458138, Example 68b
CCC(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5 279.347000 |
ASUNJYYQHDCQSW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574237; PubChem:CID135368006
|
Local ready
Direct docking supported
|
|
E3L027668
BDB027668
|
US11458138, Example 68a
CC[C@H](C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5 279.347000 |
ASUNJYYQHDCQSW-NSHDSACASA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574238; PubChem:CID135368005
|
Local ready
Direct docking supported
|
|
E3L027669
BDB027669
|
US11458138, Example 69
C#CC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H15N5 289.342000 |
YJJXADLWWIBINT-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574240; PubChem:CID145744574
|
Local ready
Direct docking supported
|
|
E3L027670
BDB027670
|
BDBM574241
C[C@]1(Nc2nc(-c3ccncc3)nc3cnccc23)C[C@@H](O)C1
|
C17H17N5O 307.357000 |
PTPZOJYJIOCLLO-LAUQKZGBSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB
BindingDB:BDBM574241
|
Local ready
Direct docking supported
|
|
E3L027671
BDB027671
|
US11458138, Example 71
CC(C)(O)C(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H21N5O 323.400000 |
IDYBIWQRAAGTKU-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574242; PubChem:CID145744576
|
Local ready
Direct docking supported
|
|
E3L027672
BDB027672
|
US11458138, Example 72
CC(C)(C)CC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C20H25N5 335.455000 |
CGCTZXKRODVTAN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574243; PubChem:CID145744609
|
Local ready
Direct docking supported
|
|
E3L027673
BDB027673
|
US11458138, Example 73
CCC(CC)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5 293.374000 |
AHXOXSJVKFBOCI-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574244; PubChem:CID135368682
|
Local ready
Direct docking supported
|
|
E3L027674
BDB027674
|
US11458138, Example 74
CC(C)(CN1CCOCC1)Nc1nc(-c2ccncc2)nc2cnccc12
|
C20H24N6O 364.453000 |
OORANHYPSLCFDJ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574245; PubChem:CID137350492
|
Local ready
Direct docking supported
|
|
E3L027675
BDB027675
|
US11458138, Example 75
CC(C)(COC(C)(C)C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C20H25N5O 351.454000 |
SOBXNSZXUHKICP-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574246; PubChem:CID135368753
|
Local ready
Direct docking supported
|
|
E3L027676
BDB027676
|
US11458138, Example 76
OCC(CC(F)(F)F)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H14F3N5O 349.316000 |
PHZXWARJCSQYKN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574247; PubChem:CID145744618
|
Local ready
Direct docking supported
|
|
E3L027677
BDB027677
|
US11458138, Example 77
CCCCCNc1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5 293.374000 |
ISWJHQJFIUINEB-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574248; PubChem:CID137350739
|
Local ready
Direct docking supported
|
|
E3L027678
BDB027678
|
US11458138, Example 78
CCC(CO)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5O 295.346000 |
PIYAEDUBKKRBBX-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574249; PubChem:CID135368381
|
Local ready
Direct docking supported
|
|
E3L027679
BDB027679
|
US11458138, Example 79
CC(C)(Cc1c[nH]c2ccccc12)Nc1nc(-c2ccncc2)nc2cnccc12
|
C24H22N6 394.482000 |
VXYPJGHKVFBNME-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574250; PubChem:CID135368499
|
Local ready
Direct docking supported
|
|
E3L027680
BDB027680
|
US11458138, Example 80
CC(C)(Cc1ccc(F)cc1)Nc1nc(-c2ccncc2)nc2cnccc12
|
C22H20FN5 373.435000 |
VVRRRDFLUSHHDP-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574251; PubChem:CID145744551
|
Local ready
Direct docking supported
|