| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L033061
BDB033061
|
US11919855, Name NUCC-0202757
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1ccnc(Cl)n1
|
C17H14ClF3N4O2 398.772000 |
IVSIDFDXZVKFNL-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656403; PubChem:CID166031113
|
Local ready
Direct docking supported
|
|
E3L033062
BDB033062
|
US11919855, Name NUCC-0202758
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1ccc2ccccc2n1
|
C22H18F3N3O2 413.399000 |
NVTMXAGYEHEPLW-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656404; PubChem:CID166031155
|
Local ready
Direct docking supported
|
|
E3L033063
BDB033063
|
BDBM656405
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cscn1
|
C16H14F3N3O2S 369.368000 |
NJUQAPUNIDEWMR-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656405; PubChem:CID45209308
|
Local ready
Direct docking supported
|
|
E3L033064
BDB033064
|
US11919855, Name NUCC-0202760
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1coc2ccccc12
|
C21H17F3N2O3 402.372000 |
LCHIQKKYWSRIDT-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656406; PubChem:CID166031110
|
Local ready
Direct docking supported
|
|
E3L033065
BDB033065
|
US11919855, Name NUCC-0202761
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1ccc2ccccc2c1O
|
C23H19F3N2O3 428.410000 |
FTWOKJQJPULJRK-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656407; PubChem:CID166031093
|
Local ready
Direct docking supported
|
|
E3L033066
BDB033066
|
US11919855, Name NUCC-0202762
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1ccc(Cl)nc1Cl
|
C18H14Cl2F3N3O2 432.229000 |
KFVZEWIPRYYNIC-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656408; PubChem:CID166031123
|
Local ready
Direct docking supported
|
|
E3L033067
BDB033067
|
US11919855, Name NUCC-0202763
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1ccccc1F
|
C19H16F4N2O2 380.341000 |
AQDVYZITYYJCLM-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656409; PubChem:CID166031137
|
Local ready
Direct docking supported
|
|
E3L033068
BDB033068
|
US11919855, Name NUCC-0202764
Cn1nccc1C(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1
|
C17H17F3N4O2 366.343000 |
FPMIUPKOPQVOMB-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656410; PubChem:CID45183640
|
Local ready
Direct docking supported
|
|
E3L033069
BDB033069
|
US11919855, Name NUCC-0202765
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1ccc(Br)c(O)c1
|
C19H16BrF3N2O3 457.246000 |
YLYAPCMZLFPYIS-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656411; PubChem:CID166031109
|
Local ready
Direct docking supported
|
|
E3L033070
BDB033070
|
US11919855, Name NUCC-0202766
O=C1CC(Nc2n[nH]c3ccccc23)CN1Cc1ccccc1C(F)(F)F
|
C19H17F3N4O 374.366000 |
WRZHEHPOMAHNAF-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656412; PubChem:CID166031162
|
Local ready
Direct docking supported
|
|
E3L033071
BDB033071
|
US11919855, Name NUCC-0202792
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(Cl)nc2ccccc12
|
C22H17ClF3N3O2 447.844000 |
QAKLRUKIJCMGDQ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656413; PubChem:CID166031165
|
Local ready
Direct docking supported
|
|
E3L033072
BDB033072
|
US11919855, Name NUCC-0202793
Cc1ccc(N)c(C(=O)NC2CC(=O)N(Cc3ccccc3C(F)(F)F)C2)c1
|
C20H20F3N3O2 391.393000 |
UXSISVAHBGIBKA-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656414; PubChem:CID166031133
|
Local ready
Direct docking supported
|
|
E3L033073
BDB033073
|
US11919855, Name NUCC-0202827
Cc1cccc(O)c1C(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1
|
C20H19F3N2O3 392.377000 |
UCWIMASOZSJPMO-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656416; PubChem:CID166031136
|
Local ready
Direct docking supported
|
|
E3L033074
BDB033074
|
BDBM656417
Cc1c[nH]c(=O)c(C(=O)NC2CC(=O)N(Cc3ccccc3C(F)(F)F)C2)c1
|
C19H18F3N3O3 393.365000 |
FWYASUSTVJCGSZ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656417; PubChem:CID166031169
|
Local ready
Direct docking supported
|
|
E3L033075
BDB033075
|
US11919855, Name NUCC-0202830
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc2ccccc2cc1O
|
C23H19F3N2O3 428.410000 |
BPRJTBCZKCOXNV-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656418; PubChem:CID166031146
|
Local ready
Direct docking supported
|
|
E3L033076
BDB033076
|
US11919855, Name NUCC-0202831
COc1ccc(O)c(C(=O)NC2CC(=O)N(Cc3ccccc3C(F)(F)F)C2)c1
|
C20H19F3N2O4 408.376000 |
UQZBDLNVTZTZAK-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656419; PubChem:CID166031130
|
Local ready
Direct docking supported
|
|
E3L033077
BDB033077
|
US11919855, Name NUCC-0202832
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(F)ccc1O
|
C19H16F4N2O3 396.340000 |
IAUUSRYBILCHIM-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656420; PubChem:CID166031106
|
Local ready
Direct docking supported
|
|
E3L033078
BDB033078
|
US11919855, Name NUCC-0202833
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(Cl)ccc1O
|
C19H16ClF3N2O3 412.795000 |
TYDGICHSDPKZRR-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656421; PubChem:CID166031112
|
Local ready
Direct docking supported
|
|
E3L033079
BDB033079
|
US11919855, Name NUCC-0202834
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(Br)ccc1O
|
C19H16BrF3N2O3 457.246000 |
MWQSDPXZYZFJDX-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656422; PubChem:CID166031163
|
Local ready
Direct docking supported
|
|
E3L033080
BDB033080
|
US11919855, Name NUCC-0202835
Cc1ccc(O)c(S(=O)(=O)NC2CC(=O)N(Cc3ccccc3C(F)(F)F)C2)c1
|
C19H19F3N2O4S 428.432000 |
HOWPDINRTFICPL-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656423; PubChem:CID166031102
|
Local ready
Direct docking supported
|