| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L033101
BDB033101
|
US11919855, Name NUCC-0223627
O=C(NCC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(C(F)(F)F)ccc1O
|
C21H18F6N2O3 460.374000 |
TXVYRVQNBKPNSK-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656445; PubChem:CID167217837
|
Local ready
Direct docking supported
|
|
E3L033102
BDB033102
|
US11919855, Name NUCC-0223628
O=C(N[C@@H]1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
RLKAHEPLYIDLBC-CYBMUJFWSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656446; PubChem:CID166031087
|
Local ready
Direct docking supported
|
|
E3L033103
BDB033103
|
US11919855, Name NUCC-0223629
CC1(C)C(=O)N(Cc2ccccc2C(F)(F)F)CC1NC(=O)c1cc(C(F)(F)F)ccc1O
|
C22H20F6N2O3 474.401000 |
XPDJOAJZSDJIAZ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656447; PubChem:CID166031172
|
Local ready
Direct docking supported
|
|
E3L033104
BDB033104
|
US11919855, Name NUCC-0223632
O=C1CC(Nc2ncnc3ccc(C(F)(F)F)cc23)CN1Cc1ccccc1C(F)(F)F
|
C21H16F6N4O 454.374000 |
KCBFEXPAXYGMJZ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656448; PubChem:CID166031148
|
Local ready
Direct docking supported
|
|
E3L033105
BDB033105
|
US11919855, Name NUCC-0223633
Nc1ccc(C(F)(F)F)cc1C(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1
|
C20H17F6N3O2 445.363000 |
HJNGWLMFSPPJDS-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656449; PubChem:CID166031119
|
Local ready
Direct docking supported
|
|
E3L033106
BDB033106
|
US11919855, Name NUCC-0223634
Nc1ccc(F)cc1C(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1
|
C19H17F4N3O2 395.356000 |
VSONCXPVKKKKJU-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656450; PubChem:CID166031132
|
Local ready
Direct docking supported
|
|
E3L033107
BDB033107
|
US11919855, Name NUCC-0223635
Nc1ccc(Cl)cc1C(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1
|
C19H17ClF3N3O2 411.811000 |
VMITZSYCWRTVJS-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656451; PubChem:CID166031164
|
Local ready
Direct docking supported
|
|
E3L033108
BDB033108
|
US11919855, Name NUCC-0223818
O=C(NC1CCC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(C(F)(F)F)ccc1O
|
C21H18F6N2O3 460.374000 |
BDGXPLPSNOKKGL-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656452; PubChem:CID167217928
|
Local ready
Direct docking supported
|
|
E3L033109
BDB033109
|
US11919855, Name NUCC-0223819
O=C(NC1CCC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(Cl)ccc1O
|
C20H18ClF3N2O3 426.822000 |
JNVTUWXKXKWTHE-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656453; PubChem:CID167217925
|
Local ready
Direct docking supported
|
|
E3L033110
BDB033110
|
US11919855, Name NUCC-0223820
O=C(NC1CCC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1ccc(C(F)(F)F)cc1O
|
C21H18F6N2O3 460.374000 |
HILIUSIVZLVWOV-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656454; PubChem:CID167218229
|
Local ready
Direct docking supported
|
|
E3L033111
BDB033111
|
US11919855, Name NUCC-0223821
O=C(NC1CCN(Cc2ccccc2C(F)(F)F)C1=O)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
RGISNDLAJNEYDD-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656455; PubChem:CID166031104
|
Local ready
Direct docking supported
|
|
E3L033112
BDB033112
|
US11919855, Name NUCC-0223822
O=C(NC1CCN(Cc2ccccc2C(F)(F)F)C1=O)c1ccc(C(F)(F)F)cc1O
|
C20H16F6N2O3 446.347000 |
KPNITGUQICYSBP-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656456; PubChem:CID166031156
|
Local ready
Direct docking supported
|
|
E3L033113
BDB033113
|
US11919855, Name NUCC-0223823
O=C(NC1CCN(Cc2ccccc2C(F)(F)F)C1=O)c1cccc(C(F)(F)F)c1O
|
C20H16F6N2O3 446.347000 |
YLGGMOFHYDVYBY-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656457; PubChem:CID167218434
|
Local ready
Direct docking supported
|
|
E3L033114
BDB033114
|
US11919855, Name NUCC-0223824
O=C(NC1CCN(Cc2ccccc2C(F)(F)F)C1=O)c1cc(Cl)ccc1O
|
C19H16ClF3N2O3 412.795000 |
GICXNOBFMOJDQE-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656458; PubChem:CID166031096
|
Local ready
Direct docking supported
|
|
E3L033115
BDB033115
|
US11919855, Name NUCC-0223825
O=C1C(Nc2ncnc3ccc(C(F)(F)F)cc23)CCN1Cc1ccccc1C(F)(F)F
|
C21H16F6N4O 454.374000 |
ZTGNNYQZDXZSKL-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656459; PubChem:CID167218115
|
Local ready
Direct docking supported
|
|
E3L033116
BDB033116
|
US11919855, Name NUCC-0223826
O=C1CCC(Nc2ncnc3ccc(C(F)(F)F)cc23)CN1Cc1ccccc1C(F)(F)F
|
C22H18F6N4O 468.401000 |
LQKDKCMGPRNFRX-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656460; PubChem:CID167217857
|
Local ready
Direct docking supported
|
|
E3L033117
BDB033117
|
US11919855, Name NUCC-0226232
O=C(NC1CCN(Cc2cccc(C(F)(F)F)c2)C1=O)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
ITNHHNGZNYWNJA-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656461; PubChem:CID167217852
|
Local ready
Direct docking supported
|
|
E3L033118
BDB033118
|
US11919855, Name NUCC-0226233
O=C(NCC1CC(=O)N(Cc2cccc(C(F)(F)F)c2)C1)c1cc(C(F)(F)F)ccc1O
|
C21H18F6N2O3 460.374000 |
XGTGSXQWUZYADE-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656462; PubChem:CID167217836
|
Local ready
Direct docking supported
|
|
E3L033119
BDB033119
|
US11919855, Name NUCC-0226234
O=C(N[C@H]1CC(=O)N(Cc2cccc(C(F)(F)F)c2)C1)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
NCSYVWJIHNIJCY-AWEZNQCLSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656463; PubChem:CID167218108
|
Local ready
Direct docking supported
|
|
E3L033120
BDB033120
|
US11919855, Name NUCC-0226235
O=C(N[C@@H]1CC(=O)N(Cc2cccc(C(F)(F)F)c2)C1)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
NCSYVWJIHNIJCY-CQSZACIVSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656464; PubChem:CID167217856
|
Local ready
Direct docking supported
|