| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L033081
BDB033081
|
US11919855, Name NUCC-0202851
CC(C)(CO)C(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1
|
C17H21F3N2O3 358.360000 |
HRRYTHVWJPKVST-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656425; PubChem:CID166031166
|
Local ready
Direct docking supported
|
|
E3L033082
BDB033082
|
US11919855, Name NUCC-0202852
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(I)ccc1O
|
C19H16F3IN2O3 504.246000 |
JEVVXXCJBTVGDQ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656426; PubChem:CID166031160
|
Local ready
Direct docking supported
|
|
E3L033083
BDB033083
|
US11919855, Name NUCC-0202965
O=C(NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
RLKAHEPLYIDLBC-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656427; PubChem:CID166031117
|
Local ready
Direct docking supported
|
|
E3L033084
BDB033084
|
US11919855, Name NUCC-0202966
Cc1ccc(O)c(C(=O)NC2CC(=O)N(Cc3ccccc3C(=O)O)C2)c1
|
C20H20N2O5 368.389000 |
HSBYKLOIAFGKSU-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656428; PubChem:CID166031153
|
Local ready
Direct docking supported
|
|
E3L033085
BDB033085
|
US11919855, Name NUCC-0202967
COC(=O)c1ccccc1CN1CC(NC(=O)c2cc(C)ccc2O)CC1=O
|
C21H22N2O5 382.416000 |
RBXOKXGNECFJJO-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656429; PubChem:CID166031150
|
Local ready
Direct docking supported
|
|
E3L033086
BDB033086
|
US11919855, Name NUCC-0202968
Cc1ccc(O)c(C(=O)NC2CC(=O)N(Cc3ccccc3C(F)(F)F)C2)n1
|
C19H18F3N3O3 393.365000 |
UJDFGEANMMYBKB-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656430; PubChem:CID166031124
|
Local ready
Direct docking supported
|
|
E3L033087
BDB033087
|
US11919855, Name NUCC-0202969
Cc1ccc(O)c(C(=O)Nc2ccc(=O)n(Cc3ccccc3C(F)(F)F)c2)c1
|
C21H17F3N2O3 402.372000 |
YZYJODSBWNLGQD-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656431; PubChem:CID166031092
|
Local ready
Direct docking supported
|
|
E3L033088
BDB033088
|
US11919855, Name NUCC-0202970
CC(=O)N1CCCC(CN2CC(NC(=O)c3cc(C)ccc3O)CC2=O)C1
|
C20H27N3O4 373.453000 |
LINBRARUOOGKNZ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656432; PubChem:CID166031142
|
Local ready
Direct docking supported
|
|
E3L033089
BDB033089
|
US11919855, Name NUCC-0202971
Cc1ccc(O)c(C(=O)NC2CCC(=O)N(Cc3ccccc3C(F)(F)F)C2)c1
|
C21H21F3N2O3 406.404000 |
WHKDGIASAKFLTF-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656433; PubChem:CID167217926
|
Local ready
Direct docking supported
|
|
E3L033090
BDB033090
|
US11919855, Name NUCC-0202972
COc1ccc(CN2C[C@@H](NC(=O)c3cc(C)ccc3O)CC2=O)c(OC)c1
|
C21H24N2O5 384.432000 |
LYKXSIHCZOWTLO-HNNXBMFYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656434; PubChem:CID166031140
|
Local ready
Direct docking supported
|
|
E3L033091
BDB033091
|
US11919855, Name NUCC-0202973
Cc1ccc(O)c(C(=O)N[C@H]2CC(=O)N(Cc3ccccc3Cl)C2)c1
|
C19H19ClN2O3 358.825000 |
XIRQAFBTBZTVMY-AWEZNQCLSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656435; PubChem:CID166031098
|
Local ready
Direct docking supported
|
|
E3L033092
BDB033092
|
US11919855, Name NUCC-0202974
Cc1ccc(O)c(C(=O)N[C@H]2CC(=O)N(Cc3ccc(C(F)(F)F)cc3)C2)c1
|
C20H19F3N2O3 392.377000 |
KCBOGDXUGIJGLT-HNNXBMFYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656436; PubChem:CID166031095
|
Local ready
Direct docking supported
|
|
E3L033093
BDB033093
|
US11919855, Name NUCC-0202975
Cc1ccc(O)c(C(=O)N[C@H]2CC(=O)N(Cc3ccc(Cl)c(Cl)c3)C2)c1
|
C19H18Cl2N2O3 393.270000 |
SGUWQZMVOBUUAW-ZDUSSCGKSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656437; PubChem:CID166031128
|
Local ready
Direct docking supported
|
|
E3L033094
BDB033094
|
US11919855, Name NUCC-0202976
Cc1ccc(O)c(C(=O)N[C@H]2CC(=O)N(C3CCc4ccccc43)C2)c1
|
C21H22N2O3 350.418000 |
ZYBHVOMLYCYOKM-BUSXIPJBSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656438; PubChem:CID166031144
|
Local ready
Direct docking supported
|
|
E3L033095
BDB033095
|
US11919855, Name NUCC-0202977
Cc1ccc(O)c(C(=O)N[C@@H]2CC(=O)N(Cc3ccc(Cl)c(Cl)c3)C2)c1
|
C19H18Cl2N2O3 393.270000 |
SGUWQZMVOBUUAW-CYBMUJFWSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656439; PubChem:CID166031090
|
Local ready
Direct docking supported
|
|
E3L033096
BDB033096
|
US11919855, Name NUCC-0202978
Cc1ccc(O)c(C(=O)N[C@@H]2CC(=O)N(Cc3ccc(C(F)(F)F)cc3)C2)c1
|
C20H19F3N2O3 392.377000 |
KCBOGDXUGIJGLT-OAHLLOKOSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656440; PubChem:CID166031145
|
Local ready
Direct docking supported
|
|
E3L033097
BDB033097
|
US11919855, Name NUCC-0202979
Cc1ccc(O)c(C(=O)N[C@H]2CC(=O)N(C3C=Cc4ccccc43)C2)c1
|
C21H20N2O3 348.402000 |
JTRWTDMAXYBWEK-BUSXIPJBSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656441; PubChem:CID166031141
|
Local ready
Direct docking supported
|
|
E3L033098
BDB033098
|
US11919855, Name NUCC-0223624
O=C(N[C@H]1CC(=O)N(Cc2ccccc2C(F)(F)F)C1)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
RLKAHEPLYIDLBC-ZDUSSCGKSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656442; PubChem:CID166031100
|
Local ready
Direct docking supported
|
|
E3L033099
BDB033099
|
US11919855, Name NUCC-0223625
O=C(NC1CC(=O)N(Cc2cccc(C(F)(F)F)c2)C1)c1cc(C(F)(F)F)ccc1O
|
C20H16F6N2O3 446.347000 |
NCSYVWJIHNIJCY-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656443; PubChem:CID167217835
|
Local ready
Direct docking supported
|
|
E3L033100
BDB033100
|
US11919855, Name NUCC-0223626
CC1(C)C(=O)N(Cc2ccccc2C(F)(F)F)C[C@H]1NC(=O)c1cc(C(F)(F)F)ccc1O
|
C22H20F6N2O3 474.401000 |
XPDJOAJZSDJIAZ-QGZVFWFLSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM656444; PubChem:CID166031103
|
Local ready
Direct docking supported
|