| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L033821
BDB033821
|
BDBM677291
O=c1c(-c2cnn(-c3ccc(Cl)cc3)c2)c(C(F)(F)F)oc2c(O)c(O)ccc12
|
C19H10ClF3N2O4 422.746000 |
KDPAGFLLKCODNF-UHFFFAOYSA-N | P62877, Q13616 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677291; PubChem:CID164603779
|
Local ready
Direct docking supported
|
|
E3L033822
BDB033822
|
BDBM677292
O=c1c(-c2cnn(-c3ccccc3)c2)c(C(F)(F)F)oc2c(O)c(O)ccc12
|
C19H11F3N2O4 388.301000 |
MCGZAKRKICGDRS-UHFFFAOYSA-N | P62877, Q13616 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677292; PubChem:CID5505129
|
Local ready
Direct docking supported
|
|
E3L033823
BDB033823
|
BDBM677293
O=c1c(-c2cn[nH]c2)c(C(F)(F)F)oc2c(O)c(O)ccc12
|
C13H7F3N2O4 312.203000 |
NVBPLNVPLGFOCB-UHFFFAOYSA-N | P62877, Q13616 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677293; PubChem:CID164603786
|
Local ready
Direct docking supported
|
|
E3L033824
BDB033824
|
BDBM677294
CCCCn1cc(-c2c(C(F)(F)F)oc3c(O)c(O)ccc3c2=O)cn1
|
C17H15F3N2O4 368.311000 |
OCXGVGTXMSRAMP-UHFFFAOYSA-N | P62877, Q13616 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677294; PubChem:CID164603757
|
Local ready
Direct docking supported
|
|
E3L033825
BDB033825
|
BDBM677295
CCCn1cc(-c2c(C(F)(F)F)oc3c(O)c(O)ccc3c2=O)cn1
|
C16H13F3N2O4 354.284000 |
BRPWOFISVRMJAO-UHFFFAOYSA-N | P62877, Q13616 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677295; PubChem:CID164603803
|
Local ready
Direct docking supported
|
|
E3L033826
BDB033826
|
BDBM677296
CCn1cc(-c2c(C(F)(F)F)oc3c(O)c(O)ccc3c2=O)cn1
|
C15H11F3N2O4 340.257000 |
SUEYLZGBGFPNQF-UHFFFAOYSA-N | P62877, Q13616 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677296; PubChem:CID164603702
|
Local ready
Direct docking supported
|
|
E3L033827
BDB033827
|
US20240174649, Example Table9.1
O=c1c(Oc2ccccc2)c(C(F)(F)F)oc2c(O)c(O)c(Br)cc12
|
C16H8BrF3O5 417.133000 |
BLSVREFZBLLMLH-UHFFFAOYSA-N | P62877, Q13619 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677297; PubChem:CID164603804
|
Local ready
Direct docking supported
|
|
E3L033828
BDB033828
|
US20240174649, Example Table9.2
O=c1c(Oc2ccc(Br)cc2)c(C(F)(F)F)oc2c(O)c(O)ccc12
|
C16H8BrF3O5 417.133000 |
GZVGQUWHNKICCD-UHFFFAOYSA-N | P62877, Q13619 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677298; PubChem:CID164603728
|
Local ready
Direct docking supported
|
|
E3L033829
BDB033829
|
US20240174649, Example Table9.3
O=c1c(Oc2cccc(Br)c2)c(C(F)(F)F)oc2c(O)c(O)ccc12
|
C16H8BrF3O5 417.133000 |
JEYHAUZKNGECEU-UHFFFAOYSA-N | P62877, Q13619 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677299; PubChem:CID164603765
|
Local ready
Direct docking supported
|
|
E3L033830
BDB033830
|
US20240174649, Example Table9.4
O=c1c(Oc2ccccc2Br)c(C(F)(F)F)oc2c(O)c(O)ccc12
|
C16H8BrF3O5 417.133000 |
HOPJORAFVCMXME-UHFFFAOYSA-N | P62877, Q13619 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677300; PubChem:CID164603770
|
Local ready
Direct docking supported
|
|
E3L033831
BDB033831
|
US20240174649, Example Table9.5
O=c1c(Oc2ccc(Br)cc2)c(C(F)(F)F)oc2c(O)c(O)c(Br)cc12
|
C16H7Br2F3O5 496.029000 |
VRHYRULMHMRMML-UHFFFAOYSA-N | P62877, Q13619 | E3 ubiquitin-protein ligase RBX1 |
BindingDB, PubChem
BindingDB:BDBM677301; PubChem:CID164603733
|
Local ready
Direct docking supported
|
|
E3L033832
BDB033832
|
BDBM678376
c1cc(-c2nc(N3CCC4(CCNC4)CC3)c3ccncc3n2)ccn1
|
C20H22N6 346.438000 |
PANBXEPRTUWMHA-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678376; PubChem:CID167233241
|
Local ready
Direct docking supported
|
|
E3L033833
BDB033833
|
BDBM678377
CN1CCC2(CCN(c3nc(-c4ccncc4)nc4cnccc34)CC2)C1
|
C21H24N6 360.465000 |
SXOIZZVBAAACIQ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678377; PubChem:CID167233242
|
Local ready
Direct docking supported
|
|
E3L033834
BDB033834
|
BDBM678385
CC(C)(O)CN1CCC2(CCN(c3nc(-c4ccncc4)nc4cnccc34)CC2)C1
|
C24H30N6O 418.545000 |
WEAHURJZQJBTGH-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678385; PubChem:CID167233230
|
Local ready
Direct docking supported
|
|
E3L033835
BDB033835
|
BDBM678390
C[C@@H](O)CN1CCC2(CCN(c3nc(-c4ccncc4)nc4cnccc34)CC2)C1
|
C23H28N6O 404.518000 |
DTVNECWMYCSEBL-QGZVFWFLSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678390; PubChem:CID167233105
|
Local ready
Direct docking supported
|
|
E3L033836
BDB033836
|
BDBM678391
C[C@H](O)CN1CCC2(CCN(c3nc(-c4ccncc4)nc4cnccc34)CC2)C1
|
C23H28N6O 404.518000 |
DTVNECWMYCSEBL-KRWDZBQOSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678391; PubChem:CID167233104
|
Local ready
Direct docking supported
|
|
E3L033837
BDB033837
|
BDBM678399
c1cc(-c2nc(N3CCC4(CCN(CC5COC5)C4)CC3)c3ccncc3n2)ccn1
|
C24H28N6O 416.529000 |
JQAXPHDIJOQPBP-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678399; PubChem:CID167233380
|
Local ready
Direct docking supported
|
|
E3L033838
BDB033838
|
BDBM678403
O[C@@H]1CCC[C@H]1N1CCC2(CCN(c3nc(-c4ccncc4)nc4cnccc34)CC2)C1
|
C25H30N6O 430.556000 |
SAQSMANEGRAMNT-FGZHOGPDSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678403; PubChem:CID167233156
|
Local ready
Direct docking supported
|
|
E3L033839
BDB033839
|
BDBM678404
O[C@H]1CCC[C@@H]1N1CCC2(CCN(c3nc(-c4ccncc4)nc4cnccc34)CC2)C1
|
C25H30N6O 430.556000 |
SAQSMANEGRAMNT-VXKWHMMOSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678404; PubChem:CID167233023
|
Local ready
Direct docking supported
|
|
E3L033840
BDB033840
|
BDBM678422
Cc1n[nH]cc1-c1nc(N2CCC3(CC2)CCN(C2CCCC2)C3)c2ccncc2n1
|
C24H31N7 417.561000 |
UAPFATLGRSUIKX-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM678422; PubChem:CID167233098
|
Local ready
Direct docking supported
|