| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035661
BDB035661
|
BDBM710953
C[C@@H](NC1(C)CCC1)c1cc(Cl)c2c(c1)C(=O)N(c1cccc([C@]3(c4nncn4C)C[C@H](F)C3)c1)C2
|
C28H31ClFN5O 508.041000 |
OHIWAMBAFXDJCL-ROERJRBBSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710953
|
Local ready
Direct docking supported
|
|
E3L035662
BDB035662
|
BDBM710955
CC[C@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@H](c3nncn3C)C3COC3)c1)C2=O
|
C30H34F3N5O2 553.629000 |
KHUHMPCMKSWRNR-UIOOFZCWSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710955; PubChem:CID168262859
|
Local ready
Direct docking supported
|
|
E3L035663
BDB035663
|
BDBM710956
CC[C@@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@H](c3nncn3C)C3COC3)c1)C2=O
|
C30H34F3N5O2 553.629000 |
KHUHMPCMKSWRNR-FTJBHMTQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710956; PubChem:CID168263074
|
Local ready
Direct docking supported
|
|
E3L035664
BDB035664
|
BDBM710957
CC[C@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O
|
C30H34F3N5O2 553.629000 |
KHUHMPCMKSWRNR-IZZNHLLZSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710957; PubChem:CID168262814
|
Local ready
Direct docking supported
|
|
E3L035665
BDB035665
|
BDBM710958
CC[C@@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O
|
C30H34F3N5O2 553.629000 |
KHUHMPCMKSWRNR-CLJLJLNGSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710958; PubChem:CID168262489
|
Local ready
Direct docking supported
|
|
E3L035666
BDB035666
|
BDBM710959
Cn1cnnc1[C@@H](c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1)[C@H]1C[C@@H](F)C1
|
C28H31ClFN5O 508.041000 |
UJEQWHRLDYTMPE-DFIYOIEZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710959
|
Local ready
Direct docking supported
|
|
E3L035667
BDB035667
|
BDBM710960
Cn1cnnc1[C@@H](c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1)[C@H]1C[C@H](F)C1
|
C28H31ClFN5O 508.041000 |
UJEQWHRLDYTMPE-RLSLOFABSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710960
|
Local ready
Direct docking supported
|
|
E3L035668
BDB035668
|
BDBM710961
Cn1cnnc1[C@H](c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1)[C@H]1C[C@@H](F)C1
|
C28H31ClFN5O 508.041000 |
UJEQWHRLDYTMPE-OHUGHZGNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710961
|
Local ready
Direct docking supported
|
|
E3L035669
BDB035669
|
BDBM710962
Cn1cnnc1[C@H](c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1)[C@H]1C[C@H](F)C1
|
C28H31ClFN5O 508.041000 |
UJEQWHRLDYTMPE-UMEGOILYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710962
|
Local ready
Direct docking supported
|
|
E3L035670
BDB035670
|
BDBM710963
Cn1cnnc1[C@](F)(c1ccccc1)c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1
|
C30H29ClFN5O 530.047000 |
YPZMDRYLHICQAT-PMERELPUSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710963; PubChem:CID168262740
|
Local ready
Direct docking supported
|
|
E3L035671
BDB035671
|
BDBM710964
Cn1cnnc1[C@@](F)(c1ccccc1)c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1
|
C30H29ClFN5O 530.047000 |
YPZMDRYLHICQAT-SSEXGKCCSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710964; PubChem:CID168263060
|
Local ready
Direct docking supported
|
|
E3L035672
BDB035672
|
BDBM710965
CS[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H32F3N5OS 555.670000 |
AFQZLRQRMXCEMZ-BFZJZIARSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710965
|
Local ready
Direct docking supported
|
|
E3L035673
BDB035673
|
BDBM710966
CS[C@H]1C[C@@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H32F3N5OS 555.670000 |
AFQZLRQRMXCEMZ-XJTLEKEGSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710966
|
Local ready
Direct docking supported
|
|
E3L035674
BDB035674
|
BDBM710967
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](S(C)(=O)=O)C1
|
C29H32F3N5O3S 587.668000 |
UPLFALGKXTZLSH-BFZJZIARSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710967
|
Local ready
Direct docking supported
|
|
E3L035675
BDB035675
|
BDBM710968
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](S(C)(=O)=O)C1
|
C29H32F3N5O3S 587.668000 |
UPLFALGKXTZLSH-XJTLEKEGSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710968
|
Local ready
Direct docking supported
|
|
E3L035676
BDB035676
|
BDBM710969
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(C(N)=O)cc4C(F)(F)F)C3=O)c2)CCC1
|
C23H20F3N5O2 455.440000 |
LMZWLWNPSGVPBB-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710969; PubChem:CID168262652
|
Local ready
Direct docking supported
|
|
E3L035677
BDB035677
|
BDBM710970
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(C(=O)NC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CS(=O)(=O)C1
|
C27H26F3N5O4S 573.597000 |
CWDDXFOLUXZGBV-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710970; PubChem:CID168835299
|
Local ready
Direct docking supported
|
|
E3L035678
BDB035678
|
BDBM710971
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(C(=O)NC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CSC1
|
C27H26F3N5O2S 541.599000 |
GJVXJJBBFWSHCE-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710971; PubChem:CID168835252
|
Local ready
Direct docking supported
|
|
E3L035679
BDB035679
|
BDBM710972
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(C(=O)NC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[S+]([O-])C1
|
C27H26F3N5O3S 557.598000 |
FESPQUDYDLXPOA-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710972; PubChem:CID168835307
|
Local ready
Direct docking supported
|
|
E3L035680
BDB035680
|
BDBM710973
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[S+]([O-])C1
|
C27H28F3N5O2S 543.615000 |
JRSWBWSVEXDHPO-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710973; PubChem:CID168262836
|
Local ready
Direct docking supported
|