| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035701
BDB035701
|
BDBM710994
Cn1ccnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1COC1
|
C29H31F3N4O2 524.587000 |
XSHWQHBWWZLBIM-VWLOTQADSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710994; PubChem:CID168262796
|
Local ready
Direct docking supported
|
|
E3L035702
BDB035702
|
BDBM710995
Cn1ccnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1COC1
|
C29H31F3N4O2 524.587000 |
XSHWQHBWWZLBIM-RUZDIDTESA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710995; PubChem:CID168262493
|
Local ready
Direct docking supported
|
|
E3L035703
BDB035703
|
BDBM710996
Cn1cnnc1C(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)[C@H]1C[C@@H](Cl)C1
|
C29H31ClF3N5O 558.048000 |
ZLUFMEFGLIZOAP-WPUZRXDDSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710996
|
Local ready
Direct docking supported
|
|
E3L035704
BDB035704
|
BDBM710997
Cn1cnnc1C(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)[C@H]1C[C@H](Cl)C1
|
C29H31ClF3N5O 558.048000 |
ZLUFMEFGLIZOAP-YYSPQECZSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710997
|
Local ready
Direct docking supported
|
|
E3L035705
BDB035705
|
BDBM710998
Cn1cnnc1C(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)[C@H]1C[C@H](Cl)C1
|
C29H31ClF3N5O 558.048000 |
ZLUFMEFGLIZOAP-YYSPQECZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710998
|
Local ready
Direct docking supported
|
|
E3L035706
BDB035706
|
BDBM710999
Cn1cnnc1C(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)[C@H]1C[C@@H](Cl)C1
|
C29H31ClF3N5O 558.048000 |
ZLUFMEFGLIZOAP-WPUZRXDDSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710999
|
Local ready
Direct docking supported
|
|
E3L035707
BDB035707
|
BDBM711000
CC[C@H](c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1)c1nncn1C
|
C26H30ClN5O 464.013000 |
KHNQXHOQZWQJSH-HXUWFJFHSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711000; PubChem:CID168262996
|
Local ready
Direct docking supported
|
|
E3L035708
BDB035708
|
BDBM711001
CC[C@@H](c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1)c1nncn1C
|
C26H30ClN5O 464.013000 |
KHNQXHOQZWQJSH-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711001; PubChem:CID168263068
|
Local ready
Direct docking supported
|
|
E3L035709
BDB035709
|
BDBM711002
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc([C@H](N)C(C)(C)C)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H32F3N5O2 527.591000 |
RGCNFAMRCLHNFW-UHORWHLBSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711002
|
Local ready
Direct docking supported
|
|
E3L035710
BDB035710
|
BDBM711003
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc([C@@H](N)C(C)(C)C)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H32F3N5O2 527.591000 |
RGCNFAMRCLHNFW-AUZMWRNASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711003
|
Local ready
Direct docking supported
|
|
E3L035711
BDB035711
|
BDBM711004
Cn1cnnc1C(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)[C@H]1C[C@@H](CC#N)C1
|
C31H33F3N6O 562.640000 |
VCIZTTBXGHPRNG-MZEYTRHTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711004
|
Local ready
Direct docking supported
|
|
E3L035712
BDB035712
|
BDBM711007
Cn1cnnc1C(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)[C@H]1C[C@@H](CC#N)C1
|
C31H33F3N6O 562.640000 |
VCIZTTBXGHPRNG-MZEYTRHTSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711007
|
Local ready
Direct docking supported
|
|
E3L035713
BDB035713
|
BDBM711008
CO[C@H]1C[C@](O)(C(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)c2nncn2C)C1
|
C30H34F3N5O3 569.628000 |
GKFLWUHMWHBAHM-CTWFWQLESA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711008
|
Local ready
Direct docking supported
|
|
E3L035714
BDB035714
|
BDBM711009
CO[C@H]1C[C@](O)(C(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)c2nncn2C)C1
|
C30H34F3N5O3 569.628000 |
GKFLWUHMWHBAHM-CTWFWQLESA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711009
|
Local ready
Direct docking supported
|
|
E3L035715
BDB035715
|
BDBM711010
CO[C@H]1C[C@@](O)(C(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)c2nncn2C)C1
|
C30H34F3N5O3 569.628000 |
GKFLWUHMWHBAHM-NDIVOCGGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711010
|
Local ready
Direct docking supported
|
|
E3L035716
BDB035716
|
BDBM711011
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](OCF)C1
|
C29H31F4N5O2 557.592000 |
FUKNUNMDYLHWDX-XJTLEKEGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711011
|
Local ready
Direct docking supported
|
|
E3L035717
BDB035717
|
BDBM711012
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](OCF)C1
|
C29H31F4N5O2 557.592000 |
FUKNUNMDYLHWDX-BFZJZIARSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711012
|
Local ready
Direct docking supported
|
|
E3L035718
BDB035718
|
BDBM711013
[2H]C([2H])([2H])O[C@H]1C[C@@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H32F3N5O2 542.620305 |
GXSZEJJGRAAVEG-OIMPTJMVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711013
|
Local ready
Direct docking supported
|
|
E3L035719
BDB035719
|
BDBM711014
[2H]C([2H])([2H])O[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H32F3N5O2 542.620305 |
GXSZEJJGRAAVEG-PFGJXIGJSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711014
|
Local ready
Direct docking supported
|
|
E3L035720
BDB035720
|
BDBM711015
CC[C@H]1C[C@@](c2cccc(N3Cc4c(Cl)cc(CNC5(C)CCC5)cc4C3=O)c2)(c2nncn2C)C1
|
C29H34ClN5O 504.078000 |
GOQVUNGLXCWJNX-CGSFZAOMSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711015
|
Local ready
Direct docking supported
|