| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035681
BDB035681
|
BDBM710974
Cc1cc([C@H](c2nncn2C)C2COC2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C29H32F3N5O2 539.602000 |
CMAXDTMUGBPRLP-VWLOTQADSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710974; PubChem:CID168262734
|
Local ready
Direct docking supported
|
|
E3L035682
BDB035682
|
BDBM710975
Cc1cc([C@@H](c2nncn2C)C2COC2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C29H32F3N5O2 539.602000 |
CMAXDTMUGBPRLP-RUZDIDTESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710975; PubChem:CID168262498
|
Local ready
Direct docking supported
|
|
E3L035683
BDB035683
|
BDBM710976
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](OC(F)F)C1
|
C29H30F5N5O2 575.582000 |
BLSPNFYOEQQKRX-ANXHRGMGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710976
|
Local ready
Direct docking supported
|
|
E3L035684
BDB035684
|
BDBM710977
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](OC(F)F)C1
|
C29H30F5N5O2 575.582000 |
BLSPNFYOEQQKRX-JWZXCJSOSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710977
|
Local ready
Direct docking supported
|
|
E3L035685
BDB035685
|
BDBM710978
CCNc1cc([C@]2(c3nncn3C)C[C@H](C)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1F
|
C31H36F4N6O 584.662000 |
MHTASDRPMCOWMW-KTJIFUHRSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710978
|
Local ready
Direct docking supported
|
|
E3L035686
BDB035686
|
BDBM710979
CCNc1cc([C@]2(c3nncn3C)C[C@@H](C)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1F
|
C31H36F4N6O 584.662000 |
MHTASDRPMCOWMW-GGCACFJLSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710979
|
Local ready
Direct docking supported
|
|
E3L035687
BDB035687
|
BDBM710980
COc1cc([C@H](c2nncn2C)C2COC2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C29H32F3N5O3 555.601000 |
NGHLDGQMLPKNQH-VWLOTQADSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710980; PubChem:CID168263108
|
Local ready
Direct docking supported
|
|
E3L035688
BDB035688
|
BDBM710981
COc1cc([C@@H](c2nncn2C)C2COC2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C29H32F3N5O3 555.601000 |
NGHLDGQMLPKNQH-RUZDIDTESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710981; PubChem:CID168262607
|
Local ready
Direct docking supported
|
|
E3L035689
BDB035689
|
BDBM710982
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@]2(CCCO2)C1
|
C31H34F3N5O2 565.640000 |
ZLTJYNGNTXUNQF-WXUXXXNLSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710982
|
Local ready
Direct docking supported
|
|
E3L035690
BDB035690
|
BDBM710983
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@]2(CCCO2)C1
|
C31H34F3N5O2 565.640000 |
ZLTJYNGNTXUNQF-RNPORBBMSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710983
|
Local ready
Direct docking supported
|
|
E3L035691
BDB035691
|
BDBM710984
Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC1
|
C28H30F3N5O 509.576000 |
HLOUKEPLQBQTTQ-XMMPIXPASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710984; PubChem:CID168262713
|
Local ready
Direct docking supported
|
|
E3L035692
BDB035692
|
BDBM710985
Cn1cnnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC1
|
C28H30F3N5O 509.576000 |
HLOUKEPLQBQTTQ-DEOSSOPVSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710985; PubChem:CID168262828
|
Local ready
Direct docking supported
|
|
E3L035693
BDB035693
|
BDBM710986
Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)n1ccnc1
|
C28H28F3N7O 535.574000 |
JYDHEASSVLQLTL-XMMPIXPASA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710986; PubChem:CID168262452
|
Local ready
Direct docking supported
|
|
E3L035694
BDB035694
|
BDBM710987
Cn1cnnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)n1ccnc1
|
C28H28F3N7O 535.574000 |
JYDHEASSVLQLTL-DEOSSOPVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710987; PubChem:CID168263027
|
Local ready
Direct docking supported
|
|
E3L035695
BDB035695
|
BDBM710988
CC(=O)[C@H]1C[C@@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H32F3N5O2 551.613000 |
GKYIMGQLHMZWQQ-VTNQZFKNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710988
|
Local ready
Direct docking supported
|
|
E3L035696
BDB035696
|
BDBM710989
CC(=O)[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H32F3N5O2 551.613000 |
GKYIMGQLHMZWQQ-BXJXBJKFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710989
|
Local ready
Direct docking supported
|
|
E3L035697
BDB035697
|
BDBM710990
Cn1nnnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1COC1
|
C27H29F3N6O2 526.563000 |
PQOZSBAPVRIRPG-QHCPKHFHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710990; PubChem:CID168835248
|
Local ready
Direct docking supported
|
|
E3L035698
BDB035698
|
BDBM710991
Cn1nnnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1COC1
|
C27H29F3N6O2 526.563000 |
PQOZSBAPVRIRPG-HSZRJFAPSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710991; PubChem:CID168835223
|
Local ready
Direct docking supported
|
|
E3L035699
BDB035699
|
BDBM710992
Cn1nnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](OC(F)(F)F)C1
|
C28H28F6N6O2 594.560000 |
MWELGVLXXIZJCE-VLZXCDOPSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710992
|
Local ready
Direct docking supported
|
|
E3L035700
BDB035700
|
BDBM710993
Cn1nnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](OC(F)(F)F)C1
|
C28H28F6N6O2 594.560000 |
MWELGVLXXIZJCE-KQODVJPSSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710993
|
Local ready
Direct docking supported
|