| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035741
BDB035741
|
BDBM711036
Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC(CC(F)(F)F)C1
|
C31H33F6N5O 605.627000 |
VUHJPUTWXDGMAY-MPZYELNSSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711036
|
Local ready
Direct docking supported
|
|
E3L035742
BDB035742
|
BDBM711037
Cn1cnnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC(OC(F)(F)F)C1
|
C30H31F6N5O2 607.599000 |
YSIGPHXBCCDXSF-BPOAOHNVSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711037
|
Local ready
Direct docking supported
|
|
E3L035743
BDB035743
|
BDBM711038
Cn1cnnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC(OC(F)(F)F)C1
|
C30H31F6N5O2 607.599000 |
YSIGPHXBCCDXSF-BPOAOHNVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711038
|
Local ready
Direct docking supported
|
|
E3L035744
BDB035744
|
BDBM711039
Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC(OC(F)(F)F)C1
|
C30H31F6N5O2 607.599000 |
YSIGPHXBCCDXSF-AJPKXHFHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711039
|
Local ready
Direct docking supported
|
|
E3L035745
BDB035745
|
BDBM711040
CC(=O)N(C)[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)c1nncn1C
|
C28H31F3N6O2 540.590000 |
QGKULZNNOSWVPX-XMMPIXPASA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM711040; PubChem:CID168835332
|
Local ready
Direct docking supported
|
|
E3L035746
BDB035746
|
BDBM711041
CC(=O)N(C)[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)c1nncn1C
|
C28H31F3N6O2 540.590000 |
QGKULZNNOSWVPX-DEOSSOPVSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711041; PubChem:CID168262695
|
Local ready
Direct docking supported
|
|
E3L035747
BDB035747
|
BDBM711042
CC(=O)N1CC([C@H](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)c2nncn2C)C1
|
C30H33F3N6O2 566.628000 |
HXEBFWWXKFPHNV-SANMLTNESA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711042; PubChem:CID168262798
|
Local ready
Direct docking supported
|
|
E3L035748
BDB035748
|
BDBM711043
CC(=O)N1CC([C@@H](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)c2nncn2C)C1
|
C30H33F3N6O2 566.628000 |
HXEBFWWXKFPHNV-AREMUKBSSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711043; PubChem:CID168835227
|
Local ready
Direct docking supported
|
|
E3L035749
BDB035749
|
BDBM711044
Cn1cnnc1[C@](F)(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1(F)COC1
|
C28H28F5N5O2 561.555000 |
MAJYBVPWCZGHPD-HHHXNRCGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711044; PubChem:CID168263109
|
Local ready
Direct docking supported
|
|
E3L035750
BDB035750
|
BDBM711045
Cn1cnnc1[C@@](F)(c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1(F)COC1
|
C28H28F5N5O2 561.555000 |
MAJYBVPWCZGHPD-MHZLTWQESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711045; PubChem:CID168262658
|
Local ready
Direct docking supported
|
|
E3L035751
BDB035751
|
BDBM711046
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@](O)(C(F)F)C1
|
C29H30F5N5O2 575.582000 |
RTQUACIYEWFZOH-HNRBIFIRSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711046
|
Local ready
Direct docking supported
|
|
E3L035752
BDB035752
|
BDBM711047
C[C@@H](NC1(C)CCC1)c1cc2c(c(C(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O
|
C29H33F2N5O2 521.612000 |
ZEYDBVDHJVJKOI-CRICUBBOSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711047; PubChem:CID168263031
|
Local ready
Direct docking supported
|
|
E3L035753
BDB035753
|
BDBM711048
C[C@H](NC1(C)CCC1)c1cc2c(c(C(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O
|
C29H33F2N5O2 521.612000 |
ZEYDBVDHJVJKOI-SSOJOUAXSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM711048; PubChem:CID168263048
|
Local ready
Direct docking supported
|
|
E3L035754
BDB035754
|
BDBM711049
Cn1cnnc1[C@@H](c1cc(Cl)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1COC1
|
C28H29ClF3N5O2 560.020000 |
FSCGAETYKPUJTF-DEOSSOPVSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM711049; PubChem:CID168262912
|
Local ready
Direct docking supported
|
|
E3L035755
BDB035755
|
BDBM711050
Cn1cnnc1[C@H](c1cc(Cl)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1COC1
|
C28H29ClF3N5O2 560.020000 |
FSCGAETYKPUJTF-XMMPIXPASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711050; PubChem:CID168262797
|
Local ready
Direct docking supported
|
|
E3L035756
BDB035756
|
BDBM711051
Cn1cnnc1[C@@](O)(c1ccccc1)c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1
|
C30H30ClN5O2 528.056000 |
VYXWDWASIGFTDU-SSEXGKCCSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711051; PubChem:CID168835290
|
Local ready
Direct docking supported
|
|
E3L035757
BDB035757
|
BDBM711052
Cn1cnnc1[C@](O)(c1ccccc1)c1cccc(N2Cc3c(Cl)cc(CNC4(C)CCC4)cc3C2=O)c1
|
C30H30ClN5O2 528.056000 |
VYXWDWASIGFTDU-PMERELPUSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711052; PubChem:CID168262849
|
Local ready
Direct docking supported
|
|
E3L035758
BDB035758
|
BDBM711053
C[C@@H](NC1(C)CCC1)c1cc2c(c(C(F)F)c1)CN(c1cccc([C@H](c3nncn3C)C3COC3)c1)C2=O
|
C29H33F2N5O2 521.612000 |
ZEYDBVDHJVJKOI-NSYGIPOTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711053; PubChem:CID168262532
|
Local ready
Direct docking supported
|
|
E3L035759
BDB035759
|
BDBM711054
C[C@H](NC1(C)CCC1)c1cc2c(c(C(F)F)c1)CN(c1cccc([C@H](c3nncn3C)C3COC3)c1)C2=O
|
C29H33F2N5O2 521.612000 |
ZEYDBVDHJVJKOI-GKVSMKOHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM711054; PubChem:CID168262629
|
Local ready
Direct docking supported
|
|
E3L035760
BDB035760
|
BDBM711055
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H30F3N5O2 525.575000 |
MCRPCXDVVXVUKA-GBWRQWNLSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711055
|
Local ready
Direct docking supported
|