| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L036421
BDB036421
|
BDBM730440
O=C1CCC(N2Cc3c(CNC(=O)c4cc(C(F)(F)F)cc(Cl)c4F)cccc3C2=O)C(=O)N1
|
C22H16ClF4N3O4 497.832000 |
KYQWSRIFEGVWAX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730440; PubChem:CID176511255
|
Local ready
Direct docking supported
|
|
E3L036422
BDB036422
|
BDBM730441
O=C1CCC(N2Cc3c(CNC(=O)c4ccc(Cl)cc4F)cccc3C2=O)C(=O)N1
|
C21H17ClFN3O4 429.835000 |
PGDFAEZHYZOCMO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730441; PubChem:CID176511256
|
Local ready
Direct docking supported
|
|
E3L036423
BDB036423
|
BDBM730442
O=C1CCC(N2Cc3c(CNC(=O)c4cc(F)ccc4F)cccc3C2=O)C(=O)N1
|
C21H17F2N3O4 413.380000 |
PIXKCSQMNXHRFF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730442; PubChem:CID176511257
|
Local ready
Direct docking supported
|
|
E3L036424
BDB036424
|
BDBM730443
O=C1CCC(N2Cc3c(CNC(=O)c4cccc5cc[nH]c45)cccc3C2=O)C(=O)N1
|
C23H20N4O4 416.437000 |
TWHVFFQHAAVONG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730443; PubChem:CID176511258
|
Local ready
Direct docking supported
|
|
E3L036425
BDB036425
|
BDBM730444
O=C1CCC(N2Cc3c(CNC(=O)c4cccc5[nH]ccc45)cccc3C2=O)C(=O)N1
|
C23H20N4O4 416.437000 |
LNRNPVXITICEIR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730444; PubChem:CID176511259
|
Local ready
Direct docking supported
|
|
E3L036426
BDB036426
|
BDBM730445
O=C(Cc1ccc(O)cc1)NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C22H21N3O5 407.426000 |
FTYBQTWWGKAGJQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730445; PubChem:CID176511260
|
Local ready
Direct docking supported
|
|
E3L036427
BDB036427
|
BDBM730446
O=C(Cc1ccccc1Br)NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C22H20BrN3O4 470.323000 |
WYQIJGKEOSYOPF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730446; PubChem:CID176511261
|
Local ready
Direct docking supported
|
|
E3L036428
BDB036428
|
BDBM730447
O=C1CCC(N2Cc3c(CNC(=O)c4ccc5nc[nH]c5c4)cccc3C2=O)C(=O)N1
|
C22H19N5O4 417.425000 |
OZSHAAVBBMFQNL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730447; PubChem:CID176511262
|
Local ready
Direct docking supported
|
|
E3L036429
BDB036429
|
BDBM730448
O=C1CCC(N2Cc3c(CNC(=O)c4ccccc4Nc4cccc(C(F)(F)F)c4)cccc3C2=O)C(=O)N1
|
C28H23F3N4O4 536.510000 |
WIBAMMOSNXWEDU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730448; PubChem:CID176511263
|
Local ready
Direct docking supported
|
|
E3L036430
BDB036430
|
BDBM730449
O=C1CCC(N2Cc3c(CNC(=O)c4ccc(-c5ccc(Cl)cc5)o4)cccc3C2=O)C(=O)N1
|
C25H20ClN3O5 477.904000 |
HQDHJMRFVMKLAV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730449; PubChem:CID176511264
|
Local ready
Direct docking supported
|
|
E3L036431
BDB036431
|
BDBM730450
O=C1CCC(N2Cc3c(CNC(=O)c4ccccc4Nc4ccccc4)cccc3C2=O)C(=O)N1
|
C27H24N4O4 468.513000 |
FHLIRPGWSKBPAG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730450; PubChem:CID176511265
|
Local ready
Direct docking supported
|
|
E3L036432
BDB036432
|
BDBM730451
O=C1CCC(N2Cc3c(CNC(=O)c4ccccc4Cl)cccc3C2=O)C(=O)N1
|
C21H18ClN3O4 411.845000 |
FTTPHQXTNXXEES-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM730451; PubChem:CID174550521
|
Local ready
Direct docking supported
|
|
E3L036433
BDB036433
|
US20250122182, Syn. Ex. 101
CCc1ccc(OCCNC(=O)OCC2c3ccccc3C3C=CC=CC32)c(S(=O)(=O)Nc2noc3cc(Cn4cc(CNC(=O)OC)cn4)cc(OC)c23)c1
|
C40H42N6O9S 782.876000 |
DWCUGXMQXKHDSW-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730780; PubChem:CID176511319
|
Local ready
Direct docking supported
|
|
E3L036434
BDB036434
|
US20250122182, Syn. Ex. 102
C=C(F)C(=O)NCc1cnn(Cc2cc(OC)c3c(NS(=O)(=O)c4cc(CC)ccc4OCCNC(=O)OCC4c5ccccc5C5C=CC=CC54)noc3c2)c1
|
C41H41FN6O8S 796.878000 |
DBODAIPANYCWTF-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730781; PubChem:CID176511320
|
Local ready
Direct docking supported
|
|
E3L036435
BDB036435
|
US20250122183, Example 002
CCc1cc(Nc2cc3onc(NS(=O)(=O)c4c(OC)cccc4OC)c3cc2OC)[nH]n1
|
C21H23N5O6S 473.511000 |
GCMPQUAYHRAGPZ-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730782; PubChem:CID176308875
|
Local ready
Direct docking supported
|
|
E3L036436
BDB036436
|
US20250122182, Syn. Ex. 107
C=C(F)C(=O)Nc1ccc(Oc2cc(OC)c3c(NS(=O)(=O)C4=C(OC)C=CC(CC)C4)noc3c2)nc1
|
C25H25FN4O7S 544.561000 |
GQKVSXFCPHAQCN-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730783; PubChem:CID176511321
|
Local ready
Direct docking supported
|
|
E3L036437
BDB036437
|
US20250122183, Example 003
COc1cc2c(NS(=O)(=O)c3c(OC)cccc3OC)noc2cc1Nc1cc[nH]n1
|
C19H19N5O6S 445.457000 |
QJQWOQQSEONHLW-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730784; PubChem:CID176308929
|
Local ready
Direct docking supported
|
|
E3L036438
BDB036438
|
US20250122182, Syn. Ex. 52
C=C(F)C(=O)NCc1cnn(Cc2cc(OC(F)F)c3c(NS(=O)(=O)c4cc(CC)ccc4OC)noc3c2)c1
|
C25H24F3N5O6S 579.557000 |
WDYYDZGQZUYHDU-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730785; PubChem:CID176326558
|
Local ready
Direct docking supported
|
|
E3L036439
BDB036439
|
US20250122182, Syn. Ex. 50
COC(=O)NCc1cnn(Cc2cc(OC(F)F)c3c(NS(=O)(=O)c4c(OC)cccc4OC)noc3c2)c1
|
C23H23F2N5O8S 567.527000 |
HHWGNUUDHYRFNP-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730786; PubChem:CID176326563
|
Local ready
Direct docking supported
|
|
E3L036440
BDB036440
|
US20250122183, Example 004
COc1cc2c(NS(=O)(=O)c3c(OC)cccc3OC)noc2cc1Nc1ccn(C)n1
|
C20H21N5O6S 459.484000 |
GOQGPSRYBRCOHR-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730787; PubChem:CID176308727
|
Local ready
Direct docking supported
|