| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L036441
BDB036441
|
Kat6-IN-1
COc1ccccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12
|
C19H18N4O5S 414.443000 |
RCBWSTJGOASLEO-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730788; PubChem:CID155411211
|
Local ready
Direct docking supported
|
|
E3L036442
BDB036442
|
US20250122182, Syn. Ex. 7
COC(=O)NCc1cnn(Cc2cc(OC)c3c(NS(=O)(=O)c4ccccc4OC)noc3c2)c1
|
C22H23N5O7S 501.521000 |
WBRLXEGDHURSOO-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730789; PubChem:CID176511322
|
Local ready
Direct docking supported
|
|
E3L036443
BDB036443
|
US20250122182, Syn. Ex. 14
C=C(F)C(=O)NCc1cnn(Cc2cc(OC)c3c(NS(=O)(=O)C4=C(OC)C=CC(CC)C4)noc3c2)c1
|
C25H28FN5O6S 545.593000 |
KPBCZMQNOKGTAC-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730790; PubChem:CID176511323
|
Local ready
Direct docking supported
|
|
E3L036444
BDB036444
|
US20250122182, Syn. Ex. 15
CC#CC(=O)NCc1cnn(Cc2cc(OC)c3c(NS(=O)(=O)C4=C(OC)C=CC(CC)C4)noc3c2)c1
|
C26H29N5O6S 539.614000 |
QMRXUJKMYXOLSV-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730791; PubChem:CID176511324
|
Local ready
Direct docking supported
|
|
E3L036445
BDB036445
|
US20250122182, Syn. Ex. 25
COC(=O)NCc1cnn(Cc2cc(OC)c3c(NS(=O)(=O)c4cc5c(cc4OC)CCC5)noc3c2)c1
|
C25H27N5O7S 541.586000 |
FERCTRJWYMXSCB-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730792; PubChem:CID176511325
|
Local ready
Direct docking supported
|
|
E3L036446
BDB036446
|
US20250122183, Example 005
COc1cc2c(NS(=O)(=O)c3cc4c(cc3OC)CCCC4)noc2cc1Nc1cc[nH]n1
|
C22H23N5O5S 469.523000 |
PMIUIWMKYCWCIT-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730793; PubChem:CID176308911
|
Local ready
Direct docking supported
|
|
E3L036447
BDB036447
|
US20250122183, Example 006
COc1cc2c(NS(=O)(=O)c3ccccc3OC)noc2cc1Nc1cc(C)n[nH]1
|
C19H19N5O5S 429.458000 |
NWZKOEDRFSVGLU-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730794; PubChem:CID176308920
|
Local ready
Direct docking supported
|
|
E3L036448
BDB036448
|
US20250122183, Example 007
COc1ccc(Cn2nc(C3CC3)cc2Nc2cc3onc(NS(=O)(=O)c4c(OC)cc(-c5cccnc5)cc4OC)c3cc2OC)cc1
|
C35H34N6O7S 682.759000 |
ZYVLPZNPYZYZES-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730795; PubChem:CID176308657
|
Local ready
Direct docking supported
|
|
E3L036449
BDB036449
|
US20250122183, Example 008
COc1cc2c(NS(=O)(=O)c3c(OC)cc(-c4ncco4)cc3OC)noc2cc1Nc1cc(C2CC2)n[nH]1
|
C25H24N6O7S 552.569000 |
HEALUYMIMKNEIO-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730796; PubChem:CID176308753
|
Local ready
Direct docking supported
|
|
E3L036450
BDB036450
|
US20250122183, Example 009
COc1ccccc1S(=O)(=O)Nc1noc2cc(Nc3cc[nH]n3)cc(OC)c12
|
C18H17N5O5S 415.431000 |
RZWDESKLSMUQIH-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730797; PubChem:CID176511326
|
Local ready
Direct docking supported
|
|
E3L036451
BDB036451
|
US20250122183, Example 010
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(NC3CCC3)cc(OC)c12
|
C20H23N3O6S 433.486000 |
WPDCCOITGUABOH-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730798; PubChem:CID176511327
|
Local ready
Direct docking supported
|
|
E3L036452
BDB036452
|
US20250122183, Example 011
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(NC3COC3)cc(OC)c12
|
C19H21N3O7S 435.458000 |
ZNWDMCPPKYZTOK-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730799; PubChem:CID176511328
|
Local ready
Direct docking supported
|
|
E3L036453
BDB036453
|
US20250122183, Example 012
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(NC3CCCC3)cc(OC)c12
|
C21H25N3O6S 447.513000 |
FNLVDYCBRYMHSN-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730800; PubChem:CID176511329
|
Local ready
Direct docking supported
|
|
E3L036454
BDB036454
|
US20250122183, Example 013
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(N[C@@H]3CCOC3)cc(OC)c12
|
C20H23N3O7S 449.485000 |
YRDHIRDCQKBRJF-GFCCVEGCSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730801; PubChem:CID176511330
|
Local ready
Direct docking supported
|
|
E3L036455
BDB036455
|
US20250122183, Example 014
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(N[C@H]3CCOC3)cc(OC)c12
|
C20H23N3O7S 449.485000 |
YRDHIRDCQKBRJF-LBPRGKRZSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730802; PubChem:CID176511331
|
Local ready
Direct docking supported
|
|
E3L036456
BDB036456
|
US20250122183, Example 015
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Nc3ncc[nH]3)cc(OC)c12
|
C19H19N5O6S 445.457000 |
ARNPCPMHTAVARM-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730803; PubChem:CID176511332
|
Local ready
Direct docking supported
|
|
E3L036457
BDB036457
|
US20250122183, Example 016
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Nc3ccon3)cc(OC)c12
|
C19H18N4O7S 446.441000 |
CVMBDMYUBCYNAB-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730804; PubChem:CID176511333
|
Local ready
Direct docking supported
|
|
E3L036458
BDB036458
|
US20250122183, Example 017
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Nc3ncco3)cc(OC)c12
|
C19H18N4O7S 446.441000 |
MCLSYFYVBCMDHT-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730805; PubChem:CID176511334
|
Local ready
Direct docking supported
|
|
E3L036459
BDB036459
|
US20250122183, Example 018
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Nc3ccccn3)cc(OC)c12
|
C21H20N4O6S 456.480000 |
IWNZJJWQUOJKGP-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730806; PubChem:CID176511335
|
Local ready
Direct docking supported
|
|
E3L036460
BDB036460
|
US20250122183, Example 019
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Nc3cccnn3)cc(OC)c12
|
C20H19N5O6S 457.468000 |
ZCZGQNZYPLSGQU-UHFFFAOYSA-N | Q6IE81, Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM730807; PubChem:CID176511336
|
Local ready
Direct docking supported
|