| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041321
BDB041321
|
US12421228, Example 36
Cc1ncccc1-c1cnc(NCc2c(F)ccc3c2CCO3)c2c[nH]c(=O)cc12
|
C23H19FN4O2 402.429000 |
IPQBFHGCDLEDCB-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773564; PubChem:CID155239980
|
Local ready
Direct docking supported
|
|
E3L041322
BDB041322
|
US12421228, Example 37
O=c1cc2c(-c3ccc(CN4CCCC4)cc3)cnc(NCc3c(F)ccc4c3CCO4)c2c[nH]1
|
C28H27FN4O2 470.548000 |
CALVBJZVZDLHNR-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773565; PubChem:CID155239979
|
Local ready
Direct docking supported
|
|
E3L041323
BDB041323
|
US12421228, Example 38
CN(C)Cc1ccc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3c[nH]c(=O)cc23)cc1
|
C26H25FN4O2 444.510000 |
QLAMZUGBQPAAHB-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773566; PubChem:CID155239978
|
Local ready
Direct docking supported
|
|
E3L041324
BDB041324
|
US12421228, Example 39
Cn1nncc1-c1cnc(NCc2c(F)ccc3c2CCO3)c2c[nH]c(=O)cc12
|
C20H17FN6O2 392.394000 |
GOHAJPYGQFRMAC-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773567; PubChem:CID155240003
|
Local ready
Direct docking supported
|
|
E3L041325
BDB041325
|
US12421228, Example 40
Cc1cc(S(C)(=O)=O)ccc1-c1cnc(NCc2c(F)ccc3c2CCO3)c2c[nH]c(=O)cc12
|
C25H22FN3O4S 479.533000 |
XINQKOUMKUTAMI-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773568; PubChem:CID155240004
|
Local ready
Direct docking supported
|
|
E3L041326
BDB041326
|
US12421228, Example 42
CCOc1cc2c(-c3cc(C)nn3C)cnc(NCc3c(F)ccc4c3CCO4)c2cn1
|
C24H24FN5O2 433.487000 |
MXILMLDOSFJCLN-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773569; PubChem:CID155235326
|
Local ready
Direct docking supported
|
|
E3L041327
BDB041327
|
US12421228, Example 43
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3cnc(OC(C)C)cc23)n(C)n1
|
C25H26FN5O2 447.514000 |
WGGATYCEFNLSCB-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773570; PubChem:CID155240334
|
Local ready
Direct docking supported
|
|
E3L041328
BDB041328
|
US12421228, Example 44
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3cnc(OCCN(C)C)cc23)n(C)n1
|
C26H29FN6O2 476.556000 |
CVMHGVSLEFSBJR-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773571; PubChem:CID155240332
|
Local ready
Direct docking supported
|
|
E3L041329
BDB041329
|
US12421228, Example 45
COCCOc1cc2c(-c3cc(C)nn3C)cnc(NCc3c(F)ccc4c3CCO4)c2cn1
|
C25H26FN5O3 463.513000 |
VUFGPURXIWLHKR-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773572; PubChem:CID155240338
|
Local ready
Direct docking supported
|
|
E3L041330
BDB041330
|
US12421228, Example 46
CN(C)CCn1nccc1C1CN=C(NCc2c(F)ccc3c2CCO3)c2c[nH]c(=O)cc21
|
C24H27FN6O2 450.518000 |
WFNUZROMXSDOLF-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773573; PubChem:CID177859236
|
Local ready
Direct docking supported
|
|
E3L041331
BDB041331
|
US12421228, Example 47
Cn1nc(C(N)=O)cc1-c1cnc(NCc2c(F)ccc3c2CCO3)c2c[nH]c(=O)cc12
|
C22H19FN6O3 434.431000 |
CPZNQKRBLFEJRP-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773574; PubChem:CID155240001
|
Local ready
Direct docking supported
|
|
E3L041332
BDB041332
|
US12421228, Example 48
Cn1nc(C#N)cc1-c1cnc(NCc2c(F)ccc3c2CCO3)c2c[nH]c(=O)cc12
|
C22H17FN6O2 416.416000 |
SOFHDBMIHRYXOT-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773575; PubChem:CID155235113
|
Local ready
Direct docking supported
|
|
E3L041333
BDB041333
|
US12421228, Example 49
Cc1cc2c(-c3cc(C)nn3C)cnc(NCc3c(F)ccc4c3CCO4)c2cn1
|
C23H22FN5O 403.461000 |
BXRKNZOABLFJOJ-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773576; PubChem:CID155240342
|
Local ready
Direct docking supported
|
|
E3L041334
BDB041334
|
US12421228, Example 50
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3cnc(N)cc23)n(C)n1
|
C22H21FN6O 404.449000 |
AEUBSYUZHIQZFX-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773577; PubChem:CID155235190
|
Local ready
Direct docking supported
|
|
E3L041335
BDB041335
|
US12421228, Example 51
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3cccnc23)n(C)n1
|
C22H20FN5O 389.434000 |
VAIROHXUNARCFZ-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773578; PubChem:CID155235215
|
Local ready
Direct docking supported
|
|
E3L041336
BDB041336
|
US12421228, Example 52
COc1ccc2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cc(C)nn3C)c2n1
|
C23H22FN5O2 419.460000 |
ZZFJVLJNQYFWIY-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773579; PubChem:CID155239985
|
Local ready
Direct docking supported
|
|
E3L041337
BDB041337
|
US12421228, Example 53
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3ccc(=O)[nH]c23)n(C)n1
|
C22H20FN5O2 405.433000 |
NQQJAGWANXYSIR-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773580; PubChem:CID155239986
|
Local ready
Direct docking supported
|
|
E3L041338
BDB041338
|
US12421228, Example 54
COc1nccc2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cc(C)nn3C)c12
|
C23H22FN5O2 419.460000 |
DWINFAJYDPAFMF-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773581; PubChem:CID155235222
|
Local ready
Direct docking supported
|
|
E3L041339
BDB041339
|
US12421228, Example 55
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3cc[nH]c(=O)c23)n(C)n1
|
C22H20FN5O2 405.433000 |
KDNVZYOCMAUIRJ-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773582; PubChem:CID155235519
|
Local ready
Direct docking supported
|
|
E3L041340
BDB041340
|
US12421228, Example 56
Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)c3ccncc23)n(C)n1
|
C22H20FN5O 389.434000 |
CYZMQQCWQVCHNO-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM773583; PubChem:CID155235195
|
Local ready
Direct docking supported
|