| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L043461
BDB043461
|
BDBM50007642
CC[C@@H](CN(c1ccccc1F)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H31Cl2FN2O6S 649.568000 |
SXZRYPDVACMWHO-JTOAADIHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007642; PubChem:CID90342080
|
Local ready
Direct docking supported
|
|
E3L043462
BDB043462
|
BDBM50007643
CC[C@@H](CN(c1ccc(F)cc1)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H31Cl2FN2O6S 649.568000 |
SBXLFERAJBPODD-JYLYBSOGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007643; PubChem:CID90342208
|
Local ready
Direct docking supported
|
|
E3L043463
BDB043463
|
BDBM50007644
CC[C@@H](CN(c1ccc(F)cc1F)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H30Cl2F2N2O6S 667.558000 |
JKRHWWVFXHVICO-JTOAADIHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007644; PubChem:CID89490890
|
Local ready
Direct docking supported
|
|
E3L043464
BDB043464
|
BDBM50007645
CC[C@@H](CN(c1ccccc1F)S(=O)(=O)C(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H33Cl2FN2O6S 651.584000 |
PAIRTUDVJJOKQA-JYLYBSOGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007645; PubChem:CID90347748
|
Local ready
Direct docking supported
|
|
E3L043465
BDB043465
|
BDBM50007646
CC[C@@H](CN(c1ccccc1F)S(C)(=O)=O)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H29Cl2FN2O6S 623.530000 |
TVELMQBTPDLJJH-MNJVUJALSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007646; PubChem:CID90347747
|
Local ready
Direct docking supported
|
|
E3L043466
BDB043466
|
BDBM50007647
CC[C@@H](CS(=O)(=O)CC)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C24H27Cl2NO6S 528.454000 |
DLMBWZNPJUBFJQ-KKSHJYNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007647; PubChem:CID89478524
|
Local ready
Direct docking supported
|
|
E3L043467
BDB043467
|
BDBM50007648
CC[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C25H29Cl2NO6S 542.481000 |
CFPKREAUMGRDCF-XWVZOOPGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007648; PubChem:CID89478498
|
Local ready
Direct docking supported
|
|
E3L043468
BDB043468
|
BDBM50007649
CC[C@@H](CS(=O)(=O)CC(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H33Cl2NO6S 570.535000 |
VRPHYLSRSHQGSA-WREZULKGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007649; PubChem:CID89490809
|
Local ready
Direct docking supported
|
|
E3L043469
BDB043469
|
BDBM50007650
CC[C@@H](CS(=O)(=O)C1CCCC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H31Cl2NO6S 568.519000 |
HEBMMSWPWCLALG-BKRIMNEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007650; PubChem:CID89490787
|
Local ready
Direct docking supported
|
|
E3L043470
BDB043470
|
BDBM50007651
CC[C@@H](CS(=O)(=O)c1ccccc1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H27Cl2NO6S 576.498000 |
OYIOIAVUIFVMQO-BMJBQGFASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007651; PubChem:CID89478729
|
Local ready
Direct docking supported
|
|
E3L043471
BDB043471
|
BDBM50007652
CC[C@@H](CS(=O)(=O)N(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C24H28Cl2N2O6S 543.469000 |
NAMAMZYCRXXSRK-KKSHJYNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007652; PubChem:CID86730799
|
Local ready
Direct docking supported
|
|
E3L043472
BDB043472
|
BDBM50007653
CC[C@@H](CS(=O)(=O)C1COC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C25H27Cl2NO7S 556.464000 |
RJLKDGSMELXEIB-IVGWJTKZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007653; PubChem:CID89490693
|
Local ready
Direct docking supported
|
|
E3L043473
BDB043473
|
BDBM50007654
C[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C25H29Cl2NO6S 542.481000 |
BDCZVHOYIUXHLE-APQCTARYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007654; PubChem:CID86730805
|
Local ready
Direct docking supported
|
|
E3L043474
BDB043474
|
BDBM50007655
CC(C)(C)S(=O)(=O)C[C@H](CC(F)(F)F)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H28Cl2F3NO6S 610.478000 |
QDAZICLIUIVSJD-KKSHJYNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50007655
|
Local ready
Direct docking supported
|
|
E3L043475
BDB043475
|
BDBM50007656
CC(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H33Cl2NO6S 570.535000 |
RQNXTFPPWHDPDU-WMMXXEOUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007656; PubChem:CID89480425
|
Local ready
Direct docking supported
|
|
E3L043476
BDB043476
|
BDBM50007657
CC(C)(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H35Cl2NO6S 584.562000 |
FMXNELLNMOXQLN-WMMXXEOUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007657; PubChem:CID90342165
|
Local ready
Direct docking supported
|
|
E3L043477
BDB043477
|
BDBM50007658
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H33Cl2NO6S 570.535000 |
NCNVGCDVSSOKED-UCXAEWMPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50007658; PubChem:CID89480496
|
Local ready
Direct docking supported
|
|
E3L043478
BDB043478
|
Tanespimycin
C=CCNC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O
|
C31H43N3O8 585.698000 |
AYUNIORJHRXIBJ-TXHRRWQRSA-N | P29375 | Lysine-specific demethylase 5A |
BindingDB, PubChem
BindingDB:BDBM50008057; PubChem:CID6505803
|
Local ready
Direct docking supported
|
|
E3L043479
BDB043479
|
Geldanamycin
COC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O
|
C29H40N2O9 560.644000 |
QTQAWLPCGQOSGP-KSRBKZBZSA-N | P29375 | Lysine-specific demethylase 5A |
BindingDB, PubChem
BindingDB:BDBM50008059; PubChem:CID5288382
|
Local ready
Direct docking supported
|
|
E3L043480
BDB043480
|
BDBM50008120
O=C(Nc1nc([C@H](NC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)N2CCOCC2)C(=O)N[C@@H](CC2CCCCC2)C(O)C(F)(F)C(=O)NCCN2CCOCC2)cs1)OCc1ccccc1
|
C43H58F2N8O10S2 949.113000 |
ZDLVIZHUELHGBX-MOENERJOSA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50008120
|
Local ready
Direct docking supported
|